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Category: Nausea and Vomiting
Palonosetron
Description
This page contains brief details about the drug palonosetron, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Palonosetron is an antiemetic drug that belongs to the category of medicines known as alkylating agents. It was approved by the FDA in July 2003 to treat Chemotherapy induced nausea and vomiting.
Mechanism of Action of Palonosetron
Palonosetron is an Isoquinoline derivative that interacts with 5-HT3 receptor antagonists. It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting.
Uses of Palonosetron
Palonosetron is an anti-emetic agent used to treat Postoperative nausea & vomiting. It is also used in the treatment of Chemotherapy induced nausea & vomiting.
Palonosetron Dosage available
Palonosetron is a prescription drug available only in tablet and injection form. The medicine will be administered to you by a qualified healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Palonosetron Hydrochloride Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. If you are taking palonosetron as an oral tablet, it should be swallowed whole with a glass of water, with or without food, as directed by your healthcare provider. Do not crush, chew, or break the tablet before swallowing it.
Daunorubicin
Description
This page contains brief details about the drug daunorubicin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Daunorubicin is an anti-cancer drug containing the active constituent daunorubicin. This chemotherapy medication belongs to the anthracycline class of drugs. It is used in the treatment of leukemia. In leukemia, the white blood cells produced in the bone marrow multiply uncontrolled and abnormally. Leukemia is associated with severe infection, extreme tiredness, and joint pain. It is necessary to inform your doctor if you have an infection, cardiac diseases, mouth ulcers, chickenpox or shingles (viral infection), fever, radiation treatment to the chest, kidney stones, and liver disorders.
Daunorubicin was first approved by the FDA in 1979 for the treatment of acute myeloid leukemia (AML). Since then, Daunorubicin has been approved for additional indications and formulations, including for the treatment of solid tumors and lymphomas. Like many chemotherapy drugs, it can cause side effects such as nausea, vomiting, hair loss, fatigue, and an increased risk of infection due to its effect on the immune system.
Mechanism of Action of Daunorubicin
The therapeutic effect of daunorubicin is to inhibit the growth and replication of cancer cells. As a chemotherapy medication, daunorubicin works by binding to DNA and interfering with its replication and transcription, ultimately leading to cell death. Doing so can help shrink tumors, prevent cancer from spreading to other parts of the body, and potentially cure cancer in some cases.
Uses of Daunorubicin
Daunorubicin is primarily used to treat acute myeloid leukemia (AML), a type of cancer that affects the blood and bone marrow. It can also be used to treat other types of cancer, including acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), lymphoma, and solid tumors such as breast and ovarian cancer.
Daunorubicin Dosage available
Daunorubicin is typically administered as an intravenous (IV) infusion or injection in a hospital or clinical setting by a healthcare provider. The exact dosing and frequency of administration will depend on the specific condition being treated and other individual factors, such as the patient’s age, weight, and overall health. If a dose is missed, it’s important to contact your healthcare provider as soon as possible to determine the appropriate course of action. Suppose the missed dose is discovered within a few hours of the scheduled time. In that case, your healthcare provider may recommend administering the missed dose as soon as possible while maintaining the usual interval between doses. However, if more than a few hours have passed since the missed dose, your healthcare provider may recommend skipping the missed dose and resuming the regular dosing schedule at the next scheduled time. It’s important not to double up on doses to make up for a missed one.
Netupitant+Palonosetron
Description
This page contains brief details about the drug netupitant,palonosetron, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Netupitant, Palonosetron is an antiemetic drug that belongs to the category of medicines known as alkylating agents. It was approved by the FDA in July 2003 to treat Chemotherapy-induced nausea and vomiting.
Mechanism of Action of Netupitant+Palonosetron
It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. The chemotherapeutic trigger zone( CTZ) contains the receptor serotonin, when this CTZ is stimulated, vomiting occurs. Palonosetron prevents the signals from serotonin and helps to reduce the symptoms of nausea and vomiting.
Uses of Netupitant+Palonosetron
Netupitant, Palonosetron is an anti-emetic agent used to treat Postoperative nausea & vomiting. It is also used to treat Chemotherapy induced nausea & vomiting.
Netupitant+Palonosetron Dosage available
Netupitant,Palonosetron is a prescription drug available in tablet and injection form. The medicine will be administered to you by a healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Palonosetron Hydrochloride Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. If you are taking palonosetron as an oral tablet, it should be swallowed whole with a glass of water, with or without food, as directed by your healthcare provider.
Granisetron Hydrochloride
Oncology
Ondansetron Hydrochloride
Oncology
Granisetron
Description
This page contains brief details about the drug granisetron, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Granisetron is an antiemetic drug that belongs to the class 5-HT 3 receptor antagonists and is effective against nausea and vomiting. It was approved by the FDA on 25 July 1
Mechanism of Action of Granisetron
Granisetron is a potent, selective antagonist of 5-HT3 receptors. The antiemetic (effective against vomiting and nausea) activity of the drug is brought about through the inhibition of 5-HT3 receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HT3 receptors, in turn, blocks the substance serotonin, a natural substance in the body that causes nausea and vomiting.
Uses of Granisetron
Granisetron is indicated to prevent nausea and vomiting associated with initial and repeated courses of emetogenic (a substance that causes vomiting) chemotherapy and radiation therapy. It is also used to treat and prevent nausea and vomiting in adults that may occur after surgery.
Granisetron Dosage available
Granisetron is a prescription generic drug available as an injectable solution, extended-release subcutaneous injection, transdermal patch, tablet, and oral solution. The oral dose is given 1 hour before chemotherapy, followed by 12 hours after chemotherapy to prevent chemotherapy-induced nausea and vomiting. The recommended injection dose is 10 mcg/kg intravenously 30 minutes before chemotherapy. Your doctor will decide the dose, frequency, and dosage based on the severity of the condition. To prevent radiation-induced nausea and vomiting, the recommended dose is given orally 1 hour before radiation therapy. To prevent postoperative nausea and vomiting, the recommended dose is given intravenously before induction of anesthesia. To treat postoperative nausea and vomiting, the recommended dose is given intravenously.
Ondansetron
4MG; 8MG Tablets