Vinozest (Vinorelbine) Injection

Generic brands for Vinorelbine Injection Available in India Brand Name Vinozest Generic Name Vinorelbine Strength 10mg, 50mg Manufacturer Zee Laboratories Ltd  

Description

Description

This page contains brief details about the drug vinorelbine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Vinorelbine is a chemotherapy medication that was approved to be used in 1994.

Mechanism of Action of Vinorelbine

Vinorelbine works by inhibiting the microtubule structures within the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth and multiplication of cancer cells.

Uses of Vinorelbine

Non-small cell lung cancer (NSCLC)

Breast cancer

Vinorelbine Dosage available

Vinorelbine is available as solution for infusion in two doses of 10mg and 50mg.

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News/Updates

References

  1. Pierre Fabre Limited, Electronic medicines compendium (EMC), [Revised on Nov 2022] [ Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.3912.pdf
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
  4. Pierre Fabre Medicament, US Food and Drug administration, [Revised on Jan 2022] [ Accessed on 1st Dec 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020388s037lbl.pdf
  5. Anna Capasso; Vinorelbine in Cancer therapy; Cancer Drug Targets; Published on July 2012; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/22594474/
  6. Ying-Chun Xu et al; A systematic review of vinorelbine for the treatment of breast cancer; The Breast Journal; Published on April 2013; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/23320984/