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Category: Cancer
Peg L-Asparaginase
Description
This page contains brief details about the drug peg l-asparaginase, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects
Date of Approval
Peg-L-Asparaginase is a class of antitumor drug that belongs to the category of medicines known as enzymes known as hydrolases. It was approved on 30 June 2021 to treat Acute Lymphoblastic Leukaemia.
Mechanism of Action of Peg L-Asparaginase
Cancer cells need a substance called asparagine to survive. This Injection works by lowering the levels of asparagine in the body.
Uses of Peg L-Asparaginase
Peg-L-Asparaginase is used to treat Acute Lymphoblastic Leukaemia (a type of cancer of the white blood cells).
Peg L-Asparaginase Dosage available
It will be given to you by your health care professional. Do not self-administer. Your physician will decide the dose and duration of your treatment based on the disease severity and other factors.
Exemestane
Description
This page contains brief details about the drug exemestane, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Exemestane is an anticancer medication that was approved for its medical use on 21st October 1999.
Mechanism of Action of Exemestane
Exemestane is a steroidal agent that belongs to the class of third-generation aromatase inhibitors. The aromatase enzyme is responsible for producing the female sex hormone estrogen. Exemestane irreversibly inactivates the aromatase enzyme, lowers estrogen production, and ultimately slows the development of cancer cells.
Uses of Exemestane
Exemestane Tablet has been developed to treat early and advanced breast cancer in postmenopausal women who have taken Tamoxifen and other treatments before.
Exemestane Dosage available
Exemestane is available as a tablet in a dose of 25mg. Take Exemestane Tablet once a day after food.
Enzalutamide
Description
This page contains brief details about the drug enzalutamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Enzalutamide is an anticancer drug that belongs to the category of medicines known as antimetabolite. It was approved by the U.S. FDA on 31st of August 2012 to treat Prostate cancer.
Mechanism of Action of Enzalutamide
It works by inhibiting the active form of testosterone, called dihydrotestosterone. It selectively blocks the androgen receptors and disrupts the translocation of signals from the receptor to the cell. Thus, the androgen hormone does not bind to the androgen receptors and these androgen receptors do not interact with DNA. This blocks the functioning of cancer cells and reduces its multiplication.
Uses of Enzalutamide
Enzalutamide is prescribed to treat metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC).
Enzalutamide Dosage available
Enzalutamide is to be administered orally. This medication is to be swallowed as whole with water, without cutting, crushing or chewing. It can be taken with or without food.
Cyclosporine
Description
This page contains brief details about the drug cyclosporine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Cyclosporine is an immunosuppressant which was approved for its medical use on 1983.
Mechanism of Action of Cyclosporine
Cyclosporine is an immunosuppressant which prevents organ rejection in organ transplantation. It is classified as an immunosuppressant belonging to the category of Calcineurin inhibitors. Cyclosporine works inhibiting cytochrome P450 3A4, P-glycoprotein and interleukins to suppress the cell mediated immune response. Cyclosporine is often prescribed along with other immunosuppressants like azathioprine and mycophenolate mofetil.
Uses of Cyclosporine
Cyclosporine has been developed to prevent organ rejection in adult and pediatric patients receiving an allogeneic transplant of the liver, kidney, heart, or lung. it is indicated for It is also prescribed to treat rheumatoid arthritis for patients who have not responded adequately to methotrexate.
Cyclosporine Dosage available
Cyclosporine is available in the form of capsule, injection and oral solution. Cyclosporine Capsule is available in the doses 25mg, 50mg and 100mg. Your healthcare provider will administer Cyclosporine 50mg Injection if you are unable to tolerate oral capsule or suspension. Your healthcare provider will prescribe the accurate dose based on the organ transplanted, body weight and health condition.
Apalutamide
Description
This page contains brief details about the drug apalutamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Apalutamide is an anticancer drug in the androgen receptor inhibitors class of medications. The FDA approved the medicine for its medical use on September 17, 2019.
Mechanism of Action of Apalutamide
Apalutamide is a selective androgen receptor (AR) inhibitor that binds directly to the androgen receptor binding domain. It inhibits protein transportation in the nucleus, DNA binding, and AR-mediated transcription. Treatment with Apalutamide reduces cancer cell growth and increases cell death, resulting in effective anticancer activity.
Uses of Apalutamide
It is indicated for treating patients with certain types of prostate cancer whose cancer has spread to other parts of the body and still responds to a medical or surgical treatment that lowers testosterone (male reproductive hormone) or whose cancer has not spread to other parts of the body and no longer responds to a medical or surgical treatment that lowers testosterone.
Apalutamide Dosage available
Apalutamide is an orally administered drug. Take medicine as informed by your physician. It is generally taken with or without food once a day. Take the tablet at around the same time every day. Swallow the tablets whole; do not split, chew, or crush them. Do not stop taking Apalutamide without talking to your doctor.
Dasatinib
Description
This page contains brief details about the drug dasatinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Dasatinib is an anticancer agent which was approved for its medical use on 28th June 2006.
Mechanism of Action of Dasatinib
Dasatinib Tablet is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a tyrosine kinase inhibitor. The BCR ABL tyrosine kinase enzymes are responsible for the uncontrolled generation of white blood cells in leukemia. Dasatinib binds to both active and inactive sites of BCR ABL tyrosine kinase enzyme to inhibit the uncontrolled growth of white blood cells.
