Category: Diabetes

  • Dapagliflozin+Metformin

    Description

    This page contains brief details about the drug dapagliflozin,metformin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Dapagliflozin + Metformin is an anti-diabetic drug. Dapagliflozin belongs to the group of medications called sodium-glucose co-transporter. Metformin belongs to the class of medications called biguanides. FDA approved this medicine on October 30, 2014, for its medical use.

    Mechanism of Action of Dapagliflozin+Metformin

    Dapagliflozin reduces glucose reabsorption and lowers the renal threshold for glucose. It works by removing excess sugar from your body via your urine and lowering the sugar in your blood. Metformin primarily decreases hepatic glucose production and decreases intestinal absorption of glucose. It works mainly by inhibiting glucose production in the liver.

    Uses of Dapagliflozin+Metformin

    Dapagliflozin + Metformin is available as a tablet.  It treats type 2 diabetes mellitus in patients aged 18 years and older. This combination of medicines is taken by mouth (orally).

    Dapagliflozin+Metformin Dosage available

    It is an orally available prescription drug. Your doctor will decide the dose and duration of dapagliflozin + metformin based on the blood sugar and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time with food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

  • Dulaglutide

    Description

    This page contains brief details about the drug dulaglutide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Dulaglutide contains active components as dulaglutide. It is a medication that is used to treat type 2 diabetes. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Dulaglutide works by mimicking the action of a hormone called glucagon-like peptide-1 (GLP-1) in the body. It is typically used in combination with other diabetes medications, such as metformin or sulfonylureas, when diet and exercise alone are not sufficient to control blood sugar levels. This medication improves glycemic control and helps prevent hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). Many people with type 2 diabetes struggle with weight management. This medication has been shown to promote weight loss or maintenance in some individuals. This can benefit overall health and contribute to better diabetes management. It received FDA approval on September 17, 2014, for treating type 2 diabetes.

    Mechanism of Action of Dulaglutide

    Dulaglutide, a GLP-1 receptor agonist, improves glycemic control in individuals with type 2 diabetes by stimulating insulin secretion, suppressing glucagon release (a hormone that prevents excessive glucose production by the liver.), and slowing gastric emptying. These actions work together to lower blood sugar levels, promote weight loss or weight maintenance, and reduce appetite. By addressing multiple aspects of diabetes management, this medication offers a comprehensive therapeutic effect for individuals with type 2 diabetes.

    Uses of Dulaglutide

    Dulaglutide is a medication approved for the management of type 2 diabetes.

    Dulaglutide Dosage available

    Dulaglutide is typically administered by a healthcare professional once in a week. It is usually given as an injection. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.

  • Semaglutide

    Description

    This page contains brief details about the drug semaglutide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Semaglutide was initially approved by the U.S. Food and Drug Administration (FDA) on December 5, 2017, for treating type 2 diabetes. Since then, it has also received additional approvals for its use in chronic weight management.

    Mechanism of Action of Semaglutide

    Semaglutide, a GLP-1 receptor agonist, exerts its therapeutic effects by mimicking the action of the naturally occurring hormone GLP-1. In diabetes management, this medication enhances insulin secretion, inhibits glucagon release, slows gastric emptying, and decreases hepatic glucose production. This medication effect leads to improved glycemic control and reduced HbA1c levels. Additionally, this medication promotes weight loss through increased satiety, decreased food intake, and modulation of gastric function. It has also demonstrated cardiovascular benefits, including potentially reducing major cardiovascular events.

    Uses of Semaglutide

    rSemaglutide is used to improve blood sugar control in type 2 diabetes and aid in weight management in individuals with obesity or overweight.

    Semaglutide Dosage available

    Semaglutide is typically administered as a subcutaneous injection at a convenient time once a week, on the same day each week. The injection can be given in the abdomen, thigh, or upper arm. These medication pens come with clear instructions on how to load the needle, dial the dose, and administer the injection. After injecting, dispose of the needle safely in a sharps container. Regular monitoring and follow-up with your healthcare provider are important to assess your progress and make any necessary adjustments to your treatment plan.

  • Desmopressin

    Description

    This page contains brief details about the drug desmopressin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Desmopressin was first approved by the U.S. Food and Drug Administration (FDA) for medical use on November 1, 1978.

    Mechanism of Action of Desmopressin

    Desmopressin is a medication that mimics the action of the hormone vasopressin in the body. Its therapeutic effect primarily focuses on regulating water balance and reducing excessive urine production. By increasing water reabsorption in the kidneys, it helps alleviate symptoms of conditions such as central diabetes insipidus and bedwetting (nocturnal enuresis). It can also aid in treating mild to moderate von Willebrand disease by promoting the release of von Willebrand factor, a clotting protein.

    Uses of Desmopressin

    Desmopressin treats conditions such as diabetes insipidus, bedwetting (nocturnal enuresis), and von Willebrand disease.

    Desmopressin Dosage available Desmopressin can be administered orally in tablet form, as a nasal spray, or through injection. The specific usage instructions may vary depending on the condition being treated and the form of the medication. Oral tablets are typically taken with water, as directed by the healthcare provider. The nasal spray is administered by spraying into the nostrils, alternating nostrils with each dose. A healthcare professional usually gives injections under the skin or into a vein.

  • Insulin Glargine + Lixisenatide

    Description

    This page contains brief details about the drug insulin glargine,lixisenatide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    The FDA approved Insulin glargine, Lixisenatide for medical use on 21st, Nov 2016 for Type 2 diabetes.

    A 2022 study evaluated the efficacy of Insulin Glargine and Lixisenatide in adults with type 2 diabetes. The study found that Insulin Glargine and Lixisenatide significantly improved glycemic control by reducing HbA1c levels without causing weight gain. Additionally, the study reported a low risk of hypoglycemia.

    Mechanism of Action of Insulin Glargine + Lixisenatide

    The Insulin glargine in the medicine, helps to lower the blood glucose level by replacing the insulin which is normally produced in our body.  The Lixisenatide is an GLP-1 agonist, which stimulates the release of insulin during the hyperglycemia (high blood glucose level).

    Uses of Insulin Glargine + Lixisenatide

    Insulin glargine, Lixisenatide, is used to control blood sugar levels and elevate the production of insulin in the body. It also helps to slow down glucose absorption from foods. It aids in treating type 2 diabetes in adults and controls blood sugar when it becomes abnormal. If other medicines fail to treat or control high blood glucose levels, Insulin glargine, Lixisenatide can be given along with metformin and/or sodium-glucose co-transporter-2 (SGLT2) inhibitors.

    Insulin Glargine + Lixisenatide Dosage available Insulin glargine, Lixisenatide, is available as an injection for subcutaneous use to be administered by your healthcare provider. Your doctor will decide the most suitable dosage for your case according to your age and physical circumstances.

  • Dapagliflozin

    Description

    This page contains brief details about the drug dapagliflozin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Dapagliflozin is an anti-diabetic drug. It belongs to the group of medications called sodium-glucose co-transporter. FDA approved this medicine on January 8, 2014, for its medical use.

    Mechanism of Action of Dapagliflozin

    Dapagliflozin reduces glucose reabsorption and lowers the renal threshold for glucose. It mainly works by removing excess sugar from your body via your urine and lowering the sugar in your blood.

    Uses of Dapagliflozin

    Dapagliflozin is available as a tablet. It treats type 2 diabetes mellitus in patients above 18 years and older.

    Dapagliflozin Dosage available

    Take the Dapagliflozin as advised by your physician. Do not chew or break the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.