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Piperacillin/tazobactam was approved for medical use in the United States in 1993. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic medication.
Piperacillin-tazobactam is recommended by the National Institute for Health and Care Excellence as first-line therapy for the treatment of bloodstream infections in neutropenic cancer patients.
Piperacillin and Tazobactam Injection
Generic Name – Piperacillin and Tazobactam
Packaging – Powder for Solution for Infusion
Strength – 4g/0.5gGeneric
Brand Available – pipramed
What is Piperacillin and Tazobactam Injection used for?
Piperacillin and tazobactam injection is used to treat pneumonia and skin, gynecological, and abdominal (stomach area) infections caused by bacteria. Piperacillin is in a class of medications called penicillin antibiotics. It works by killing bacteria that cause infection.
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Get Access To Piperacillin and Tazobactam Injection 4.5 gm
Facts of Medicines
How Supplied / Storage & Handling
The piperacillin tazobactam injection vials should be stored at controlled room temperature (20°C to 25°C [68°F to 77°F]) prior to reconstitution.
Piperacillin/Tazobactam should be administered by intravenous infusion over 30 minutes. The usual daily dose of piperacillin tazobactam for adults is 3.375 g every 6-hours totaling 13.5 g (12.0 g piperacillin/1.5 g tazobactam).
Nosocomial Pneumonia: The initial presumptive therapy of patients with nosocomial pneumonia should start with dosage piperacillin tazobactam 4.5 g every six hours plus an aminoglycoside, totaling 18.0 g (16.0 g piperacillin/2.0 g tazobactam).
For children with peritonitis and/or appendicitis the recommended piperacillin and tazobactam injection ip dosage is 100 mg piperacillin/12.5 mg tazobactam per kg of body weight, every 8-hours in pediatric patients aged 9 months and older. For pediatric patients aged 2 to 9 months, the standard dosage is 80 mg piperacillin/10 mg tazobactam per kg of body weight, every 8-hours.
Side Effects of Piperacillin/tazobactam
The most commonly reported Piperacillin Tazobactam side effects include: diarrhea, constipation, headache, nausea and insomnia.
Warning and Precautions
The use of piperacillin tazobactam 4.5 g is restricted in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or β-lactamase inhibitors.
Prior to initiating therapy with piperacillin and tazobactam injection ip 4.5 gm, careful inquiry should be made concerning any kind of previous hypersensitivity reactions.
Dosage in patients with renal impairment (≤40 mL/min of CRCL) and dialysis patients should be decreased, on behalf of the degree of actual renal function impairment.
In case patients develop a skin rash they should be evaluated closely and piperacillin tazobactam discontinued if lesions progress.
Periodic assessment of hematopoietic function needs to be performed, especially with prolonged therapy, ie, ≥ 21 days.
As with other existing penicillins, patients may have neuromuscular excitability or convulsions if greater than prescribed doses of piperacillin tazobactam injection are given intravenously (mainly in the presence of renal failure).
The combined administration of vancomycin and piperacillin/tazobactam may be associated with an increased incidence of acute kidney injury.
FAQs – Medicine Questions
What is Piperacillin Tazobactam?
Piperacillin Tazobactam is a combination drug containing the antibiotic piperacillin and the β-lactamase inhibitor tazobactam. It has activity against several Gram +Ve and Gram -Ve bacteria including Pseudomonas aeruginosa. It aimed to treat pelvic inflammatory disease, cellulitis, intra-abdominal infection, pneumonia, and sepsis.
What are dosage strengths of piperacillin tazobactam?
The piperacillin tazobactam iv medicinal product is supplied as 4 g/0.5 g Powder for Solution for Infusion.
How is Piperacillin Tazobactam administered?
The Piperacillin Tazobactam comes as an injection for intravenous infusion.
Where can I buy piperacillin tazobactam injection?
You can buy piperacillin and tazobactam injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.
The buyer should check the existing law in their home country before importing the product.
What is the procedure to buy piperacillin tazobactam?
Patients can simply fill the order form or can send mail at firstname.lastname@example.org. Patients can also send WhatsApp messages to +91 98738 10020. We will reply ASAP with the details of the piperacillin tazobactam price as well as procurement procedure.
Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.
What type of drug is Piperacillin Tazobactam?
Piperacillin Tazobactam specifically is a type of antibacterial and β-lactamase inhibitor drug.
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