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mepolizumab for injection
Mepolizumab is an interleukin-5 (IL-5) antagonist monoclonal antibody (IgG1 kappa) indicated for Add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype. The treatment of adult patients with eosinophilic granulomatosis with polyangiitis (EGPA).

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Mepolizumab for injection

  • API – mepolizumab injection, for subcutaneous use
  • Packaging – Injection: 100 mg/mL, single-dose, prefilled autoinjector or single-dose
  • Strength – For injection: 100 mg of lyophilized powder in a single-dose vial . 
    Manufacturer Name – GlaxoSmithKline

What is Mepolizumab used for?

Mepolizumab is a humanized monoclonal antibody used for the treatment of severe eosinophilic asthma, eosinophilic granulomatosis, and hypereosinophilic syndrome (HES). It recognizes and blocks interleukin-5 (IL-5), a signalling protein of the immune system.

Mepolizumab is approved by the U.S. Food and Drug Administration (FDA) for the maintenance treatment of severe asthma in patients aged six years or older and with an eosinophilic phenotype in combination with other medicines used to treat asthma. In the European Union it is approved as an add-on treatment for severe refractory eosinophilic asthma in adults.

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