Category: Brain Malignancies

Description

This page contains brief details about the drug busulfan, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Busulfan is an anti-cancer medication that was approved to be used on 2 April 1999.

Mechanism of Action of Busulfan

Busulfan is an alkylating chemotherapeutic agent that works by interfering with the DNA replication process, which is necessary for the cells to divide. It stops tumor growth by inhibiting cell division.

Uses of Busulfan

Busulfan is used to treat

Hematopoietic progenitor cell transplantation

Chronic myelogenous leukemia

Polycythaemia vera (a type of cancer that causes an increase in red blood cells)

Thrombocythemia (increased number of platelets in the blood)

Myelofibrosis (type of blood cancer where scar tissues are formed in bone marrow)

Hemoglobinopathies (a genetic disorder that produces abnormal hemoglobin)

Brain Malignancies

Busulfan Dosage available

Busulfan is available as a tablet that is to be swallowed whole with water. The available dose is 2mg.

Busulfan is an injection that is to be given only under the supervision of a qualified healthcare professional. The available dose is 6omg.