Biodronate (Pamidronate) Injection

Description

Description

This page contains brief details about the drug pamidronate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Pamidronate consists of the active substance Pamidronate. It is a medication that belongs to a class of drugs called bisphosphonates. It is used to treat high calcium levels in the blood, a condition known as hypercalcemia, which can be caused by cancer or other medical conditions. This helps to increase bone density and reduce the risk of fractures in people with osteoporosis (bone weakening) or other bone conditions. It works by slowing down the breakdown of bone tissue, which helps reduce the amount of calcium released into the bloodstream. The dosage and frequency of administration will depend on the individual’s medical condition and other factors such as age, weight, and overall health.

Pamidronate was first approved by the U.S. Food and Drug Administration (FDA) in 1991 for treating hypercalcemia of malignancy, a condition in which cancer cells release calcium into the bloodstream. Since then, pamidronate has also been approved for treating other conditions related to bone metabolisms, such as osteoporosis and Paget’s disease of bone.

Mechanism of Action of Pamidronate

Pamidronate belongs to a class of drugs called bisphosphonates, which inhibit the activity of osteoclasts. Osteoclasts are responsible for breaking down bone tissue, which releases calcium into the bloodstream. By inhibiting osteoclasts’ activity, it helps slow down the breakdown of bone tissue and reduce the amount of calcium released into the bloodstream.

Uses of Pamidronate

Pamidronate is a medication used to treat various bone-related conditions, including hypercalcemia, cancer-related bone diseases, osteoporosis, and Paget’s disease of bone. It is also used in treatment of breast cancer metastasis (spread) to bone and osteolytic lesion of multiple myeloma (a type of bone cancer).

Pamidronate Dosage available

Pamidronate is a medication that is administered by a healthcare professional, typically in a hospital or clinic setting. The medication is given as an intravenous (IV) injection by healthcare professional. The infusion typically takes several hours. You will be closely monitored during and after the infusion to ensure the medication works effectively and to watch for any side effects. The dosage and frequency of administration will depend on the condition being treated and your circumstances. Your healthcare provider will determine the appropriate dosage and schedule for you.