Category: Antifungal Antibiotic

  • Isavuconazole

    Description

    This page contains brief details about the drug isavuconazole, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Isavuconazole was first approved by the U.S. FDA on March 6, 2015.

    Mechanism of Action of Isavuconazole

    Isavuconazole produces fungicidal action by disrupting the biosynthesis of ergosterol. Ergosterol is an essential component of the fungal cell membrane. Disruption of ergosterol leads to reduced structural integrity, cell membrane function and causes inhibition of fugal growth and replication, thereby causing cell death.

    Uses of Isavuconazole

    Isavuconazole is an azole antifungal medication used to treat Invasive Aspergillosis and Invasive Mucormycosis.

    Isavuconazole Dosage available

    Isavuconazole is to be administered as prescribed by your healthcare provider. It is administered by two ways.

    Isavuconazole capsule is administered either orally with or without food. Isavuconazole injection is administered as an infusion into the vein.

  • Liposomal Amphotericin B

    Description

    This page contains brief details about the drug liposomal amphotericin b, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Liposomal Amphotericin B is an antifungal antibiotic. FDA approved this medicine on 11th August 1997 for its medical use.

    Mechanism of Action of Liposomal Amphotericin B

    Liposomal Amphotericin B binds primarily to ergosterol in sensitive fungi cell membranes, causing membrane permeability changes that result in leakage of intracellular contents and cell death.

    Uses of Liposomal Amphotericin B

    It is used to treat fungal infections of one or more deep body organs. It is also used to treat suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells). It is also indicated to treat visceral leishmaniasis, a disease caused by a parasite in certain people.

    Liposomal Amphotericin B Dosage available A doctor or nurse in a hospital or clinic setting will give it to you. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.