Uses of Dasatinib
Dasatinib Tablet has been developed to treat Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia in adults, adolescents and children who have not benefitted from previous therapies. It is also approved for treating chronic myeloid leukemia.
Dasatinib Dosage available
The recommended starting dose for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia is 140 mg per day. The ideal dose for children is calculated based on their body weight.
Dasatinib is available as a tablet in doses 20mg, 50mg, 70mg, and 100mg. It is advisable to take the tablets at the same time each day. Swallow them whole with some water and do not crush, cut or chew them.
Paclitaxel
Description
This page contains brief details about the drug paclitaxel, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Paclitaxel is a chemotherapeutic anticancer treatment drug which was approved for its medical use on December 1992.
Mechanism of Action of Paclitaxel
Paclitaxel is a chemotherapeutic agent that belongs to the category of medications called microtubule inhibitors. microtubules are structures that aid in the growth and development of cancer cells. Paclitaxel works by inhibiting these structures, ultimately stopping the multiplication of cancer cells. Paclitaxel is prescribed alone and also in combination with other anticancer medications.
Uses of Paclitaxel
Paclitaxel has been developed to treat certain forms of breast cancer, ovarian cancer, non-small cell lung cancer and AIDS-induced Kaposis sarcoma in patients who have not responded well to previous anticancer therapies.
Paclitaxel Dosage available
Paclitaxel is available in the form of injection in the doses 30mg, 100mg, 260mg and 300mg. Your healthcare provider will calculate the ideal dose according to your condition and administer it as an intravenous infusion after dilution.
Afatinib Dimaleate
Description
This page contains brief details about the drug afatinib dimaleate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Afatinib Dimaleate is an anticancer medicine was approved by the US Food and Drug Administration (FDA) on July 12, 2013, to treat patients with non-small cell lung cancer (NSCLC) whose tumors have certain (non-resistant) abnormal epidermal growth factor receptor (EGFR) genes and patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy.
Mechanism of Action of Afatinib Dimaleate
It functions by inhibiting the ErbB family of proteins, which includes EGFR (also known as the epidermal growth factor receptor, or ErbB1, ErbB2, ErbB3, and ErbB4) and HER2. Changes in the genes that create these proteins can have an impact on how cancer cells multiply and disseminate. Through the inhibition of these proteins and its activities, this medication can prevent the growth and proliferation of cancer cells and can help to slow or stop the progression of cancer.
Uses of Afatinib Dimaleate
Afatinib dimaleate is used to treat certain types of cancer, including non-small cell lung cancer with specific EGFR mutations.
Afatinib Dimaleate Dosage available
Afatinib dimaleate is an oral medication that is usually taken once a day, at approximately the same time each day, before food. If you have already eaten, wait at least 3 hours before taking this medicine.
It should be taken as prescribed by a doctor. These tablets should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect how the medication is absorbed and decrease its effectiveness. Take the missed dose as soon as you recall if your next planned dose is more than eight hours away. You should not take a double dose to make up for the second dose.
Tacrolimus
Description
This page contains brief details about the drug tacrolimus, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Tacrolimus is an immunosuppressant that was approved for its medical use on 8th April 1994.
Mechanism of Action of Tacrolimus
Tacrolimus is an immunosuppressant that prevents organ rejection in organ transplantation. It is classified as an immunosuppressant belonging to the category of Calcineurin inhibitors. Tacrolimus works by binding to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response. Tacrolimus is often prescribed along with other immunosuppressants like azathioprine and mycophenolate mofetil.
Uses of Tacrolimus
Tacrolimus has been developed to prevent organ rejection in adult and pediatric patients receiving an allogeneic transplant of the liver, kidney, heart, or lung.
Tacrolimus Dosage available Tacrolimus is available in the form of capsules, injections, oral suspensions, and ointments. Tacrolimus Capsule is available in doses 0.5mg, 1mg, and 5mg. your healthcare provider will administer Tacrolimus Injection (5mg/ml) if you are unable to tolerate an oral capsule or suspension. Your healthcare provider will prescribe the accurate dose based on the organ transplanted, body weight, and health condition. Patients diagnosed with cystic fibrosis might require higher doses.
Brentuximab Vedotin
Description
This page contains brief details about the drug brentuximab vedotin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The Brentuximab vedotin is medically approved for the treatment of Hodgkin lymphoma, cutaneous T-cell lymphoma and systemic Anaplastic Large Cell Lymphoma.
Mechanism of Action of Brentuximab Vedotin
Brentuximab vedotin consists of an antibody targeting CD30, a protein found on the surface of cancer cells, and a chemotherapy drug attached to the antibody. The antibody delivers the chemotherapy directly to the cancer cells, minimizing damage to healthy cells.
Uses of Brentuximab Vedotin
Brentuximab vedotin is used to treat various cancers, including classical Hodgkin lymphoma (both newly diagnosed and relapsed), systemic anaplastic large cell lymphoma, primary cutaneous anaplastic large cell lymphoma, cutaneous T-cell lymphoma, and CD30-expressing mycosis fungoides, all in combination with other therapies.
Brentuximab Vedotin Dosage available
Brentuximab vedotin can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.