Category: Fungal Infections

Description

This page contains brief details about the drug micafungin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Micafungin was initially approved by the United States Food and Drug Administration (FDA) on January 17, 2005.

Mechanism of Action of Micafungin

Micafungin works by inhibiting the synthesis of a crucial component in the fungal cell wall called beta-glucan. This disruption weakens the structural integrity of the cell wall, leading to increased permeability and ultimately causing the death of the fungal cell.

Uses of Micafungin

Micafungin is used to treat a range of serious fungal infections caused by specific types of fungi. It is indicated for the treatment of invasive candidiasis, including candidemia, intra-abdominal candidiasis, and infections of the esophagus caused by Candida species. Additionally, it is used for the treatment of invasive aspergillosis and to initiate empirical antifungal therapy in certain circumstances. It is also used in managing fever in patients with low white blood cell counts (neutropenic fever) often associated with chemotherapy.

Micafungin Dosage available

Micafungin works by inhibiting the synthesis of a crucial component in the fungal cell wall called beta-glucan. This disruption weakens the structural integrity of the cell wall, leading to increased permeability and ultimately causing the death of the fungal cell.

Description

This page contains brief details about the drug flucytosine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Flucytosine is an anti-fungal drug developed by the U.S. Food And Drug Administration and initially approved for treating fungal infections.

Mechanism of Action of Flucytosine

Flucytosine works by interfering with the synthesis of fungal DNA and RNA. This disrupts the growth and replication of fungal cells, helping to control and eliminate the infection.

Uses of Flucytosine

Flucytosine is used to treat serious fungal infections caused by specific types of fungi. It is considered an important component in managing infections caused by fungi like Cryptococcus and Candida species, which can be particularly problematic in individuals with weakened immune systems. It’s often combined with other antifungal drugs to enhance treatment effectiveness.

Flucytosine Dosage available

Take the Flucytosine as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Description

This page contains brief details about the drug caspofungin acetate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The U.S. FDA approved Caspofungin Acetate for fungal infections on December 30, 2004. This belongs to the medication class known as an antifungal.

Mechanism of Action of Caspofungin Acetate

Caspofungin Acetate works by weakening fungal cells and inhibiting their growth, preventing the spread of infection. This allows the body’s natural defenses to effectively eliminate the infection.

Uses of Caspofungin Acetate

Caspofungin Acetate is used in the treatment of candidemia, esophageal candidiasis, other Candida infections, and aspergillosis, which is a fungal infection in the lungs.

Caspofungin Acetate Dosage available

Caspofungin Acetate will be administered to you by a healthcare professional in a hospital setting. It is usually administered in a vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Description

This page contains brief details about the drug anidulafungin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Anidulafungin is an antifungal medication developed by the U.S. Food And Drug Administration and initially approved on 21 Feb 2006 for treating serious fungal infections.

Mechanism of Action of Anidulafungin

Anidulafungin works by inhibiting the beta-glucan synthesis in the cell walls of susceptible fungi. This disruption weakens the fungal cell wall, leading to the death of the fungus.

Uses of Anidulafungin

Anidulafungin helps to treat certain invasive fungal infections. It is effective against various types of invasive candidiasis, such as candidemia (Candida bloodstream infection) and esophageal candidiasis (fungal infection affecting the esophagus). Invasive candidiasis occurs when candida yeasts enter the bloodstream or other internal organs and cause systemic infections.

Anidulafungin Dosage available

Anidulafungin is administered directly into the vein intravenously (IV). It is available as a powder for reconstitution, and a physician will prepare and administer the medication through a vein. The IV infusion is usually given over a period of one to two hours.

Description

This page contains brief details about the drug amphotericin b, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Amphotericin B is an antifungal antibiotic. FDA approved this medicine on 11th August 1997 for its medical use.

Mechanism of Action of Amphotericin B

Amphotericin B binds primarily to ergosterol in sensitive fungi cell membranes, causing membrane permeability changes that result in leakage of intracellular contents and cell death.

Uses of Amphotericin B

It is used to treat fungal infections of one or more deep body organs. It is also used to treat suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells). It is also indicated to treat visceral leishmaniasis, a disease caused by a parasite in certain people.

Amphotericin B Dosage available

A doctor or nurse in a hospital or clinic setting will give it to you. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.