Akynzeo (Netupitant+Palonosetron) Capsule

Description

Description

This page contains brief details about the drug netupitant,palonosetron, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Netupitant, Palonosetron is an antiemetic drug that belongs to the category of medicines known as alkylating agents. It was approved by the FDA in July 2003 to treat Chemotherapy-induced nausea and vomiting.

Mechanism of Action of Netupitant+Palonosetron

It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. The chemotherapeutic trigger zone( CTZ) contains the receptor serotonin, when this CTZ is stimulated, vomiting occurs. Palonosetron prevents the signals from serotonin and helps to reduce the symptoms of nausea and vomiting.

Uses of Netupitant+Palonosetron

Netupitant, Palonosetron is an anti-emetic agent used to treat Postoperative nausea & vomiting. It is also used to treat Chemotherapy induced nausea & vomiting.

Netupitant+Palonosetron Dosage available

Netupitant,Palonosetron is a prescription drug available in tablet and injection form. The medicine will be administered to you by a healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Palonosetron Hydrochloride Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. If you are taking palonosetron as an oral tablet, it should be swallowed whole with a glass of water, with or without food, as directed by your healthcare provider.