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Nilotinib
Description
This page contains brief details about the drug nilotinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA-approved Aprepitant for the treatment of chronic myeloid leukemia (CML) on October 29, 2007.
Mechanism of Action of Nilotinib
BCR-ABL tyrosine kinase is responsible for the uncontrolled division of cells in the CML. Nilotinib disrupts the signaling route of the protein kinase enzyme which targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.
Uses of Nilotinib
This medicine is used to treat a type of leukemia called Philadelphia chromosome-positive chronic myeloid leukemia (Ph-positive CML), a blood cancer with abnormal production of WBC. In adult and pediatric patients, it is used in a patient who is newly diagnosed with Chronic Myeloid Leukemia (CML) and those facing side effects from previous treatment. Additionally, it is also used in patients with no longer respond to the previous treatment including Imatinib.
Nilotinib Dosage available
Take Nilotinib as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking Nilotinib unless your doctor advises you to stop.
Teicoplanin
Description
This page contains brief details about the drug teicoplanin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Teicoplanin is an antibiotic that belongs to the class of medications called semisynthetic glycopeptide. The FDA approved this medicine for its use on 24 May 2018. FDA did not approve it for use in the USA.
Mechanism of Action of Teicoplanin
The cell wall of gram-positive bacteria is entirely made of peptidoglycan, which is necessary for cell wall synthesis. Teicoplanin interferes with the cell-wall biosynthesis of bacteria by binding to specific residues and inhibiting the polymer membrane. It works by killing the bacteria which can cause serious infections.
Uses of Teicoplanin
It is used in adults and children to treat bacterial infections of soft tissues, lungs, urinary tract, endocarditis, abdominal wall, blood, bones, and joints. It works by killing the bacteria that cause infections in the body.
Teicoplanin Dosage available
Teicoplanin is available as an injection. It will be given to you by a doctor or other healthcare professional. It will be given as an intravenous injection (into a vein) or intramuscular (into a muscle). It can also be given as an infusion through a drip into a vein. Your healthcare provider will decide the dose, route of administration, and duration of the treatment based on your health condition and other factors. Do not self-administer the medicine.
Osimertinib
Description
This page contains brief details about the drug osimertinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Osimertinib is an anticancer medication that the Food and Drug Administration approved on the 18th of April 2018 as a first-line treatment for patients having non-small cell lung cancer (NSLC), that has spread to other parts and whose tumors have epidermal growth factor receptor (EGFR) mutations.
Later on the 18th of December 2020, Osimertinib got approval for being used as an additional therapy after tumor removed by surgery in patients having metastatic non-small cell lung cancer (NSLC) whose tumors have epidermal growth factor receptor (EGFR) mutations.
Mechanism of Action of Osimertinib
Osimertinib is a targeted therapy medication and belongs to the category of oral EGFR kinase inhibitor. It works by producing inhibitory action on the Epidermal growth factor receptor (EGFR) and retards the growing cancer cells. Osimertinib also works by slowing down or stopping lung cancer from growing and reducing the tumor size. In addition, it also works by preventing the recurrence of the tumor after its removal through surgery.
Uses of Osimertinib
Osimertinib is indicated to treat non-small cell lung cancer (NSCLS) in adults. It is also used as a first-line treatment for patients having metastatic non-small cell lung cancer (NSLC) whose tumors have epidermal growth factor receptor (EGFR) mutations. In addition, it is also used after the removal of tumors by surgery.
Osimertinib Dosage available
Osimertinib is an prescription medicine available as a tablet in two doses Osimertinib 40mg and Osimertinib 80mg. This medication is to be taken by mouth and swallowed as a whole with or without food at the same time every day as prescribed by your doctor. It should not be crushed, split, or chewed. If you cannot swallow the tablets, you can dissolve them as per your doctor’s advice.
Emtricitabine+Tenofovir Alafenamide
Description
This page contains brief details about the drug emtricitabine,tenofovir alafenamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Emtricitabine + Tenofovir alafenamide is a combination of anti-retroviral drug. Emtricitabine belongs to the class of medication called nucleoside reverse transcriptase inhibitor (NRTI), and Tenofovir alafenamide belongs to the class called nucleotide reverse transcriptase inhibitor (NtRTI). FDA approved it initially in September 2015 for its medical use.
Mechanism of Action of Emtricitabine+Tenofovir Alafenamide
Emtricitabine and Tenofovir alafenamide are nucleoside/nucleotide analog reverse transcriptase inhibitors, exhibiting their antiviral effect by competing with natural substrates and incorporating them into viral DNA, resulting in the termination of the DNA chain.
