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Category: Uncategorized
Osimertinib
Description
This page contains brief details about the drug osimertinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Osimertinib is an anticancer medication that the Food and Drug Administration approved on the 18th of April 2018 as a first-line treatment for patients having non-small cell lung cancer (NSLC), that has spread to other parts and whose tumors have epidermal growth factor receptor (EGFR) mutations.
Later on the 18th of December 2020, Osimertinib got approval for being used as an additional therapy after tumor removed by surgery in patients having metastatic non-small cell lung cancer (NSLC) whose tumors have epidermal growth factor receptor (EGFR) mutations.
Mechanism of Action of Osimertinib
Osimertinib is a targeted therapy medication and belongs to the category of oral EGFR kinase inhibitor. It works by producing inhibitory action on the Epidermal growth factor receptor (EGFR) and retards the growing cancer cells. Osimertinib also works by slowing down or stopping lung cancer from growing and reducing the tumor size. In addition, it also works by preventing the recurrence of the tumor after its removal through surgery.
Uses of Osimertinib
Osimertinib is indicated to treat non-small cell lung cancer (NSCLS) in adults. It is also used as a first-line treatment for patients having metastatic non-small cell lung cancer (NSLC) whose tumors have epidermal growth factor receptor (EGFR) mutations. In addition, it is also used after the removal of tumors by surgery.
Osimertinib Dosage available
Osimertinib is an prescription medicine available as a tablet in two doses Osimertinib 40mg and Osimertinib 80mg. This medication is to be taken by mouth and swallowed as a whole with or without food at the same time every day as prescribed by your doctor. It should not be crushed, split, or chewed. If you cannot swallow the tablets, you can dissolve them as per your doctor’s advice.
Fludarabine
Description
This page contains brief details about the drug fludarabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Fludarabine is a chemotherapy medication that was approved to be used in 1991.
Mechanism of Action of Fludarabine
Fludarabine works by inhibiting the DNA synthesis in cancer cells, thereby decreasing or stopping them from growing.
Uses of Fludarabine
Fludarabine is a chemotherapy medication that is used in treatment of B-Cell chronic lymphocytic Leukemia (blood cancer).
Fludarabine Dosage available
Fludarabine is given into the vein using an injection and is available in two doses of 10mg and 50 mg.
Vinblastine
Description
This page contains brief details about the drug vinblastine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Vinblastine is an anticancer drug that belongs to the category of medicines known as mitotic inhibitors. It was approved by the U.S. FDA in the year 1962 to treat Hodgkin’s and non-Hodgkin’s lymphoma.
Mechanism of Action of Vinblastine
It works by disrupting the formation of microtubules in cells. Microtubules are structures that help to support and shape cells, as well as transport molecules within cells. In cancer cells, microtubules play a key role in cell division and growth. By interfering with microtubule formation, this drug disrupts the ability of cancer cells to divide and grow, ultimately leading to their death.
Uses of Vinblastine
Vinblastine is used to treat Hodgkin’s and non-Hodgkin’s lymphoma, testicular cancer, breast cancer, and kaposi’s sarcoma.
Vinblastine Dosage available
The medicine will be administered to you by a healthcare professional in a hospital setting. Vinblastine is given as an injection into a vein (intravenous infusion) over a period of 30 minutes, once a day for up to 5 days. The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.
Dacomitinib
Description
This page contains brief details about the drug dacomitinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Dacomitinib is an anticancer agent belonging to the category of kinase inhibitors which was approved for its medical use in 2018.
Mechanism of Action of Dacomitinib
Dacomitinib Tablet is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified under protein tyrosine kinase inhibitors. It has potent activity against EGFR genes (genes that are prominent in non-small cell lung cancer and some types of breast cancer undergoing mutation). On acting against EGFR genes, Dacomitinib interrupts cell signaling and arrests the growth of cancer cells.
Uses of Dacomitinib
Dacomitinib Tablet has been approved to treat non-small cell lung cancer that has spread to other organs.
Dacomitinib Dosage available
Dacomitinib is available as a film-coated tablet in the doses 15mg, 30mg and 45mg. The recommended dose is 45mg once a day with or without food. It is advisable to swallow the whole tablet and take them at the same time each day. Your healthcare provider may alter the dose depending on how well your body tolerates it.
Imatinib Mesylate (Alpha 2-Form)
Oncology
Erlotinib Hydrochloride
Oncology