Category: Hodgkin’s Disease.

Description

This page contains brief details about the drug dacarbazine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Dacarbazine is an anticancer drug that belongs to the category of medicines known as alkylating agents. It was approved in May 1975 to treat Metastatic malignant melanoma.

Mechanism of Action of Dacarbazine

It is a type of alkylating agent, which works majorly through the process of alkylation. It enters the cancer cells after getting activated by the liver and inhibits DNA synthesis. This process disrupts the normal cell cycle and DNA function, leading to arrest in cancer cell growth and multiplication.

Uses of Dacarbazine

Dacarbazine has been developed as a first-line agent to treat advanced and metastatic malignant melanoma. This drug is also prescribed to treat Hodgkin’s disease.

Dacarbazine Dosage available

Dacarbazine will be administered to you by a healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The specific dose and schedule of administration depend on the type and stage of the cancer being treated. This injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy). During the infusion, you will be monitored for any side effects or reactions to the medication. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.