Nintedanib

Description

This page contains brief details about the drug nintedanib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The U.S. FDA-approved Nintedanib treated people with a lung disease such as idiopathic pulmonary fibrosis (IPF), a chronic fibrosing lung disease with a progressive phenotype, systemic sclerosis, on  15th Sept 2014.

Mechanism of Action of Nintedanib

Nintedanib works by inhibiting receptor multiple tyrosine kinases (RTKs) enzyme that develops and progresses lung fibrosis (scarring). Inhibiting these enzymes reduces the development of fibrous tissue in the lungs.

Uses of Nintedanib

Nintedanib is used to treat idiopathic pulmonary fibrosis (IPF), a chronic fibrosing lung disease with a progressive phenotype, systemic sclerosis. This interferes with the production and migration of fibroblasts responsible for lung scars and affects its signaling. This helps to reduce further scarring and stiffening of the lungs.

Nintedanib Dosage available

Take Nintedanib as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration based on your age, body weight, and disease condition. Do not stop taking Nintedanib unless your doctor advises you to stop.