Gemcitabine

Description

This page contains brief details about the drug gemcitabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The U.S. FDA approved Gemcitabine as a chemotherapeutic anticancer medication to treat bladder, breast, ovarian, pancreatic, and non-small cell lung cancers on 10th January 1995.

Mechanism of Action of Gemcitabine

Gemcitabine is a cytotoxic agent belonging to the category of medications called antimetabolites. It inhibits DNA polymerase enzyme, breaks the DNA strands, interferes with cell signalling and eventually prevents the multiplication of cancer cells. Gemcitabine is prescribed alone and also in combination with other anticancer medications like Cisplatin and Carboplatin.

Uses of Gemcitabine

Gemcitabine has been developed to treat ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer in patients who have failed to respond to previous therapies.

Gemcitabine Dosage available

Gemcitabine is available for administration as an intravenous infusion that is injected through the veins of patients with ovarian, breast, and non-small cell lung cancer. Your physician will choose the dosage and administration frequency based on your medical condition and type of cancer because it differs for each person.