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Treosulfan was approved for use in the European Union in June 2019.Two main studies showed that treosulfan is at least as effective as busulfan, another medicine used to prepare patients for haematopoietic stem cell transplantation.
- Generic Brand Name – Emtreo
- Innovator Brand Name – Trecondi
- API – Treosulfan
- Packaging – 1 Vial
- Strength – 5gm
- Manufacturer Name – Emcure Pharma Ltd.
What is treosulfan used for?
Treosulfan is an alkylating agent. It is used to prepare patients for bone marrow transplants (hematopoietic stem cell transplantation). The treosulfan injection is used before the blood stem cell transplantation in adult patients with cancer and non-cancerous disorders and children and adolescents aged older than 30 days with cancer.
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Get Access To Treosulfan Injection 5 gm
Facts of Medicines
HOW SUPPLIED/STORAGE AND HANDLING:
Care is exercised in the handling of EMTREO. Injection should not be open or broken. Emtreo Injection should be stored at room temperature, away from heat and direct light. Do not freeze it.
Most common adverse reactions in adults and children include infections, nausea (feeling sick), stomatitis (inflammation of the lining of the mouth), vomiting, diarrhea, and bellyache. Tiredness, low white blood cell counts with fever, high blood levels of bilirubin are also reported in adult patients, and rash also affects children.
The recommended dose of treosulfan injection is 10-14 g/m² body surface area administered by drip (infusion) into a vein over 2 hours for three days before the blood stem cell infusion. For adults, Emtreo injection is used together with fludarabine, and for children/adolescents, it is used along with fludarabine, and in most cases, together with thiotepa.
WARNINGS AND PRECAUTIONS
- Patients with treosulfan 5g injection should be monitored for blood cell counts frequently until recovery of the hematopoietic system.
- Concomitant use/application of live attenuated vaccines is not allowed.
- The treosulfan 5gm injection might impair fertility in men as well as women. Therefore, men must seek advice on cryo-conservation of sperm before treatment due to the probability of irreversible infertility.
- Sexually active men/women of childbearing potential have to use apt and effective contraception while up to 6 months following treatment.
- Use of treosulfan 5g injection is contraindicated during pregnancy.
- Breast-feeding should be discontinued during treosulfan injection treatment.
- Treosulfan injection has a moderate influence on the ability to drive as well as use machines.
FAQs – Medicine Questions
What is Treosulfan 5gm?
From which class of drug Treosulfan belongs?
How should Treosulfan be administered?
Where can I buy Treosulfan Injection?
You can buy Treosulfan Injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.
The buyer should check the existing law in their home country before importing the product.
What is the procedure to buy Treosulfan Injection?
Patients can simply fill the order form or can send mail at firstname.lastname@example.org. Patients can also send WhatsApp messages to +91 98738 10020. We will reply ASAP with the details of the Treosulfan Injection price as well as procurement procedure.
Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.
NEWS / UPDATES
- Medexus Inc., [Revised on 25th Jun 2021] [Accessed on 8th Dec 2021], https://d1io3yog0oux5.cloudfront.net/medexusinc/files/pages/medexusinc/db/795/description/Trecondyv+Product+Monograph.pdf
- Tilomed Laboratories Ltd, Electronic Medicines Compendium, [Revised on Feb 2021] [Accessed on 8th Dec 2021], https://www.medicines.org.uk/emc/files/pil.11187.pdf
- International agency for research on cancer; Treosulfan; PHARMACEUTICALS; NCBI Bookshelf; [Revised on 2012] [Accessed: 10/Apr/2021]; https://www.ncbi.nlm.nih.gov/books/NBK304322/#_NBK304322_pubdet_
- RA Hilger et al; Clinical pharmacokinetics of intravenous Treosulfan in patients with advanced solid tumors; [Revised on 1998] [Accessed: 10/Apr/2021] ; https://pubmed.ncbi.nlm.nih.gov/9654108/
- GP Breitbach; Treosulfan in the treatment of advanced ovarian cancer: a randomized co-operative multicentre phase-III study; [Revised on 2002] [Accessed:10/Apr/2021]; https://pubmed.ncbi.nlm.nih.gov/12530019/