Shreyaansh Lifesciences, Jaipur. India

Dexrazoxane for Injection
Dexrazoxane injection (Totect, Zinecard) is used to prevent or decrease thickening of the heart muscles caused by doxorubicin in women who are taking the medication to treat breast cancer that has spread to other parts of the body.

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Ribociclib-tablets Available Price In India UK Saudi Arabia

Ribociclib Tablets

  • Brand Name – Kryxana
  • API – Ribociclib
  • Packaging – 21 Tablets
  • Strength – 200 mg
  • Manufacturer Name – Novartis Pharma

What is ribociclib used for?

Ribociclib Tablet is a cyclin-dependent kinase inhibitor, indicated to use with the combination of the aromatase inhibitor to treat HR-Positive and HER2-Negative advanced as well as metastatic breast cancer. This FDA approved medication was developed by Novartis.

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    Dexrazoxane :- Uses & Approval

    Dexrazoxane has been used to protect the heart against the cardiotoxic side effects of chemotherapeutic drugs such as anthracyclines, such as daunorubicin or doxorubicin or other chemotherapeutic agents.

    The United States Food and Drug Administration has also approved a dexrazoxane for use as a treatment of extravasation resulting from IV anthracycline chemotherapy. Extravasation is an adverse event in which chemotherapies containing anthracylines leak out of the blood vessel and necrotize the surrounding tissue.

    On July 19, 2017, based on evaluation of the currently available data the European Commission issued an EU-wide legally binding decision to implement the recommendations of the Committee for Medicinal Products for Human Use (CHMP) on dexrazoxane and lifted its 2011-contraindication for primary prevention of anthracycline-induced cardiotoxicity with dexrazoxane in children and adolescents where high doses (≥ 300 mg/m3) of anthracyclines are anticipated.

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