Category: Heart Attack and Stroke

  • Spironolactone

    Description

    This page contains brief details about the drug spironolactone, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    The U.S. FDA approved spironolactone on 08/20/2001, to treat heart failure, hypertension and hypokalemia.

    Mechanism of Action of Spironolactone

    This medication consists of spironolactone which is a potassium baring diuretic. This medication works by lowering the blood pressure by removing the excess of water and electrolyte from the body and maintains the balance without reducing the potassium level in the body.

    Uses of Spironolactone

    This medication is used in the treatment of heart failure and in hypertension (patient with high blood pressure). It is used to treat low potassium levels in the body which is otherwise known as hypokalemia and reduces the swelling (edema in the body).

    Spironolactone Dosage available Spironolactone is available as a 5mg, 10mg, 20mg, 25mg, 50mg and 100mg tablet which can be consumed orally with food. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

  • Rivaroxaban

    Description

    This page contains brief details about the drug rivaroxaban, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Rivaroxaban is an anticoagulant medication that was approved for medical use on 1st July 2011.

    Mechanism of Action of Rivaroxaban

    Rivaroxaban Tablet is an anticoagulant medication belonging to the class of selective direct Factor Xa inhibitors. Rivaroxaban binds and forms a complex with Factor Xa.  Factor Xa is a natural substance in the body that is responsible for the formation of blood clots. Rivaroxaban is prescribed alone or in combination with low-dose aspirin.

    Uses of Rivaroxaban

    Rivaroxaban Tablet has been developed to treat venous thromboembolism and its symptoms in adults and pediatric patients older than one month of age. It also prevents the occurrence of stroke, and blood clots in patients with acute critical illness, hospitalized patients, and in people with severe movement restriction. Rivaroxaban reduces the risk of a heart attack in patients diagnosed with coronary artery disease and atrial fibrillation.

    Rivaroxaban Dosage available

    Rivaroxaban is available as film-coated tablets in doses of 2.5mg, 10mg, 15mg, and 20mg. The accurate dose and frequency vary according to age and medical condition.

  • Rosuvastatin

    Description

    This page contains brief details about the drug rosuvastatin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    The U.S. FDA-approved Rosuvastatin for hypertension (high blood pressure) and cardiovascular disease on August 13, 2003. It belongs to the category of medicines called statins and fibric acid derivatives.

    Mechanism of Action of Rosuvastatin

    Rosuvastatin works by reducing Low-density lipoprotein (LDL) levels. It works by slowing down the production of cholesterol, thereby lowering blood cholesterol levels.

    Uses of Rosuvastatin

    Rosuvastatin treats high cholesterol and prevents heart attacks and strokes. It is advised to take a low-cholesterol diet and exercise regularly while taking this medication.

    Rosuvastatin Dosage available

    Take the Rosuvastatin tablet as your physician advises. Take medicine at the same time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

  • Cyclosporine

    Description

    This page contains brief details about the drug cyclosporine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Cyclosporine is an immunosuppressant which was approved for its medical use on 1983.

    Mechanism of Action of Cyclosporine

    Cyclosporine is an immunosuppressant which prevents organ rejection in organ transplantation. It is classified as an immunosuppressant belonging to the category of Calcineurin inhibitors. Cyclosporine works inhibiting cytochrome P450 3A4, P-glycoprotein and interleukins to suppress the cell mediated immune response. Cyclosporine is often prescribed along with other immunosuppressants like azathioprine and mycophenolate mofetil.

    Uses of Cyclosporine

    Cyclosporine has been developed to prevent organ rejection in adult and pediatric patients receiving an allogeneic transplant of the liver, kidney, heart, or lung. it is indicated for It is also prescribed to treat rheumatoid arthritis for patients who have not responded adequately to methotrexate.

    Cyclosporine Dosage available

    Cyclosporine is available in the form of capsule, injection and oral solution. Cyclosporine Capsule is available in the doses 25mg, 50mg and 100mg. Your healthcare provider will administer Cyclosporine 50mg Injection if you are unable to tolerate oral capsule or suspension. Your healthcare provider will prescribe the accurate dose based on the organ transplanted, body weight and health condition.

  • Tirofiban Hcl

    Description

    This page contains brief details about the drug tirofiban hcl, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Tirofiban hydrochloride (HCl) was initially approved by the U.S. Food and Drug Administration (FDA) on June 3, 1998.

    Mechanism of Action of Tirofiban Hcl

    Tirofiban hydrochloride (HCl)works by inhibiting the glycoprotein IIb/IIIa receptor on the surface of platelets. This receptor plays a crucial role in platelet aggregation and clot formation. By blocking this receptor, tirofiban helps prevent the formation of blood clots.

    Uses of Tirofiban Hcl

    Tirofiban hydrochloride (HCl) is an antiplatelet medication with multiple clinical applications. Its primary uses include managing acute coronary syndromes (ACS), encompassing unstable angina and non-ST-segment elevation myocardial infarction (NSTEMI), by reducing the risk of coronary artery clot formation. During percutaneous coronary interventions (PCI) like angioplasty and stent placement, it prevents platelet aggregation and clot formation at the intervention site. Additionally, it is occasionally considered for managing thrombocytopenia, investigated for ischemic stroke cases, used in some coronary artery bypass grafting (CABG) procedures to minimize graft occlusion risk, and employed adjunctively in high-risk patients prone to clot formation.

    Tirofiban Hcl Dosage available

    Tirofiban hydrochloride (HCl) is typically administered intravenously (IV), giving it directly into a vein. It is usually administered in a healthcare setting, such as a hospital, where medical professionals can closely monitor the patient.

  • Tacrolimus

    Description

    This page contains brief details about the drug tacrolimus, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Tacrolimus is an immunosuppressant that was approved for its medical use on 8th April 1994.

    Mechanism of Action of Tacrolimus

    Tacrolimus is an immunosuppressant that prevents organ rejection in organ transplantation. It is classified as an immunosuppressant belonging to the category of Calcineurin inhibitors. Tacrolimus works by binding to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response. Tacrolimus is often prescribed along with other immunosuppressants like azathioprine and mycophenolate mofetil.

    Uses of Tacrolimus

    Tacrolimus has been developed to prevent organ rejection in adult and pediatric patients receiving an allogeneic transplant of the liver, kidney, heart, or lung.

    Tacrolimus Dosage available Tacrolimus is available in the form of capsules, injections, oral suspensions, and ointments. Tacrolimus Capsule is available in doses 0.5mg, 1mg, and 5mg. your healthcare provider will administer Tacrolimus Injection (5mg/ml) if you are unable to tolerate an oral capsule or suspension. Your healthcare provider will prescribe the accurate dose based on the organ transplanted, body weight, and health condition. Patients diagnosed with cystic fibrosis might require higher doses.