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Get Access To Tofacitinib Tablets 5 mg
Tofacitinib Tablets is the first oral JAK inhibitor approved for use in chronic ulcerative colitis.In May 2018, the FDA approved tofacitinib citrate “for the treatment of adult patients in the U.S. with moderately to severely active ulcerative colitis.”
Tofacitinib Tablets
- Brand Name – On Request
- API – Tofacitinib Citrate
- Packaging – 60 Tablets
- Strength – 5 mg
- Manufacturer Name – Pfizer Labs
What is tofacitinib used for?
Tofacitinib Tablets is a Janus kinase (JAK) inhibitor indicated for the treatment of:
Rheumatoid Arthritis: in adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate. It may be used as monotherapy or in combination with methotrexate or other non biologic disease-modifying antirheumatic drugs (DMARDs).
Psoriatic Arthritis: in adult patients with active psoriatic arthritis who have had an inadequate response or intolerance to methotrexate or other disease-modifying antirheumatic drugs (DMARDs).
Ulcerative Colitis: in adult patients with moderately to severely active ulcerative colitis (UC), who have had an inadequate response or who are intolerant to TNF blockers.
- Brand Name – Xeljanz
- API – Tofacitinib Citrate
- Packaging – 60 Tablets
- Strength – 5 mg
- Manufacturer Name – Pfizer Labs
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Get Access To Tofacitinib Tablets 5 mg
Shreyaansh Lifesciences, Jaipur. India
Shreyaansh Lifesciences is registered in Jaipur, India. Registration Number : 08AEEFS9350K1ZI under GST Act.
Branch Offices in India : Jaipur | New Delhi
SF-72-73 2ND FLOOR, Jaipur Electronic Market, Ridhi Sidhi Choraha, Jaipur, Rajasthan, 302018.
+91 99292 77766
Facts of Medicines
TOFACITINIB SIDE EFFECTS
Rheumatoid and Psoriatic Arthritis: Most common side effects of tofacitinib include upper respiratory tract infection, nasopharyngitis, diarrhea, and headache.
Ulcerative Colitis: Most common adverse reactions include nasopharyngitis, elevated cholesterol levels, headache, upper respiratory tract infection, increased blood creatine phosphokinase, rash, diarrhea, and herpes zoster.
TOFACITINIB DOSAGE
Tofacitinib should be taken orally at about the same time each day, either with or without food. Tofacitinib tablets should be swallowed whole with water. The tablets should not be opened, broken, or Chewed.
SUPPLIED/STORAGE AND HANDLING
Care should be exercised in the handling of AFANAT. AFANAT tablets should not be opened or crushed. Store permitted between 15-30°C (59-86°F). Keep this medication in the original container and keep the container tightly closed also away from the moisture and light.
- Use of this medication in combination with biological therapies for UC or with potent immunosuppressants such as azathioprine and cyclosporine is not recommended.
- Patients should be closely monitored for the development of signs and symptoms of infection during and after treatment with Xeljanz 5 mg.
- Caution is also recommended in patients with a history of chronic lung disease, or in those who develop interstitial lung disease, as they may be more prone to infections.
- Risk of infection could be greater with an increasing degree of the lymphopenia and consideration must be given to lymphocyte counts when assessing individual patient risk of infection. Interruption and monitoring criteria for the lymphopenia must be recommended.
- Consultation with a healthcare professional or physician with the expertise in the treatment of tuberculosis must be recommended in order to aid in the decision about whether starting anti-tuberculosis therapy is appropriate for an individual patient.
- Patients should be closely and precisely monitored for the development of symptoms of tuberculosis, including patients who found negative for the latent tuberculosis infection before initiating therapy.
- Non-melanoma skin cancers (NMSCs) have been reported in patients treated with XELJANZ 5MG. Skin examination should be recommended periodically for patients who are at increased risk for skin cancer.
- Avoid Xeljanz Rheumatoid Arthritis drug in patients that may be at increased risk of thrombosis.
- Tofacitinib 5 mg must be used with a lot of caution in patients who are at increased risk for gastrointestinal perforation.
- Patients presenting with the new onset abdominal signs should be observed promptly for early identification of the gastrointestinal perforation.
- Hypersensitivity has been observed in patients receiving XELJANZ 5MG TABLET. In case if a serious hypersensitivity reaction appears, promptly discontinue or interrupt this drug while evaluating the potential causes of reactions.
- Patients with psoriatic arthritis treatment should be monitored for lymphocyte counts at baseline and every 3 months thereafter. Recommended modifications should be based on the lymphocyte counts.
- Routine monitoring of liver tests should be recommended and prompt investigation of the causes of the liver enzyme elevations is also recommended in order to identify the potential cases of drug-induced liver injury.
FAQs – Medicine Questions
What is the active ingredients of Xeljanz?
Tofacitinib citrate is the active ingredient.
What are the inactive ingredients in the medicine Tofacitinib?
The inactive ingredients are croscarmellose sodium, HPMC 2910/Hypromellose 6cP, lactose monohydrate, macrogol/PEG3350, magnesium stearate, microcrystalline cellulose, titanium dioxide, and triacetin.
Is xeljanz associated with an increased incidence of neutropenia?
Yes, treatment with XELJANZ is associated with an increased incidence of neutropenia.
Where can I buy Tofacitinib Tablets?
You can buy Tofacitinib Tablets from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.
The buyer should check the existing law in their home country before importing the product.
What is the procedure to buy Tofacitinib Tablets?
Patients can simply fill the order form or can send mail at info@treatmentoptions4u.com. Patients can also send WhatsApp messages to +91 98738 10020. We will reply ASAP with the details of the Tofacitinib Tablets price as well as procurement procedure.
Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.
Is Xeljanz safe for Pregnant women?
The medication should be avoided to use in pregnant women.
NEWS / UPDATES
- Pfizer, Electronic medicines compendium (emc), [ Revised on march 2017] [ Accessed on 7th April 2021], https://www.medicines.org.uk/emc/product/2500/smpc
- Pfizer, US Food and Drug Administration, [ Revised on May 2018] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/203214s018lbl.pdf
- Dhillon S; Tofacitinib: A Review in Rheumatoid Arthritis. Drugs; Drugs 2017; Accessed 07/04/2021 https://pubmed.ncbi.nlm.nih.gov/29139090/
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