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Enzalutamide
Description
This page contains brief details about the drug enzalutamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Enzalutamide is an anticancer drug that belongs to the category of medicines known as antimetabolite. It was approved by the U.S. FDA on 31st of August 2012 to treat Prostate cancer.
Mechanism of Action of Enzalutamide
It works by inhibiting the active form of testosterone, called dihydrotestosterone. It selectively blocks the androgen receptors and disrupts the translocation of signals from the receptor to the cell. Thus, the androgen hormone does not bind to the androgen receptors and these androgen receptors do not interact with DNA. This blocks the functioning of cancer cells and reduces its multiplication.
Uses of Enzalutamide
Enzalutamide is prescribed to treat metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC).
Enzalutamide Dosage available
Enzalutamide is to be administered orally. This medication is to be swallowed as whole with water, without cutting, crushing or chewing. It can be taken with or without food.
Daptomycin
Description
This page contains brief details about the drug daptomycin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Daptomycin received its initial approval from the U.S. Food and Drug Administration (FDA) on September 1, 2003. It was first approved under the brand name Cubicin
Mechanism of Action of Daptomycin
Daptomycin’s mechanism of action involves disrupting the bacterial cell membrane. It binds to the bacterial cell surface, leading to rapid depolarization of the cell membrane, resulting in the leakage of cellular contents and ultimately causing bacterial cell death. By targeting the cell membrane, this medication is effective against many gram-positive bacteria, including MRSA and VRE, and is less likely to promote rapid resistance development.
Uses of Daptomycin
Daptomycin treats complicated skin and skin structure infections (cSSSI) and bloodstream infections caused by certain gram-positive bacteria, including vancomycin-resistant enterococcus (MRSA) and methicillin-resistant staphylococcus VRE.
Daptomycin Dosage available
Daptomycin is administered intravenously (IV) by a healthcare professional. The lyophilized powder is reconstituted with sterile water to prepare the solution for IV infusion. The recommended dosage and infusion rate vary based on the type and severity of the infection, as well as the patient’s weight and kidney function. This medication is usually given once daily.
Cytarabine
Description
This page contains brief details about the drug cytarabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Cytarabine is an antineoplastic agent that belongs to the class antimetabolite. Initially, FDA approved it on January 01, 1999, for its medical use.
Mechanism of Action of Cytarabine
Cytarabine is a cytotoxic drug that acts by primarily killing cells undergoing DNA synthesis. It works by slowing or stopping the growth of cancer cells in your body.
Uses of Cytarabine
Cytarabine is a prescription drug and it is used alone or with other chemotherapy medications to treat certain types of leukemias (a type of blood cancer with too many white blood cells), including acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML). It is also indicated to use alone or with other chemotherapy drugs to treat and prevent meningeal leukemia (cancer in the membrane that covers and protects the spinal cord and brain).
Cytarabine Dosage available
A trained healthcare professional will give you Cytarabine in a hospital setting. It is available as an injection for solution. This medicine may be given by solution for injection/infusion (using a syringe) under the skin (subcutaneous) or into a vein (intravenously) or into a muscle (intramuscularly), or into the spine (intrathecal). Your doctor will decide the dose, route of administration, and duration of the treatment based on your disease condition, severity, and other factors.
Cyclosporine
Description
This page contains brief details about the drug cyclosporine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Cyclosporine is an immunosuppressant which was approved for its medical use on 1983.
Mechanism of Action of Cyclosporine
Cyclosporine is an immunosuppressant which prevents organ rejection in organ transplantation. It is classified as an immunosuppressant belonging to the category of Calcineurin inhibitors. Cyclosporine works inhibiting cytochrome P450 3A4, P-glycoprotein and interleukins to suppress the cell mediated immune response. Cyclosporine is often prescribed along with other immunosuppressants like azathioprine and mycophenolate mofetil.
Uses of Cyclosporine
Cyclosporine has been developed to prevent organ rejection in adult and pediatric patients receiving an allogeneic transplant of the liver, kidney, heart, or lung. it is indicated for It is also prescribed to treat rheumatoid arthritis for patients who have not responded adequately to methotrexate.
Cyclosporine Dosage available
Cyclosporine is available in the form of capsule, injection and oral solution. Cyclosporine Capsule is available in the doses 25mg, 50mg and 100mg. Your healthcare provider will administer Cyclosporine 50mg Injection if you are unable to tolerate oral capsule or suspension. Your healthcare provider will prescribe the accurate dose based on the organ transplanted, body weight and health condition.
Caspofungin Acetate
Description
This page contains brief details about the drug caspofungin acetate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Caspofungin Acetate for fungal infections on December 30, 2004. This belongs to the medication class known as an antifungal.
Mechanism of Action of Caspofungin Acetate
Caspofungin Acetate works by weakening fungal cells and inhibiting their growth, preventing the spread of infection. This allows the body’s natural defenses to effectively eliminate the infection.
Uses of Caspofungin Acetate
Caspofungin Acetate is used in the treatment of candidemia, esophageal candidiasis, other Candida infections, and aspergillosis, which is a fungal infection in the lungs.
