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Category: Skin
Dalbavancin
Description
This page contains brief details about the drug dalbavancin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA (food drug and administration) approved dalbavancin in may 23, 2014, is used to treat bacterial infection.
Mechanism of Action of Dalbavancin
Dalbavancin acts by inhibiting the synthesis of cell walls in bacteria by binding with the peptidoglycan of the bacteria. It is involved in bactericidal activity. It is the reason that the drug is effective against gram-positive bacteria (which have thick peptidoglycan) compared to gram-negative bacteria.
Uses of Dalbavancin
Dalbavancin is used to treat bacterial infections in adults and children who are three months old. It is also used to treat skin infections.
Dalbavancin Dosage available
Dalbavancin is available as an injection form. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Daptomycin
Description
This page contains brief details about the drug daptomycin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Daptomycin received its initial approval from the U.S. Food and Drug Administration (FDA) on September 1, 2003. It was first approved under the brand name Cubicin
Mechanism of Action of Daptomycin
Daptomycin’s mechanism of action involves disrupting the bacterial cell membrane. It binds to the bacterial cell surface, leading to rapid depolarization of the cell membrane, resulting in the leakage of cellular contents and ultimately causing bacterial cell death. By targeting the cell membrane, this medication is effective against many gram-positive bacteria, including MRSA and VRE, and is less likely to promote rapid resistance development.
Uses of Daptomycin
Daptomycin treats complicated skin and skin structure infections (cSSSI) and bloodstream infections caused by certain gram-positive bacteria, including vancomycin-resistant enterococcus (MRSA) and methicillin-resistant staphylococcus VRE.
Daptomycin Dosage available
Daptomycin is administered intravenously (IV) by a healthcare professional. The lyophilized powder is reconstituted with sterile water to prepare the solution for IV infusion. The recommended dosage and infusion rate vary based on the type and severity of the infection, as well as the patient’s weight and kidney function. This medication is usually given once daily.
Ampicillin, Sulbactam
Description
This page contains brief details about the drug ampicillin,sulbactam, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Ampicillin and Sulbactam is a combination antibiotic medication that contains two active ingredients, ampicillin and Sulbactam. It has been used for many years and has well-established safety profiles. They have been extensively studied and are considered safe and effective when prescribed. It is used in the treatment of various bacterial infections. Ampicillin is a penicillin-type antibiotic that works by inhibiting the growth of bacteria. It is effective against both Gram-positive and Gram-negative organisms. Sulbactam is a beta-lactamase inhibitor. Beta-lactamases are enzymes some bacteria produce that can break down certain antibiotics, including penicillins. Combining Sulbactam with ampicillin makes the medication more effective against bacteria that produce beta-lactamases. It received initial FDA approval for use in the United States on October 29, 1986.
Mechanism of Action of Ampicillin, Sulbactam
Ampicillin is a penicillin-type antibiotic that belongs to the beta-lactam class. It inhibits the synthesis of bacterial cell walls. Bacterial cell walls are essential for their survival and protection, and without a functional cell wall, bacteria cannot maintain their structure and integrity. Ampicillin interferes with the enzymes involved in synthesizing the bacterial cell wall, leading to its weakening and eventual lysis (breakdown). Sulbactam is a beta-lactamase inhibitor. Beta-lactamase is an enzyme certain bacteria produce to break down and inactivate beta-lactam antibiotics, including penicillins. Combining sulbactam with ampicillin makes the medication effective against bacteria that produce beta-lactamases. Sulbactam inhibits the action of these enzymes, preventing them from degrading ampicillin. This allows ampicillin to remain active and exert its antibacterial effect.
Uses of Ampicillin, Sulbactam
The combination of ampicillin and sulbactam is often used to treat various infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and gynecological infections. It is also sometimes used as empiric therapy for suspected mixed infections or when the specific bacteria causing the infection are unknown.
Ampicillin, Sulbactam Dosage available Ampicillin and Sulbactam is typically administered by a healthcare professional. It is usually given intravenously (IV) as an infusion or injection. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.