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Category: Tumors
Lomustine
Description
This page contains brief details about the drug lomustine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved lomustine in 1976. This medicine belongs to a group of monoclonal antibody (a protein made from specific immune cells).
Mechanism of Action of Lomustine
Lomustine works by damaging the DNA and RNA of the cancer cells. This stops their growth and multiplication.
Uses of Lomustine
It is mainly used to treat brain tumors (lumps formed from abnormal cells), lung tumors, Hodgkin’s disease (cancer of lymph system, a part of the immune system), and malignant melanoma (skin cancer).
Lomustine Dosage available
The medicine will be administered to you by a healthcare professional in a hospital setting. It is usually administered in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Plerixafor
Description
This page contains brief details about the drug plerixafor, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA-approved Plerixafor is used to collect blood stem cells. Additionally, it is also used in lymphoma (WBC cancer), multiple myeloma (plasma cell cancer in bone marrow), or solid tumor On 15th December 2008.
Mechanism of Action of Plerixafor
Plerixafor injection works by blocking a protein called CXCR4 (chemokine receptor) on stem cells, which helps them move from the bone marrow into the bloodstream. By blocking CXCR4, Plerixafor causes the stem cells to be released into the bloodstream where the stem cells can be collected and isolated using a machine and stored for transplantation.
Uses of Plerixafor
Plerixafor is used to collect blood stem cells for collection, storage, and transplantation., lymphoma and multiple myeloma in adults, lymphoma or solid tumors in children (aged between 1 to 18).
Plerixafor Dosage available
Plerixafor injection is administered as a subcutaneous injection (under your skin). If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Daunorubicin
Description
This page contains brief details about the drug daunorubicin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Daunorubicin is an anti-cancer drug containing the active constituent daunorubicin. This chemotherapy medication belongs to the anthracycline class of drugs. It is used in the treatment of leukemia. In leukemia, the white blood cells produced in the bone marrow multiply uncontrolled and abnormally. Leukemia is associated with severe infection, extreme tiredness, and joint pain. It is necessary to inform your doctor if you have an infection, cardiac diseases, mouth ulcers, chickenpox or shingles (viral infection), fever, radiation treatment to the chest, kidney stones, and liver disorders.
Daunorubicin was first approved by the FDA in 1979 for the treatment of acute myeloid leukemia (AML). Since then, Daunorubicin has been approved for additional indications and formulations, including for the treatment of solid tumors and lymphomas. Like many chemotherapy drugs, it can cause side effects such as nausea, vomiting, hair loss, fatigue, and an increased risk of infection due to its effect on the immune system.
Mechanism of Action of Daunorubicin
The therapeutic effect of daunorubicin is to inhibit the growth and replication of cancer cells. As a chemotherapy medication, daunorubicin works by binding to DNA and interfering with its replication and transcription, ultimately leading to cell death. Doing so can help shrink tumors, prevent cancer from spreading to other parts of the body, and potentially cure cancer in some cases.
Uses of Daunorubicin
Daunorubicin is primarily used to treat acute myeloid leukemia (AML), a type of cancer that affects the blood and bone marrow. It can also be used to treat other types of cancer, including acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), lymphoma, and solid tumors such as breast and ovarian cancer.
Daunorubicin Dosage available
Daunorubicin is typically administered as an intravenous (IV) infusion or injection in a hospital or clinical setting by a healthcare provider. The exact dosing and frequency of administration will depend on the specific condition being treated and other individual factors, such as the patient’s age, weight, and overall health. If a dose is missed, it’s important to contact your healthcare provider as soon as possible to determine the appropriate course of action. Suppose the missed dose is discovered within a few hours of the scheduled time. In that case, your healthcare provider may recommend administering the missed dose as soon as possible while maintaining the usual interval between doses. However, if more than a few hours have passed since the missed dose, your healthcare provider may recommend skipping the missed dose and resuming the regular dosing schedule at the next scheduled time. It’s important not to double up on doses to make up for a missed one.
Cisplatin
Description
This page contains brief details about the drug cisplatin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Cisplatin as an anticancer medication to treat a certain type of cancer on 19th December 1978.
Mechanism of Action of Cisplatin
Cisplatin belongs to the medication class known as an alkylating agent. It is an anti-cancer medicine that contains the active ingredient Cisplatin. Cisplatin works by stopping the growth and division of cancer cells. It does this by binding to the DNA in the cancer cells and preventing them from replicating.
Uses of Cisplatin
Cisplatin is used to treat testicular tumors, ovarian tumors, bladder tumors, lung cancer, cervical cancer, head and neck epithelial tumors, and. This medicine can prevent the proliferation of cancer cells and prevents cell division which ultimately leads to cell death.
Cisplatin Dosage available Cisplatin injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Octreotide
Description
This page contains brief details about the drug octreotide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Octreotide has been approved to treat acromegaly by the U.S. FDA approved on June 26, 2020.
Mechanism of Action of Octreotide
Somatostatin is a hormone produced by the body on its own. It reduces or stops the production of several hormones, including insulin and gut hormones, and it also regulates the stomach and intestinal emptying.
Octreotide is a somatostatin analog that is made synthetically and slows down hormone production. It helps ease carcinoid syndrome, a type of cancer called carcinoid tumors that release certain chemicals into your bloodstream and slows the spread of the tumor. Flushing of the skin, diarrhea, and stomach pain are a few of the symptoms of carcinoid syndrome you could experience.
Uses of Octreotide
Octreotide treats acromegaly, carcinoid tumors, and vasoactive intestinal peptide tumors (VIPoma).
Octreotide Dosage available
Octreotide is available as an immediate-release solution (liquid) for injection in the doses of 10 mg, 20 mg, and 30 mg. It is intended for administration via the subcutaneous or intravenous route. It must be administered only under the supervision of a healthcare professional at around the same time every day. Check for discoloration and the presence of particles before injecting.