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Chemoblast (Vinblastine) Injection
Generic brands for Vinblastine Injection Available in India Brand Name Chemoblast Generic Name Vinblastine Strength 10mg Manufacturer Neon Laboratories Ltd
Description
Description
This page contains brief details about the drug vinblastine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Vinblastine is an anticancer drug that belongs to the category of medicines known as mitotic inhibitors. It was approved by the U.S. FDA in the year 1962 to treat Hodgkin’s and non-Hodgkin’s lymphoma.
Mechanism of Action of Vinblastine
It works by disrupting the formation of microtubules in cells. Microtubules are structures that help to support and shape cells, as well as transport molecules within cells. In cancer cells, microtubules play a key role in cell division and growth. By interfering with microtubule formation, this drug disrupts the ability of cancer cells to divide and grow, ultimately leading to their death.
Uses of Vinblastine
Vinblastine is used to treat Hodgkin’s and non-Hodgkin’s lymphoma, testicular cancer, breast cancer, and kaposi’s sarcoma.
Vinblastine Dosage available
The medicine will be administered to you by a healthcare professional in a hospital setting. Vinblastine is given as an injection into a vein (intravenous infusion) over a period of 30 minutes, once a day for up to 5 days. The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.
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References
- Hospira UK Limited, Electronic medicines compendium (EMC), [Revised on Sept 2020][ Accessed on 4th April 2023], https://www.medicines.org.uk/emc/files/pil.1422.pdf
- DBL vinblastine injection – pfizer. Available at: https://labeling.pfizer.com/ShowLabeling.aspx?id=12288 [ Accessed on 4th April 2023].
- Vinblastine injection -NPS MedicineWise. Available at: https://www.nps.org.au/assets/medicines/aea96da5-9c46-482b-9add-a53300ff05d1.pdf [ Accessed on 4th April 2023].
- HY Yap; Vinblastine given as a continuous 5-day infusion in the treatment of refractory advanced breast cancer; Cancer Treatment Reports; Published on March 1980;[ Accessed on 4th April 2023]; https://pubmed.ncbi.nlm.nih.gov/7407762/
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.