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Category: Non-Small Cell Lung Cancer (NSCLC)
Paclitaxel
Description
This page contains brief details about the drug paclitaxel, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Paclitaxel is a chemotherapeutic anticancer treatment drug which was approved for its medical use on December 1992.
Mechanism of Action of Paclitaxel
Paclitaxel is a chemotherapeutic agent that belongs to the category of medications called microtubule inhibitors. microtubules are structures that aid in the growth and development of cancer cells. Paclitaxel works by inhibiting these structures, ultimately stopping the multiplication of cancer cells. Paclitaxel is prescribed alone and also in combination with other anticancer medications.
Uses of Paclitaxel
Paclitaxel has been developed to treat certain forms of breast cancer, ovarian cancer, non-small cell lung cancer and AIDS-induced Kaposis sarcoma in patients who have not responded well to previous anticancer therapies.
Paclitaxel Dosage available
Paclitaxel is available in the form of injection in the doses 30mg, 100mg, 260mg and 300mg. Your healthcare provider will calculate the ideal dose according to your condition and administer it as an intravenous infusion after dilution.
Afatinib Dimaleate
Description
This page contains brief details about the drug afatinib dimaleate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Afatinib Dimaleate is an anticancer medicine was approved by the US Food and Drug Administration (FDA) on July 12, 2013, to treat patients with non-small cell lung cancer (NSCLC) whose tumors have certain (non-resistant) abnormal epidermal growth factor receptor (EGFR) genes and patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy.
Mechanism of Action of Afatinib Dimaleate
It functions by inhibiting the ErbB family of proteins, which includes EGFR (also known as the epidermal growth factor receptor, or ErbB1, ErbB2, ErbB3, and ErbB4) and HER2. Changes in the genes that create these proteins can have an impact on how cancer cells multiply and disseminate. Through the inhibition of these proteins and its activities, this medication can prevent the growth and proliferation of cancer cells and can help to slow or stop the progression of cancer.
Uses of Afatinib Dimaleate
Afatinib dimaleate is used to treat certain types of cancer, including non-small cell lung cancer with specific EGFR mutations.
Afatinib Dimaleate Dosage available
Afatinib dimaleate is an oral medication that is usually taken once a day, at approximately the same time each day, before food. If you have already eaten, wait at least 3 hours before taking this medicine.
It should be taken as prescribed by a doctor. These tablets should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect how the medication is absorbed and decrease its effectiveness. Take the missed dose as soon as you recall if your next planned dose is more than eight hours away. You should not take a double dose to make up for the second dose.
Erlotinib
25MG; 100MG; 150MG Tablets Geftinat
Gefitinib brought a new lease of life to the treatment of Non-Small Cell Lung Cancer (NSCLC), the first targeted therapy for NSCLC. Gefitinib spells better survival in EGFR mutated patients, and a good tolerability combined with improved quality of life has been a highlight. GEFTINAT was the first generic brand to be introduced in 2004 at a fractional price of the innovator when the market was grappling between the high priced gefitinib and conventional cytotoxics. The brand not only became a strong pillar for the company but also for the patients.
With many such novel products NATCO continues to be the torch bearer of the Indian oncology market.