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Defibrotide Sodium Injection 200 mg
Defibrotide Sodium Injection is used to treat adults and children with hepatic veno-occlusive disease (VOD; blocked blood vessels inside the liver, also known as sinusoidal obstruction syndrome), who have kidney or lung problems after receiving a hematopoietic stem-cell transplant (HSCT; procedure in which certain blood cells

Defibrotide Sodium Injection was approved for medical use in the United States in 2016. It is on the World Health Organization’s List of Essential Medicines.

Defibrotide Sodium Injection Available Price In India UK Saudi Arabia

Defibrotide Sodium Injection

  • Generic Brand Available – Defitelio
  • API – Defibrotide Sodium
  • Packaging – Glass Bottle
  • Strength – 200 mg/2.5ml, 80mg/ml

What is Defibrotide Sodium Injection used for?

Defibrotide Sodium Injection (DEFITELIO) is indicated for the treatment of adult and pediatric patients with hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), with renal or pulmonary dysfunction following hematopoietic stem-cell transplantation (HSCT)

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    Get Access To Defibrotide Sodium Injection 200 mg

    Shreyaansh Lifesciences, Jaipur. India

    Shreyaansh Lifesciences is registered in Jaipur, India. Registration Number : 08AEEFS9350K1ZI under GST Act. 
    Branch Offices in India : Jaipur | New Delhi

    SF-72-73 2ND FLOOR, Jaipur Electronic Market, Ridhi Sidhi Choraha, Jaipur, Rajasthan, 302018.

    +91 99292 77766

    Facts of Medicines

    Defibrotide Sodium Injection 200 mg

    INDICATIONS AND USAGE
    DEFITELIO is indicated for the treatment of adult and pediatric patients with hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), with renal or pulmonary dysfunction following hematopoietic stem-cell transplantation (HSCT).

    DOSAGE AND ADMINISTRATION
    • Administer DEFITELIO 6.25 mg/kg every 6 hours given as a 2-hour intravenous infusion. 
    • Treat for a minimum of 21 days. If after 21 days signs and symptoms of VOD have not resolved, continue treatment until resolution.
    Injection: 200 mg/2.5 mL (80 mg/mL) in a single-patient-use vial.

    ADVERSE REACTIONS
    The most common adverse reactions (incidence ≥10% and independent of causality) with DEFITELIO treatment were hypotension, diarrhea, vomiting, nausea and epistaxis

    WARNINGS AND PRECAUTIONS

    • DEFITELIO increased the activity of fibrinolytic enzymes in vitro, and it may increase the risk of bleeding in patients with VOD after hematopoietic stem-cell transplantation (HSCT). Do not initiate DEFITELIO in patients with active bleeding. Monitor patients for signs of bleeding. If patients on DEFITELIO develop bleeding, discontinue DEFITELIO, treat the underlying cause, and provide supportive care until the bleeding has stopped.
    • Hypersensitivity reactions have occurred in less than 2% of patients treated with DEFITELIO. These reactions include rash, urticaria and angioedema. One case of an anaphylactic reaction was reported in a patient who had previously received DEFITELIO. Monitor patients for hypersensitivity reactions, especially if there is a history of previous exposure. If a severe hypersensitivity reaction occurs, discontinue DEFITELIO, treat according to the standard of care, and monitor until symptoms resolve
    • No carcinogenicity studies have been conducted with intravenous administration of defibrotide sodium.

    •  Defibrotide sodium was not mutagenic in vitro in a bacterial reverse mutation assay (Ames assay). Defibrotide sodium was not clastogenic in an in vitro chromosomal aberrations assay in Chinese hamster ovary cells or an in vivo micronucleus assay conducted in bone marrow from rats administered defibrotide sodium by intravenous infusion.

      FAQs – Medicine Questions

      Defibrotide Sodium Injection 200 mg
      What is defibrotide Defibrotide Sodium Injection?
      Defibrotide injection is used to treat adults and children with hepatic veno-occlusive disease (VOD; blocked blood vessels inside the liver, also known as sinusoidal obstruction syndrome), who have kidney or lung problems after receiving a hematopoietic stem-cell transplant (HSCT; procedure in which certain blood cells
      What is defibrotide sodium?
      Defibrotide sodium is an oligonucleotide mixture with profibrinolytic properties. The chemical name of defibrotide sodium is polydeoxyribonucleotide, sodium salt.
      How do you administer a defibrotide?
      The recommended dosage of DEFITELIO for adult and pediatric patients is 6.25 mg/kg every 6 hours given as a 2- hour intravenous infusion. The dose should be based on patient’s baseline body weight, defined as the patient’s weight prior to the preparative regimen for HSCT. Administer DEFITELIO for a minimum of 21 days.
      Where can I buy Abacavir Defibrotide Sodium Injection?

      You can buy Defibrotide Sodium Injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

      The buyer should check the existing law in their home country before importing the product.

      What is the procedure to buy Defibrotide Sodium Injection?

      Patients can simply fill the order form or can send mail at info@treatmentoptions4u.com. Patients can also send WhatsApp messages to +91 99292 77766 / 98738 10020   We will reply ASAP with the details of the Defibrotide Sodium Injection price as well as procurement procedure.

      Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

      How long does defibrotide take to work?
      Defibrotide: administration, duration of use, actual given dose. The median delay to start DF was 1 day after the diagnosis of VOD (range 0–12 days). The median duration of treatment with DF was 17 days (range 1–83 days).

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