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Cobimetinib Tablets 20 mg
Cobimetinib Tablets is used in combination with vemurafenib to treat melanoma (skin cancer) that has spread or that cannot be removed by surgery

Cobimetinib, sold under the brand name Cotellic, is an anti-cancer medication used in combination with vemurafenib (Zelboraf) alone or with both vemurafenib and atezolizumab (Tecentriq) to treat melanoma. Cobimetinib is a MEK inhibitor. Cobimetinib was approved for medical use in the United States in November 2015

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Cobimetinib Tablets

  • Innovator Brand Name – N/A
  • Generic Brand Available – Cotellic
  • API – Cobimetinib
  • Packaging – 63 Tablets
  • Strength – 20 mg

What is Cobimetinib Tablets used for?

Cobimetinib tablets are used in combination with vemurafenib to treat melanoma (skin cancer) that has spread or that cannot be removed by surgery.

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    Get Access To Cobimetinib Tablets 20 mg

    Shreyaansh Lifesciences, Jaipur. India

    Shreyaansh Lifesciences is registered in Jaipur, India. Registration Number : 08AEEFS9350K1ZI under GST Act. 
    Branch Offices in India : Jaipur | New Delhi

    SF-72-73 2ND FLOOR, Jaipur Electronic Market, Ridhi Sidhi Choraha, Jaipur, Rajasthan, 302018.

    +91 99292 77766

    Facts of Medicines

    Cobimetinib Tablets 20 mg

    INDICATIONS AND USAGE
    COTELLIC is a kinase inhibitor indicated for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with vemurafenib. Limitation of Use: COTELLIC is not indicated for treatment of patients with wild-type BRAF melanoma.

    DOSAGE AND ADMINISTRATION
    Confirm the presence of BRAF V600E or V600K mutation in tumor specimens prior to initiation of COTELLIC.  The recommended dose is 60 mg orally once daily for the first 21 days of each 28-day cycle until disease progression or unacceptable toxicity. Take COTELLIC with or without food.

    ADVERSE REACTIONS
    Most common adverse reactions for COTELLIC (≥20%) are diarrhea, photosensitivity reaction, nausea, pyrexia, and vomiting. The most common
    (≥5%) Grade 3-4 laboratory abnormalities are increased GGT, increased CPK, hypophosphatemia, increased ALT, lymphopen.

    WARNINGS AND PRECAUTIONS
     

    • New primary malignancies, cutaneous and non-cutaneous: Monitor patients for new malignancies prior to initiation of therapy, while on therapy, and for up to 6 months following the last dose of COTELLIC.
    • Hemorrhage: Major hemorrhagic events can occur with COTELLIC. Monitor for signs and symptoms of bleeding. 
    • Cardiomyopathy: The risk of cardiomyopathy is increased in patients receiving COTELLIC with vemurafenib compared with vemurafenib as a
      single agent. The safety of COTELLIC has not been established in patients with decreased left ventricular ejection fraction (LVEF). Evaluate LVEF
      before treatment, after one month of treatment, then every 3 months thereafter during treatment with COTELLIC.

    FAQs – Medicine Questions

    Cobimetinib Tablets 20 mg
    What is cobimetinib used for?
    Cobimetinib is used in combination with vemurafenib to treat melanoma (skin cancer) that has spread or that cannot be removed by surgery.
    Is Cobimetinib FDA approved?
    On November 10, the Food and Drug Administration (FDA) approved the use of cobimetinib (Cotellic™) in combination with vemurafenib (Zelboraf®) to treat patients with metastatic melanoma.
    What is vemurafenib and Cobimetinib?
    The combination of vemurafenib and cobimetinib interferes with abnormal BRAF signals to slow or stop the out-of-control cell growth: Vemurafenib blocks the signaling pathway of the V600E-mutated BRAF molecule. Cobimetinib blocks signaling from the V600E- or V600K-mutated BRAF molecule via the MEK molecule.
    Where can I buy Cobimetinib Tablets?

    You can buy Cobimetinib Tablets from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

    The buyer should check the existing law in their home country before importing the product.

    What is the procedure to buy Cobimetinib Tablets?

    Patients can simply fill the order form or can send mail at info@treatmentoptions4u.com. Patients can also send WhatsApp messages to +91 99292 77766 / 98738 10020   We will reply ASAP with the details of the Cobimetinib Tablets price as well as procurement procedure.

    Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

    What is Cotellic used for?

    COTELLIC is a prescription medicine that is used with the medicine ZELBORAF, to treat a type of skin cancer called melanoma that has spread to other parts of the body or cannot be removed by surgery, and that has a certain type of abnormal “BRAF” gene.

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