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Soliqua Solostar (Insulin Glargine + Lixisenatide) Injection
Generic brands for Insulin Glargine + Lixisenatide Injection Available in India Brand Name Soliqua Solostar Generic Name Insulin Glargine + Lixisenatide Strength Manufacturer Sanofi India Ltd
Description
Description
This page contains brief details about the drug insulin glargine,lixisenatide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The FDA approved Insulin glargine, Lixisenatide for medical use on 21st, Nov 2016 for Type 2 diabetes.
A 2022 study evaluated the efficacy of Insulin Glargine and Lixisenatide in adults with type 2 diabetes. The study found that Insulin Glargine and Lixisenatide significantly improved glycemic control by reducing HbA1c levels without causing weight gain. Additionally, the study reported a low risk of hypoglycemia.
Mechanism of Action of Insulin Glargine + Lixisenatide
The Insulin glargine in the medicine, helps to lower the blood glucose level by replacing the insulin which is normally produced in our body. The Lixisenatide is an GLP-1 agonist, which stimulates the release of insulin during the hyperglycemia (high blood glucose level).
Uses of Insulin Glargine + Lixisenatide
Insulin glargine, Lixisenatide, is used to control blood sugar levels and elevate the production of insulin in the body. It also helps to slow down glucose absorption from foods. It aids in treating type 2 diabetes in adults and controls blood sugar when it becomes abnormal. If other medicines fail to treat or control high blood glucose levels, Insulin glargine, Lixisenatide can be given along with metformin and/or sodium-glucose co-transporter-2 (SGLT2) inhibitors.
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News/Updates
References
- Sanofi-Aventis Deutschland GmbH, European Medicines Agency (EMA), [Revised on 18 July 2024] [Accessed on 21 May 2024], Suliqua, INN-insulin glargine+lixisenatide (europa.eu)
- Sanofi-aventis, US Food and Drug Administration, FDA [Revised on July 2021] [Accessed on 21st May 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/208673s013lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Hormones and Hormones Antagonists, 13th edition, 2011, 871 & 877.
- Candido, R., Modugno, M., Larosa, M. et al. Effectiveness, Safety, and Appropriateness in the Use of the Fixed-Ratio Combination of Insulin Glargine and Lixisenatide in Type 2 Diabetes: The ENSURE Retrospective Real-World Study. Diabetes Ther 14, 77–92 (2023). https://doi.org/10.1007/s13300-022-01328-7