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  • Goserelin Acetate

    Description

    This page contains brief details about the drug goserelin acetate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Goserelin Acetate is a gonadotropin-releasing hormone agonist. Goserelin Acetate 3.6mg implant was approved in 1989 whereas Goserelin Acetate 10.8mg was approved in 1996.

    Mechanism of Action of Goserelin Acetate

    Goserelin Acetate is a synthetic analogue of gonadotropin releasing hormone that binds to the gonadotropin receptors of pituitary gland. It lowers the androgen and testosterone levels in men and oestrogen levels in women. It is prescribed in combination with androgen antagonist like flutamide to prevent the initial flare up of tumor.

    Uses of Goserelin Acetate

    Goserelin Acetate Injection is an anticancer medication indicated for the palliative treatment of Advanced prostate cancer and breast cancer. It is also indicated as an endometrial thinning agent in uterine bleeding and for the management of endometriosis.

    Goserelin Acetate Dosage available

    Goserelin Acetate is available as a prefilled syringe indicated as an implant in the doses 3.6mg, and 10.8mg.  It is administered through subcutaneous route.

  • Cilastatin+Imipenem

    Description

    This page contains brief details about the drug cilastatin,imipenem, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    The U.S. FDA approved cilastatin + imipenem in 1985. It is used in treating various complex infections in the abdominal region, lung-related infections like pneumonia, and those occurring around the time of childbirth. Additionally, it proves effective against complicated urinary tract infections as well as skin and soft tissue infections. Moreover, this medicine finds utility in managing patients with low white blood cell counts and suspected bacterial-induced fevers. Furthermore, it serves as a viable option for treating bloodstream infections potentially linked to the types of infections.

    Mechanism of Action of Cilastatin+Imipenem

    Cilastatin acts as a blocker of renal dehydropeptidase-I. Because Imipenem, the antibiotic, is broken down by this enzyme found in the kidney, cilastatin is given alongside imipenem to prevent its breakdown and keep it effective.

    Uses of Cilastatin+Imipenem

    Cilastatin + imipenem is used to induce muscle relaxation in tracheal tube insertion for artificial ventilation and in intensive care unit surgery (ICU).

    Cilastatin+Imipenem Dosage available

    This medicine is given only in a hospital setup by a healthcare provider. cilastatin + imipenem will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.

  • Dapagliflozin+Metformin

    Description

    This page contains brief details about the drug dapagliflozin,metformin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Dapagliflozin + Metformin is an anti-diabetic drug. Dapagliflozin belongs to the group of medications called sodium-glucose co-transporter. Metformin belongs to the class of medications called biguanides. FDA approved this medicine on October 30, 2014, for its medical use.

    Mechanism of Action of Dapagliflozin+Metformin

    Dapagliflozin reduces glucose reabsorption and lowers the renal threshold for glucose. It works by removing excess sugar from your body via your urine and lowering the sugar in your blood. Metformin primarily decreases hepatic glucose production and decreases intestinal absorption of glucose. It works mainly by inhibiting glucose production in the liver.

    Uses of Dapagliflozin+Metformin

    Dapagliflozin + Metformin is available as a tablet.  It treats type 2 diabetes mellitus in patients aged 18 years and older. This combination of medicines is taken by mouth (orally).

    Dapagliflozin+Metformin Dosage available

    It is an orally available prescription drug. Your doctor will decide the dose and duration of dapagliflozin + metformin based on the blood sugar and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time with food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

  • Liraglutide

    Description

    This page contains brief details about the drug liraglutide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Liraglutide is an anti-diabetic medication which was approved for its medical use on 25th January 2010.

    Mechanism of Action of Liraglutide

    Liraglutide is a glucagon-like peptide-1 agonist which is coupled to adenylate cyclase. GLP-1 stimulates the release of insulin and lowers glucose levels. It works by inhibiting glucagon secretion, delaying gastric emptying, and reducing the death of islet cells. It decreases hormones that raise blood sugar levels, slow digestion and reduce appetite.

    Uses of Liraglutide

    Liraglutide is a glucagon-like peptide-1 agonist which is coupled to adenylate cyclase. GLP-1 stimulates the release of insulin and lowers glucose levels. It works by inhibiting glucagon secretion, delaying gastric emptying, and reducing the death of islet cells. It decreases hormones that raise blood sugar levels, slow digestion and reduce appetite.

    Liraglutide Dosage available

    Liraglutide is available as a solution for injection in doses of 0.6 mg, 1.2 mg, or 1.8 mg. It is intended for subcutaneous administration into the abdomen or thigh. Only use if the solution is clear, colorless, and contains no particles. Do not double the dose to compensate for the one you missed. Even if the needle is replaced, avoid sharing Liraglutide with other patients.

  • Mesna

    Description

    This page contains brief details about the drug mesna, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Mesna is a cytoprotectant drug that belongs to the class of hemorrhagic cystitis inhibitors.  FDA-approved mesna initially on 1998 for the treatment of hemorrhagic cystitis.

    Mechanism of Action of Mesna

    Mesna reduces ifosfamide (cancer medication) induced hemorrhagic cystitis by binding to certain metabolites, inhibiting their toxic effects on the bladder.