Caspofungin Acetate Dosage available
Caspofungin Acetate will be administered to you by a healthcare professional in a hospital setting. It is usually administered in a vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Aprepitant
Description
This page contains brief details about the drug aprepitant, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA-approved Aprepitant to prevent nausea and vomiting due to chemotherapy on 26th March 2003.
Mechanism of Action of Aprepitant
Aprepitant capsule blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.
Uses of Aprepitant
Aprepitant is used to prevent nausea and vomiting due to chemotherapy in adults and children of twelve years and older.
Aprepitant Dosage available
Swallow the Aprepitant capsule as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the dosage based on your medical condition because it differs for each person. Only stop taking Aprepitant if your doctor advises you to stop.
Apixaban
Description
This page contains brief details about the drug apixaban, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Apixaban is an anticoagulant drug that belongs to the category of medicines known as Factor Xa Inhibitors. It was approved on 28 December 2012 to prevent blood clots.
Mechanism of Action of Apixaban
It is a direct factor Xa inhibitor, which works majorly through the process of alkylation. It enters the cancer cells after getting activated by the liver and inhibits DNA synthesis. This process disrupts the normal cell cycle and DNA function, leading to arrest in cancer cell growth and multiplication.
Uses of Apixaban
Apixaban has been developed as a direct oral anticoagulant (DOACs) drug to prevent strokes and blood clots in people with atrial fibrillation, deep vein thrombosis, or pulmonary embolism.
Apixaban Dosage available
Your doctor will decide the dose and duration of Apixaban based on the disease condition. Always take this medicine as prescribed by your doctor. The recommended starting oral dose of axitinib is 2.5 mg twice daily. Take the tablet at the same time everyday, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
Apalutamide
Description
This page contains brief details about the drug apalutamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Apalutamide is an anticancer drug in the androgen receptor inhibitors class of medications. The FDA approved the medicine for its medical use on September 17, 2019.
Mechanism of Action of Apalutamide
Apalutamide is a selective androgen receptor (AR) inhibitor that binds directly to the androgen receptor binding domain. It inhibits protein transportation in the nucleus, DNA binding, and AR-mediated transcription. Treatment with Apalutamide reduces cancer cell growth and increases cell death, resulting in effective anticancer activity.
Uses of Apalutamide
It is indicated for treating patients with certain types of prostate cancer whose cancer has spread to other parts of the body and still responds to a medical or surgical treatment that lowers testosterone (male reproductive hormone) or whose cancer has not spread to other parts of the body and no longer responds to a medical or surgical treatment that lowers testosterone.
Apalutamide Dosage available
Apalutamide is an orally administered drug. Take medicine as informed by your physician. It is generally taken with or without food once a day. Take the tablet at around the same time every day. Swallow the tablets whole; do not split, chew, or crush them. Do not stop taking Apalutamide without talking to your doctor.
Atazanavir,Ritonavir
Description
This page contains brief details about the drug atazanavir,ritonavir, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Atazanavir, Ritonavir is an antiviral medication developed by the U.S. Food And Drug Administration for treating HIV-1 infection.
Mechanism of Action of Atazanavir,Ritonavir
Atazanavir, Ritonavir is indicated to treat HIV-1 infection. It is a Human immunodeficiency virus that mainly occurs when a person’s immune system is attacked and weakened by the human immunodeficiency virus (HIV). This infection progressively weakens the immune system, making individuals more susceptible to opportunistic infections.
Uses of Atazanavir,Ritonavir
Atazanavir, Ritonavir work together to inhibit the protease enzyme, which is necessary for the replication of HIV. By blocking this enzyme, this drug prevents the virus from multiplying and spreading in the body. It mainly helps reduce the viral load and slow the progression of HIV infection.
Atazanavir,Ritonavir Dosage available
It is an orally available prescription drug. Your doctor will decide the dose and duration of Atazanavir, Ritonavir based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, or crush the tablet. Swallow the whole tablet with water.
Anidulafungin
Description
This page contains brief details about the drug anidulafungin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Anidulafungin is an antifungal medication developed by the U.S. Food And Drug Administration and initially approved on 21 Feb 2006 for treating serious fungal infections.
Mechanism of Action of Anidulafungin
Anidulafungin works by inhibiting the beta-glucan synthesis in the cell walls of susceptible fungi. This disruption weakens the fungal cell wall, leading to the death of the fungus.
Uses of Anidulafungin
Anidulafungin helps to treat certain invasive fungal infections. It is effective against various types of invasive candidiasis, such as candidemia (Candida bloodstream infection) and esophageal candidiasis (fungal infection affecting the esophagus). Invasive candidiasis occurs when candida yeasts enter the bloodstream or other internal organs and cause systemic infections.
Anidulafungin Dosage available
Anidulafungin is administered directly into the vein intravenously (IV). It is available as a powder for reconstitution, and a physician will prepare and administer the medication through a vein. The IV infusion is usually given over a period of one to two hours.