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Category: Surgery
Cilastatin+Imipenem
Description
This page contains brief details about the drug cilastatin,imipenem, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved cilastatin + imipenem in 1985. It is used in treating various complex infections in the abdominal region, lung-related infections like pneumonia, and those occurring around the time of childbirth. Additionally, it proves effective against complicated urinary tract infections as well as skin and soft tissue infections. Moreover, this medicine finds utility in managing patients with low white blood cell counts and suspected bacterial-induced fevers. Furthermore, it serves as a viable option for treating bloodstream infections potentially linked to the types of infections.
Mechanism of Action of Cilastatin+Imipenem
Cilastatin acts as a blocker of renal dehydropeptidase-I. Because Imipenem, the antibiotic, is broken down by this enzyme found in the kidney, cilastatin is given alongside imipenem to prevent its breakdown and keep it effective.
Uses of Cilastatin+Imipenem
Cilastatin + imipenem is used to induce muscle relaxation in tracheal tube insertion for artificial ventilation and in intensive care unit surgery (ICU).
Cilastatin+Imipenem Dosage available
This medicine is given only in a hospital setup by a healthcare provider. cilastatin + imipenem will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Factor Vii
Description
This page contains brief details about the drug factor vii, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Factor VII was initially approved by the United States Food and Drug Administration (FDA) on March 25, 1999.
Mechanism of Action of Factor Vii
Factor VII is a blood clotting protein that plays a pivotal role in coagulation. When tissue damage occurs, it interacts with tissue factor (TF) at the injury site, forming the FVIIa-TF complex. This complex acts as an enzyme, triggering a series of reactions that culminate in thrombin formation and the subsequent creation of a blood clot. This mechanism is essential for stopping bleeding after vascular injury.
Uses of Factor Vii
Factor VII is primarily used to treat bleeding disorders. Its key applications include managing bleeding episodes in hemophilia patients with inhibitors, addressing congenital Factor VII deficiency, controlling bleeding during surgery and trauma, managing acquired Factor VII deficiency associated with certain medical conditions, and occasionally, as part of treatment strategies for intracranial hemorrhage.
Factor Vii Dosage available
Factor VII concentrates are typically administered intravenously (IV) to individuals with bleeding disorders. A healthcare provider should determine the specific dosing and administration details based on the patient’s condition and needs.
Human Albumin
Description
This page contains brief details about the drug human albumin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Human Albumin Injection is an albumin solution for injection which was approved by the US Food and Drug Administration for its medical use on 4th August 2014.
Mechanism of Action of Human Albumin
The main mechanism of action of Human Albumin Injection is to increase the colloidal osmotic pressure. It reduces fluid accumulation by pulling the fluid from the intravascular space and increases circulatory blood volume.
Uses of Human Albumin
Human Albumin Injection has been developed to treat hypovolemia, hypoalbuminemia, cardiopulmonary bypass surgery and hemolytic disease of the new born.
Human Albumin Dosage available
Human Albumin is available as 5% and 20% solution for injection. Human Albumin Injection is administered as an intravenous infusion. Your physician will calculate the accurate dose based on your health status and body weight.
Rocuronium Bromide
Description
This page contains brief details about the drug rocuronium bromide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Rocuronium bromide in 1994. Rocuronium bromide is known as muscle relaxants. This medicine is used to induce muscle relaxation during surgeries and in intensive care units (ICU), used in procedures like tracheal tube insertion for artificial ventilation and short-term medical procedures requiring muscle relaxation.
Mechanism of Action of Rocuronium Bromide
Rocuronium bromide acts by blocking the signals between your nerves and muscles, competing with acetylcholine in your body. Acetylcholine normally connects with certain nicotinic cholinergic receptors to make muscles contract. But when this drug is around, it takes the place of acetylcholine, preventing muscle contractions. This happens because it stops the release of calcium ions, which are needed for muscle contraction. Thus, keeping your muscles relaxed.
Uses of Rocuronium Bromide
Rocuronium bromide is used to induce muscle relaxation in tracheal tube insertion for artificial ventilation and in intensive care unit surgery (ICU).
Rocuronium Bromide Dosage available
This medicine is given only in a hospital setup by a healthcare provider. Rocuronium bromide will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Enoxaparin
Description
This page contains brief details about the drug enoxaparin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Enoxaparin is an anticoagulant medication which was approved for its medical use on 31st December 1998.
Mechanism of Action of Enoxaparin
Enoxaparin Injection is an anticoagulant medication belonging to the class of low molecular weight heparin. Enoxaparin injection binds to the antithrombin to form a complex. antithrombin is a protein that blocks the formation of abnormal blood clots. Enoxaparin prevents the activation of factor Xa, eventually preventing clot formation.
Uses of Enoxaparin
Enoxaparin Injection has been developed to treat deep vein thrombosis with or without pulmonary embolism. It also prevents the occurrence of deep vein thrombosis in abdominal surgery, hip replacement surgery, knee replacement surgery and in people with severe movement restriction. In patients with unstable angina and non-Q wave myocardial infarction, Enoxaparin prevents further heart complications.
Enoxaparin Dosage available
A healthcare professional will administer Enoxaparin injection to the patients into their veins. Enoxaparin is available as single dose prefilled syringes in the doses 100 mg per ml and 150 mg per ml. the hundred mg per ml dose is available in the concentrations of 30 MG per 0.3 ml, 40 MG per 0.4 ml, 60mg/0.6ml, 80mg/0.8ml, 100mg/1ml, 300mg/3ml. 150mg/ml dose is available in the concentrations of 120mg/0.8ml and 150mg/1ml.