    Uses of Mesna

    Mesna is an intravenously administered drug. This medicine is used to reduce the risk of hemorrhagic cystitis (a condition that causes bladder inflammation and can result in serious bleeding) in people who receive ifosfamide (a medication used for treating cancer). It protects against some of the harmful effects of certain chemotherapy medications.

    Mesna Dosage available

    Mesna is available as an intravenous injection. The drug should be administered only by healthcare professionals experienced with cancer chemotherapy. Your physician will determine the dose and frequency of administration based on the type of cancer and severity of the disease. Do not self-administer the injection.

  • Dulaglutide

    Description

    This page contains brief details about the drug dulaglutide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Dulaglutide contains active components as dulaglutide. It is a medication that is used to treat type 2 diabetes. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Dulaglutide works by mimicking the action of a hormone called glucagon-like peptide-1 (GLP-1) in the body. It is typically used in combination with other diabetes medications, such as metformin or sulfonylureas, when diet and exercise alone are not sufficient to control blood sugar levels. This medication improves glycemic control and helps prevent hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). Many people with type 2 diabetes struggle with weight management. This medication has been shown to promote weight loss or maintenance in some individuals. This can benefit overall health and contribute to better diabetes management. It received FDA approval on September 17, 2014, for treating type 2 diabetes.

    Mechanism of Action of Dulaglutide

    Dulaglutide, a GLP-1 receptor agonist, improves glycemic control in individuals with type 2 diabetes by stimulating insulin secretion, suppressing glucagon release (a hormone that prevents excessive glucose production by the liver.), and slowing gastric emptying. These actions work together to lower blood sugar levels, promote weight loss or weight maintenance, and reduce appetite. By addressing multiple aspects of diabetes management, this medication offers a comprehensive therapeutic effect for individuals with type 2 diabetes.

    Uses of Dulaglutide

    Dulaglutide is a medication approved for the management of type 2 diabetes.

    Dulaglutide Dosage available

    Dulaglutide is typically administered by a healthcare professional once in a week. It is usually given as an injection. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.

  • Efavirenz+Emtricitabine+Tenofovir Disoproxil Fumarate

    Description

    This page contains brief details about the drug efavirenz,emtricitabine,tenofovir disoproxil fumarate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate is a complete regimen consisting of antiviral medications, which was approved for its medical use on 12th July 2006.

    Mechanism of Action of Efavirenz+Emtricitabine+Tenofovir Disoproxil Fumarate

    Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate Tablet is a combination of non-nucleoside reverse transcriptase inhibitor, nucleoside reverse transcriptase inhibitor and nucleotide reverse transcriptase inhibitors. It works by increasing the number of CD4 T cells and stimulates the immune system to fight against infections. Thereby, it reduces the viral load of HIV in the blood and decreases the severity of HIV infection.

    Uses of Efavirenz+Emtricitabine+Tenofovir Disoproxil Fumarate

    Efavirenz, Emtricitabine and Tenofovir disoproxil Fumarate is indicated as a complete regimen to treat human immunodeficiency virus infection in adults and paediatric patients older than 12 years of age.

    Efavirenz+Emtricitabine+Tenofovir Disoproxil Fumarate Dosage available Efavirenz, Emtricitabine and Tenofovir disoproxil fumarate is available as film coated tablets consisting of 600mg of Efavirenz, 200mg of Emtricitabine and 300mg of Tenofovir disoproxil fumarate. The usual recommended dosage of this combination regimen is one tablet every day, preferably at bedtime.

  • Atezolizumab

    Description

    This page contains brief details about the drug atezolizumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Atezolizumab is an anticancer drug belonging to the group of medicines called Programmed death ligand – 1 inhibitor (PDL-1). It was officially approved for its medical use in the year 2016.

    Mechanism of Action of Atezolizumab

    Atezolizumab is a humanized monoclonal antibody that belongs to the category of programmed death ligand – 1. Programmed death ligand is a protein that facilitates the suppression of T-cells by binding with immune and tumor cells. This leads to a poor immune response against cancer cells. Atezolizumab Injection acts against the signals of programmed death ligand – 1 and improves immune response by exhibiting specific cytotoxic activity.

    Uses of Atezolizumab

    Atezolizumab is indicated for various types of cancer as a monotherapy and also along with other anticancer medications. It is usually prescribed to treat urothelial carcinoma, liver cancer (hepatocellular carcinoma), small cell and non-small cell lung cancer, triple-negative breast cancer, and melanoma.

    Atezolizumab Dosage available

    Atezolizumab Injection is intended for intravenous administration. Your physician will inject this medicine as an infusion for the first 60 minutes and if it is well tolerated, the subsequent infusions will be administered for 30 minutes.

    Atezolizumab Injection is available as a single-use vial in doses 840mg/14ml and 1200mg/20ml. The ideal dosing for urothelial carcinoma, non-small cell and small cell lung cancers, hepatocellular carcinoma, and melanoma is 840mg every two weeks, 1200mg every 3 weeks, or 1680mg every four weeks.