WHAT IS AFILBERCEPT, AND WHAT IT IS USED FOR?

Aflibercept, is a medication used to treat wet macular degeneration and metastatic colorectal cancer. It was developed by Regeneron Pharmaceuticals and is approved in the United States and the European Union.
It is used for the treatment of wet macular degeneration and is administered as an intravitreal injection, that is, into the eye. For cancer treatment, is given intravenously in combination with the other cancer drugs 5-fluorouracil and irinotecan and the adjuvant folinic acid.

On 27 August 2014, Aflibercept was also indicated for the treatment of people with visual impairment due to diabetic macular oedema, according to the updated summary of product characteristics. In May 2019 FDA expanded the indication for aflibercept to include all stages of diabetic retinopathy.

Note: (For Prescribing Information Approved Drugs, see)

• The Food and Drug Administration (FDA), USA.
• The European Medicines Agency (EMA).