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Category: Hodgkin Lymphoma
Etoposide
Description
This page contains brief details about the drug etoposide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
ETOPOSIDEThe U.S. FDA approved Etoposide as an anticancer medication to treat a certain type of cancer on 11th April 1983.
Mechanism of Action of Etoposide
Etoposide works by inhibiting the activity of topoisomerase II (essential for cell replication) and DNA synthesis, which will prevent cancer cells from growing and multiplying, ultimately leading to cell death.
Uses of Etoposide
Etoposide treats testicular, small-cell lung, acute myeloid leukemiaacute myeloid leukemia (blood cancer), Hodgkin’s and non-Hodgkin’s lymphoma, and ovarian cancer. This medicine can prevent the proliferation of cancer cells and prevents cell division which ultimately leads to cell death.
Etoposide Dosage available
It is an intravenous infusion drug that is injected through the veins. Your physician will choose the dosage and administration frequency based on your medical condition because it differs for each person.
Pegaspargase
Description
This page contains brief details about the drug pegaspargase, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Pegaspargase is a chemotherapy drug containing the active constituent pegaspargase. It is used to treat a type of blood cancer called Acute Lymphoblastic Leukemia (ALL).This is a white blood cell cancer in which the immature white cells start growing out of control, thus preventing the production of functional blood cells. Combined with other chemotherapy drugs, this medication can help increase the chances of remission and long-term survival for people with ALL.
Pegaspargase received its initial FDA approval in 1994 for treating leukemia. Since then, it has also been approved for use in various other countries. This medication is a prescription medication and should only be used under the supervision of a healthcare provider. It is particularly effective in treating children with ALL, who have a higher rate of remission and overall survival when included in their treatment plan.
Mechanism of Action of Pegaspargase
Pegaspargase is an enzyme that breaks down the amino acid asparagine in the body. Cancer cells require asparagine to grow and divide and cannot produce their asparagine. By breaking down asparagine in the body, this medication can effectively “starve” cancer cells of this essential nutrient, slowing their growth and promoting cancer cell death. However, normal cells in the body can produce their asparagine and are not as affected by the enzyme as cancer cells. Therefore, this medicine selectively targets cancer cells while sparing healthy cells in the body to some extent.
Uses of Pegaspargase
Pegaspargase is an antineoplastic agent used to treat certain types of cancer, particularly acute lymphoblastic leukemia (ALL) and Non- Hodgkin’s lymphoma.
Pegaspargase Dosage available
Pegaspargase is an enzyme that breaks down the amino acid asparagine in the body. Cancer cells require asparagine to grow and divide and cannot produce their asparagine. By breaking down asparagine in the body, this medication can effectively “starve” cancer cells of this essential nutrient, slowing their growth and promoting cancer cell death. However, normal cells in the body can produce their asparagine and are not as affected by the enzyme as cancer cells. Therefore, this medicine selectively targets cancer cells while sparing healthy cells in the body to some extent.
Brentuximab Vedotin
Description
This page contains brief details about the drug brentuximab vedotin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The Brentuximab vedotin is medically approved for the treatment of Hodgkin lymphoma, cutaneous T-cell lymphoma and systemic Anaplastic Large Cell Lymphoma.
Mechanism of Action of Brentuximab Vedotin
Brentuximab vedotin consists of an antibody targeting CD30, a protein found on the surface of cancer cells, and a chemotherapy drug attached to the antibody. The antibody delivers the chemotherapy directly to the cancer cells, minimizing damage to healthy cells.
Uses of Brentuximab Vedotin
Brentuximab vedotin is used to treat various cancers, including classical Hodgkin lymphoma (both newly diagnosed and relapsed), systemic anaplastic large cell lymphoma, primary cutaneous anaplastic large cell lymphoma, cutaneous T-cell lymphoma, and CD30-expressing mycosis fungoides, all in combination with other therapies.
Brentuximab Vedotin Dosage available
Brentuximab vedotin can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.