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Category: Endometriosis
Goserelin Acetate
Description
This page contains brief details about the drug goserelin acetate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Goserelin Acetate is a gonadotropin-releasing hormone agonist. Goserelin Acetate 3.6mg implant was approved in 1989 whereas Goserelin Acetate 10.8mg was approved in 1996.
Mechanism of Action of Goserelin Acetate
Goserelin Acetate is a synthetic analogue of gonadotropin releasing hormone that binds to the gonadotropin receptors of pituitary gland. It lowers the androgen and testosterone levels in men and oestrogen levels in women. It is prescribed in combination with androgen antagonist like flutamide to prevent the initial flare up of tumor.
Uses of Goserelin Acetate
Goserelin Acetate Injection is an anticancer medication indicated for the palliative treatment of Advanced prostate cancer and breast cancer. It is also indicated as an endometrial thinning agent in uterine bleeding and for the management of endometriosis.
Goserelin Acetate Dosage available
Goserelin Acetate is available as a prefilled syringe indicated as an implant in the doses 3.6mg, and 10.8mg. It is administered through subcutaneous route.
Triptorelin
Description
This page contains brief details about the drug triptorelin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Triptorelin was approved for its medical use on 15th June 2000 by the US Food and Drug Administration. It is a medication that belongs to a class of drugs known as gonadotropin-releasing hormone (GnRH) analogs. It is primarily used in the field of reproductive medicine for the treatment of various conditions related to hormonal imbalance.
Mechanism of Action of Triptorelin
Triptorelin exerts its therapeutic effect by suppressing the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) through its action on the pituitary gland. This suppression leads to a decrease in the production of sex hormones, such as testosterone and estrogen. By reducing the levels of these hormones, this medication is beneficial in treating hormone-dependent conditions such as prostate cancer, breast cancer, and endometriosis.
Uses of Triptorelin
Triptorelin is used for the treatment of Prostate cancer in men, Early onset puberty in children 2 years of age and older (precocious puberty) and used to treat Endometriosis in females – a condition in which the tissue that normally lines the uterus—grows outside of it.
Triptorelin Dosage available
Triptorelin is available as a vial for injection in the doses 3.75mg, 11.25mg and 22.5mg. It is administered as an intramuscular injection into either of the buttocks. Triptorelin is typically administered via injection, either subcutaneously (under the skin) or intramuscularly (into the muscle). The specific dosing and frequency of administration will depend on the individual’s condition being treated and their response to the medication. It is important to follow the healthcare professional’s instructions regarding the administration technique and schedule.