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Capecite (Capecitabine) Tablet
Generic brands for Capecitabine Injection Available in India Brand Name Capecite Generic Name Capecitabine Strength 500mg Manufacturer Abbott
Description
Description
This page contains brief details about the drug capecitabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Capecitabine is an anticancer drug that belongs to the category of medicines known as antimetabolite. It was approved in April 1998 to treat Metastatic colorectal cancer.
Mechanism of Action of Capecitabine
It gets converted into its active form called fluorouracil and interferes with cell signalling, ultimately preventing the multiplication of cancer cells. Capecitabine is prescribed alone and also in combination with other anticancer medications like Docetaxel and Oxaliplatin.
Uses of Capecitabine
Capecitabine has been developed as a first-line agent to treat advanced and metastatic colorectal cancer and also indicated as an adjunct treatment for stage III colon cancer after the failure of Irinotecan therapy. Capecitabine is also prescribed to treat breast cancer after the failure of taxane-based therapy.
Capecitabine
Dosage available
Capecitabine is available in the form of 500mg tablets. Swallow a tablet with water 30 minutes after food. If you have difficulty swallowing the tablet, seek help from a healthcare provider specialized in the usage of cytotoxic medications to crush or cut the tablet. The accurate dose will be calculated by your healthcare provider and the recommended dosing cycle is twice a day for 2 weeks followed by a 7-days rest period.
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References
- Morningside Healthcare Ltd, Electronic medicines compendium (emc), [ Revised on Feb 2021] [ Accessed on 9th March 2023], https://www.medicines.org.uk/emc/files/pil.11498.pdf
- Genentech USA, Inc, US Food and Drug Administration, [ Revised on March 2015] [ Accessed on 9th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020896s037lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 864.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1698.