Leuprosta Depot (Leuprolide Acetate) Injection

Generic brands for Leuprolide Acetate Injection Available in India Brand Name Leuprosta Depot Generic Name Leuprolide Acetate Strength 4mg, 11.25mg, 22.5mg Manufacturer Alkem Laboratories Ltd

Description

Description

This page contains brief details about the drug leuprolide acetate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Leuprolide Acetate is a gonadotropin-releasing hormone (GnRH) agonist approved for its medical use on 9th April 1985.

Mechanism of Action of Leuprolide Acetate

Leuprolide Acetate Injection is a biological agent that acts as hormonal drug therapy in cancer treatment. It comes under the class of Gonadotropin-releasing hormone (GnRH) agonist. It stimulates the luteinizing hormone and follicle-stimulating hormone of the pituitary gland, resulting in high estrogen in females and high testosterone and dihydrotestosterone in males. With continuous use, the levels of these hormones fall, and the organs which depend on these hormones become inactive. It is often administered in combination with other medications to alleviate pain symptoms.

Uses of Leuprolide Acetate

Leuprolide Acetate Injection has been developed to treat solid tumors by injecting it directly into the bloodstream. Leuprolide Acetate Injection has been approved to treat several conditions such as prostate cancer, endometriosis, uterine fibroids and other hormonal conditions.

Leuprolide Acetate Dosage available

Leuprolide acetate Injection is available in different doses.  This injection will be mostly administered by your doctor or nurse on your arm, thigh or abdomen after preparation. The site of injecting this medicine will be changed regularly. Your healthcare provider will administer this medicine once in three months.

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News/Updates

References

  1. AbbVie Inc., US Food & Drug Administration, [Revised on Feb 2021] [Accessed on 12th April 2023 ], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020011s042,019943s035lbl.pdf
  2. Dallas V. Swayzer; Valerie Gerriets, StatPearls [Internet], [Revised on 11th Jul 2022] [Accessed on 12th April 2023], https://www.ncbi.nlm.nih.gov/books/NBK551662/
  3. Takeda UK Limited, Electronic Medicines Compendium (EMC), [Revised on Jun 2022] [Accessed on 13th Aug 2022], https://www.medicines.org.uk/emc/files/pil.4651.pdf