Category: Germ Cell

Description

This page contains brief details about the drug ifosfamide,mesna, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Ifosfamide, Mesna are alkylating agents and hemorrhagic cystitis inhibitors which was approved for its medical use in the year 1998.

Mechanism of Action of Ifosfamide With Mesna

These two combinations together work by damaging the DNA in cancer cells, which leads to cell death and slows the growth and spread of cancer. Mostly, this involves the formation of reactive metabolites in the liver, which are then transported to cancer cells in the body. These metabolites react with the DNA in the cancer cells, causing cross-links and breaks in the DNA strands. This interferes with the replication and transcription of DNA, leading to cell death.

Uses of Ifosfamide With Mesna

Ifosfamide, Mesna are indicated for the treatment of bladder inflammation, hemorrhagic cystitis and cancers in the soft tissues, germ cell, pancreas and cervix.

Ifosfamide With Mesna Dosage available

It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. Ifosfamide, Mesna is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors. Your doctor will give you certain medications to lessen the chance of getting side effects from the  Ifosfamide, Mesna treatment.