Category: Soft Tissue Infections

  • Teicoplanin

    Description

    This page contains brief details about the drug teicoplanin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Teicoplanin is an antibiotic that belongs to the class of medications called semisynthetic glycopeptide. The FDA approved this medicine for its use on 24 May 2018. FDA did not approve it for use in the USA.

    Mechanism of Action of Teicoplanin

    The cell wall of gram-positive bacteria is entirely made of peptidoglycan, which is necessary for cell wall synthesis. Teicoplanin interferes with the cell-wall biosynthesis of bacteria by binding to specific residues and inhibiting the polymer membrane. It works by killing the bacteria which can cause serious infections.

    Uses of Teicoplanin

    It is used in adults and children to treat bacterial infections of soft tissues, lungs, urinary tract, endocarditis, abdominal wall, blood, bones, and joints. It works by killing the bacteria that cause infections in the body.

    Teicoplanin Dosage available

    Teicoplanin is available as an injection. It will be given to you by a doctor or other healthcare professional. It will be given as an intravenous injection (into a vein) or intramuscular (into a muscle). It can also be given as an infusion through a drip into a vein. Your healthcare provider will decide the dose, route of administration, and duration of the treatment based on your health condition and other factors. Do not self-administer the medicine.

  • Ifosfamide With Mesna

    Description

    This page contains brief details about the drug ifosfamide,mesna, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Ifosfamide, Mesna are alkylating agents and hemorrhagic cystitis inhibitors which was approved for its medical use in the year 1998.

    Mechanism of Action of Ifosfamide With Mesna

    These two combinations together work by damaging the DNA in cancer cells, which leads to cell death and slows the growth and spread of cancer. Mostly, this involves the formation of reactive metabolites in the liver, which are then transported to cancer cells in the body. These metabolites react with the DNA in the cancer cells, causing cross-links and breaks in the DNA strands. This interferes with the replication and transcription of DNA, leading to cell death.

    Uses of Ifosfamide With Mesna

    Ifosfamide, Mesna are indicated for the treatment of bladder inflammation, hemorrhagic cystitis and cancers in the soft tissues, germ cell, pancreas and cervix.

    Ifosfamide With Mesna Dosage available

    It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. Ifosfamide, Mesna is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors. Your doctor will give you certain medications to lessen the chance of getting side effects from the  Ifosfamide, Mesna treatment.

  • Biapenem

    Description

    This page contains brief details about the drug biapenem, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Biapenem contains the active component Biapenem. It is a broad-spectrum antibiotic medication used to treat various bacterial infections. It belongs to the class of antibiotics known as third-generation cephalosporins. This medication works by inhibiting the growth and reproduction of bacteria, helping the immune system eliminate the infection. Biapenem is effective against both gram-positive and gram-negative bacteria.

    Mechanism of Action of Biapenem

    Biapenem exerts a therapeutic effect by inhibiting the growth and spread of bacterial infections. As a broad-spectrum carbapenem antibiotic, it demonstrates potent activity against many Gram-positive and Gram-negative bacteria. By binding to specific bacterial enzymes called penicillin-binding proteins (PBPs), this medication disrupts the synthesis of the bacterial cell wall, leading to cell lysis and death. Its broad coverage makes it effective against various multidrug-resistant bacteria, offering a valuable treatment option in severe or complicated infections.

    Uses of Biapenem

    Biapenem is indicated for complicated intra-abdominal infections, urinary tract infections, and pneumonia. It also treats complicated skin and soft tissue infections, including diabetic foot infections. Its effectiveness against multidrug-resistant bacteria makes it a valuable option in healthcare-associated and nosocomial infections.

    Biapenem Dosage available

    Biapenem is typically administered through injection by a healthcare professional. The dosage and duration of treatment depend on the specific infection being treated, the severity of the infection, and individual patient factors such as age and overall health.

  • Ampicillin, Sulbactam

    Description

    This page contains brief details about the drug ampicillin,sulbactam, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Ampicillin and Sulbactam is a combination antibiotic medication that contains two active ingredients, ampicillin and Sulbactam. It has been used for many years and has well-established safety profiles. They have been extensively studied and are considered safe and effective when prescribed. It is used in the treatment of various bacterial infections. Ampicillin is a penicillin-type antibiotic that works by inhibiting the growth of bacteria. It is effective against both Gram-positive and Gram-negative organisms. Sulbactam is a beta-lactamase inhibitor. Beta-lactamases are enzymes some bacteria produce that can break down certain antibiotics, including penicillins. Combining Sulbactam with ampicillin makes the medication more effective against bacteria that produce beta-lactamases. It received initial FDA approval for use in the United States on October 29, 1986.

    Mechanism of Action of Ampicillin, Sulbactam

    Ampicillin is a penicillin-type antibiotic that belongs to the beta-lactam class. It inhibits the synthesis of bacterial cell walls. Bacterial cell walls are essential for their survival and protection, and without a functional cell wall, bacteria cannot maintain their structure and integrity. Ampicillin interferes with the enzymes involved in synthesizing the bacterial cell wall, leading to its weakening and eventual lysis (breakdown). Sulbactam is a beta-lactamase inhibitor. Beta-lactamase is an enzyme certain bacteria produce to break down and inactivate beta-lactam antibiotics, including penicillins. Combining sulbactam with ampicillin makes the medication effective against bacteria that produce beta-lactamases. Sulbactam inhibits the action of these enzymes, preventing them from degrading ampicillin. This allows ampicillin to remain active and exert its antibacterial effect.

    Uses of Ampicillin, Sulbactam

    The combination of ampicillin and sulbactam is often used to treat various infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and gynecological infections. It is also sometimes used as empiric therapy for suspected mixed infections or when the specific bacteria causing the infection are unknown.

    Ampicillin, Sulbactam Dosage available Ampicillin and Sulbactam is typically administered by a healthcare professional. It is usually given intravenously (IV) as an infusion or injection. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.