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Ibrutinib Tablet 140 mg
This medication is used to treat certain cancers (such as mantle cell or marginal zone lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma, Waldenstrom's macroglobulinemia). Ibrutinib belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells.

It was approved by the US Food and Drug Administration (FDA) on November 13, 2013, for the treatment of mantle cell lymphoma. On February 12, 2014, the FDA expanded the approved use of ibrutinib to chronic lymphocytic leukemia (CLL). It was approved for Waldenström’s macroglobulinemia in 2015.

Ibrutini-capsules price, Available in Delhi, India, U.K.

Ibrutinib Tablet

  • Generic Brand Name – Ibrunat
  • Innovator Brand Name – Imbruvica
  • API – Ibrutinib
  • Packaging – 30 Capsules
  • Strength – 140 mg
  • Manufacturer Name – Natco Pharma

What is ibrutinib used for?

Ibrutinib is a kinase inhibitor used for the treatment of adult patients with:

  • Mantle cell lymphoma (MCL)
  • Chronic lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL). 
  • Chronic lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL) with 17p deletion. 
  • Waldenström’s macroglobulinemia (WM). 
  • Marginal zone lymphoma (MZL). 
  • Chronic graft versus host disease (cGVHD). 
Disclaimer

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Shreyaansh Lifesciences, Jaipur. India

Shreyaansh Lifesciences is registered in Jaipur, India. Registration Number : 08AEEFS9350K1ZI under GST Act. 
Branch Offices in India : Jaipur | New Delhi

SF-72-73 2ND FLOOR, Jaipur Electronic Market, Ridhi Sidhi Choraha, Jaipur, Rajasthan, 302018.

+91 99292 77766

Facts of Medicines

Ibrutinib Tablet 140 mg

HOW SUPPLIED/STORAGE AND HANDLING:

Care should be exercised in the handling of the IBRUNAT. IBRUNAT tablets should not be opened or broken. Tablets should be stored in the original packaging at room temperature 20°C-25°C (68°F-77°F). Excursions permitted between temperature 15°C-30°C (59°F-86°F).

IBRUTINIB SIDE EFFECTS

  • The most common adverse reactions in patients with B-cell malignancies (MCL, CLL/SLL, WM and MZL) include neutropenia, hemorrhage, musculoskeletal pain, thrombocytopenia, rash, diarrhea, anemia, nausea, bruising, fatigue, and pyrexia.
  • The most common adverse reactions in patients with cGVHD include fatigue, muscle spasms, thrombocytopenia, bruising, diarrhea, anemia, stomatitis, hemorrhage, pneumonia, and nausea.

DOSAGE

The recommended ibrutinib dose for patients with MCL and MZL is 560 mg, and for patients with CLL/SLL, WM, and cGVHD is 420 mg, which should be administered orally once daily. Dose should be administered orally with a glass of water. Do not open, break, or chew the capsules.

    WARNINGS AND PRECAUTIONS

    • Patients with the therapy of ibrutinib 140 mg should be monitored and evaluated for fever and infections and treated appropriately.
    • Patients taking treatment with imbruvica generic should be monitored for the complete blood counts monthly.
    • Patients should be monitored for new onset hypertension or hypertension that is not adequately controlled after initiating therapy with ibrutinib tablets.
    • Patients during ibrutinib treatment should be monitored clinically for the cardiac arrhythmias.
    • Administration of ibrutinib 140 mg to pregnant and breastfeeding women should be avoided.

      FAQs – Medicine Questions

      Ibrutinib Tablet 140 mg
      From which class of drug Ibrutinib belongs?

      Ibrutinib specifically belongs to the class of drugs named kinase inhibitors.

      How much water should I consume with Ibrunat?

      While taking Ibrunat 140 mg, consume at least 2-3 quarts of fluid in a day, unless you are instructed otherwise.

      How should Ibrutinib be administered?

      The recommended dose of ibrutinib tablet or capsules should be administered orally once daily at around the same time each day. Pills should be swallowed whole with water.

      Where can I buy Ibrutinib Tablet?

      You can buy Ibrutinib Tablet from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

      The buyer should check the existing law in their home country before importing the product.

      What is the procedure to buy Ibrutinib Tablet?

      Patients can simply fill the order form or can send mail at info@treatmentoptions4u.com. Patients can also send WhatsApp messages to +91 98738 10020. We will reply ASAP with the details of the Ibrutinib Tablet price as well as procurement procedure.

      Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

      NEWS / UPDATES

      1. Janssen-Cilag International Ltd, Electronic Medicines Compendium (EMC), [Revised on Jan 2021] [Accessed on 6th Jun 2021], https://www.medicines.org.uk/emc/files/pil.10040.pdf
      2. [Revised on Dec 2020] [Accessed on 6th Jun 2021], https://www.imbruvica.com/files/prescribing-information.pdf
      3. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
      4. Sapna Parmar, Khilna Patel, Javier Pinilla-Ibarz, Ibrutinib (Imbruvica): A Novel Targeted Therapy for Chronic Lymphocytic Leukemia, Drug Forecast, 2014, 39(7), https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103574/pdf/ptj3907483.pdf