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Pertuzumab Injection 420 mg
Pertuzumab Injection used to treat breast cancers that have too much of a protein (receptor) called HER2 on the surface of their cells. This is called HER2-positive breast cancer.

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Pertuzumab Injection was approved for medical use in the United States in 2002. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic medication.

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Pertuzumab Injection

  • Generic Brand Available – On Request
  • API – Pertuzumab
  • Packaging – Glass Bottle
  • Strength – 420 mg

What is Pertuzumab Injection used for?

 

  • Pertuzumab Injection (Perjeta) and trastuzumab are targeted therapy drugs used to treat breast cancer. They are usually given with chemotherapy.
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    Lucknow Speciality Pharma, Lucknow, India

    Lucnow Speciality Pharma is registered in Lucknow, India. Registration Number : AAKFL2122J1ZB Under GST Act
    Branch Offices in India : Lucknow | Agra | Jaipur | Varanasi | New Delhi

    2nd Floor, 203-A, Felix Square, Golf City, Gomti Nagar, Lucknow, Uttar Pradesh 226030

    Mobile :+91 97600 14849 / 9555306364
    WhatsApp :+91 97600 14849 / 9555306364

    info@lucknowpharma.com
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    Facts of Medicines

    Pertuzumab Injection 420 mg

    STORAGE AND HANDLING

    Pertuzumab Injection must be refrigerated at 2°C to 8°C (36°F to 46°F). Do not use the Pertuzumab Injection beyond the expiration date located on the carton and the vial.

    DOSAGE

     Pertuzumab injection comes as a solution (liquid) to be injected into a vein over a 30 to 60 minutes by a doctor or nurse in a hospital or medical facility. It is usually given every 3 weeks. The length of your treatment depends on how well your body responds to the medication and the side effects that you experience.

    Pertuzumab injection may cause serious or possibly life-threatening reactions that may occur while the medication is being given and for a period of time afterwards. Your doctor or nurse will watch you carefully while you receive each dose of pertuzumab injection, and for at least one hour after your first dose and thirty minutes after later doses. Tell your doctor or nurse right away if you experience any of the following symptoms during or shortly after your infusion: shortness of breath, wheezing or noisy breathing, hoarseness, difficulty swallowing, hives, rash, itching, fever, chills, tiredness, headache, weakness, vomiting, unusual taste in the mouth, or muscle pain.

    SIDE EFFECTS

    • The following clinically significant adverse reactions can occur with Pertuzumab Injection: Cardiovascular Toxicity, Myelosuppression, Hypersensitivity, Hypertension, Pancreatic Toxicity.

    WARNINGS AND PRECAUTIONS

    • Genetic testing should be indicated in order to detect whether a person is at higher risk of developing hypersensitivity.
    • Pertuzumab Injection may not be added as a single agent when antiretroviral regimens are changed because of loss of the virologic response.
    • Patients with liver disease should be watchful and cautious in order to Pertuzumab Injection because it can aggravate the condition.
    • In patients with Pertuzumab Injection, conditions like immune reconstitution inflammatory syndrome, a change in body fat as well as an increased risk of heart attack may occur.
    • Pertuzumab Injection is not recommended for use in infants who are under 3 months of age.
    • Cases like lactic acidosis and severe hepatomegaly with steatosis occurred with the use of nucleoside analogues.
    • Sometimes serious hypersensitivity reactions have been associated with Pertuzumab Injection.

    FAQs – Medicine Questions

    Pertuzumab Injection 420 mg
    What is pertuzumab injection?
    Pertuzumab injection is used along with trastuzumab (Herceptin) and docetaxel (Taxotere) to treat a certain type of breast cancer that has spread to other parts of the body.
    What is the difference between trastuzumab and pertuzumab?
    Pertuzumab is a fully humanized monoclonal antibody which binds to domain II of HER2, essential for dimerization [27, 59], while trastuzumab binds to domain IV. Pertuzumab efficiently inhibits ligand-induced HER2/HER3 dimerization, whereas trastuzumab has only a minor effect in the presence of a ligand.
    How do you administer pertuzumab?
    The recommended initial loading dose of pertuzumab is 840 mg administered as a 60 minute intravenous infusion, followed every 3 weeks thereafter by a maintenance dose of 420 mg administered over a period of 30 to 60 minutes.
    Where can I buy Pertuzumab Injection?

    You can buy Pertuzumab Injection Tablets from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

    The buyer should check the existing law in their home country before importing the product.

    What is the procedure to buy Pertuzumab Injection?

    Patients can simply fill the order form or can send mail at info@treatmentoptions4u.com. Patients can also send WhatsApp messages to +91 99292 77766 / 98738 10020   We will reply ASAP with the details of the Pertuzumab Injection price as well as procurement procedure.

    Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

    Is pertuzumab a chemotherapy?
    Pertuzumab is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “antineoplastic agent and a monoclonal antibody”. (For more detail, see “How Pertuzumab Works” below).

    NEWS / UPDATES

    1. Roche Products Ltd, Electronic medicines compendium (emc), [Revised on May 2021] [ Accessed on 3rd Dec 2021], https://www.medicines.org.uk/emc/files/pil.2993.pdf
    2. Genentech, Inc, US Food and Drug Administration, [Revised on June 2012] [ Accessed on 3rd Dec 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/125409lbl.pdf
    3. Komal Jhaveri, Francisco J Esteva; Pertuzumab in the treatment of HER2+ breast cancer; Journal of the National Comprehensive Cancer Network; Published on April 2014; Accessed on 03/12/2021; https://pubmed.ncbi.nlm.nih.gov/24717573/