Uses of Emtricitabine+Tenofovir Alafenamide
Emtricitabine+Tenofovir alafenamide is used in combination with other medicines to treat human immunodeficiency virus (HIV-1) infection in adults and adolescents 12 years of age and who weigh at least 35kg. They work by slowing the spread of HIV in the body.
Emtricitabine+Tenofovir Alafenamide Dosage available
It is an orally available prescription drug. Your doctor will decide the dose and duration of Emtricitabine+Tenofovir alafenamide based on the disease condition and other factors such as body weight and age. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with a glass of water. If you have difficulty swallowing the tablet, you can split it in half after consulting with your doctor.
Hyaluronic Acid
Description
This page contains brief details about the drug hyaluronic acid, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Hyaluronic acid is a high molecular weight polysaccharide approved for its medical use in 1997.
Mechanism of Action of Hyaluronic Acid
Hyaluronic acid is a biological agent that is naturally present in the synovial fluid and cartilage of the joints. Hyaluronic Acid decreases in concentration when a person has joint disorders like osteoarthritis, which leads to the low viscosity of the synovial fluid. Hyaluronic Acid Injection restores the viscosity of the joint fluid (synovial fluid), reduces friction, and alleviates pain.
Uses of Hyaluronic Acid
Hyaluronic acid Injection has been developed to treat symptoms of pain in patients diagnosed with osteoarthritis of the knees who have not responded to conventional treatment methods like painkillers, exercise, and physical therapy. This injection improves mobility and enhances joint function.
Hyaluronic Acid Dosage available
A healthcare professional will administer Hyaluronic acid as an intraarticular injection to the patients. The dose will depend on the patient’s severity of the condition. Hyaluronic Acid is available as a prefilled syringe in the doses 20mg and 60mg. Your healthcare provider will inject this medicine directly into the affected joint.
Ceritinib
Description
This page contains brief details about the drug ceritinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Ceritinib is a targeted cancer therapy drug belonging to the class of tyrosine kinase inhibitors. It was approved for its medical use on 29th April 2014.
Mechanism of Action of Ceritinib
Ceritinib Capsule is indicated to treat the advanced stage of lung cancer as an initial treatment and is also recommended when anticancer treatment with Crizotinib did not work. It is prescribed to treat non-small cell lung cancer caused by defects in the ALK-positive genes.
Uses of Ceritinib
Ceritinib Capsule is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a tyrosine kinase inhibitor. Anaplastic lymphoma kinase is a significant gene that result in non-small cell lung cancer by undergoing mutation. Ceritinib inhibits ALK genes and stops the growth and development of cancer cells by shrinking them.
Ceritinib Dosage available
Ceritinib is available in the form of hard gelatin capsules in a dose of 150mg. The recommended dose is three 150mg capsules once daily. It is advisable to take this medicine simultaneously each day with or without food. Swallow the capsule and do not crush, open, or dissolve them.
Oseltamivir Phosphate
Description
This page contains brief details about the drug oseltamivir phosphate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Oseltamivir Phosphate is an anti-viral medication that belongs to neuraminidase inhibitor and was approved by the FDA on December 14, 2000, for the treatment and prevention of influenza A and B.
Mechanism of Action of Oseltamivir Phosphate
Oseltamivir Phosphate is a pro-drug that gets converted into its active form (Oseltamivir carboxylate) inside the body. It is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza. It works by inhibiting the neuraminidase enzyme present on the surface of the virus. This enzyme is essential for the virus to enter the healthy cells and release newly formed virus particles from infected cells, thereby spreading the infectious virus throughout the body. Oseltamivir Phosphate reduces viral shedding and infectivity.
Uses of Oseltamivir Phosphate
Oseltamivir Phosphate is used to treat Influenza A and B in patients two weeks of age and older who do not have symptoms for more than 2 days. It also prevents influenza type A and B in patients 1 year and older.
Oseltamivir Phosphate Dosage available
Oseltamivir Phosphate is a prescription drug available as an oral capsule and suspension. The dosage form, dose, and frequency of administration will be decided by your doctor based on your disease condition and other factors. Take medicine as directed by your physician. Take it with or without food. The chances of stomach upset are less if you take this medicine with food. If you are prescribed a capsule, swallow the capsule as a whole with water. Do not break, chew or crush the capsule.
Oral suspension is prescribed when the patient cannot swallow the tablet form of this medicine. Shake the suspension well before every use. The recommended dose is based on the individual’s body weight. It is important to complete the whole course, even if you start to feel better quickly.
Secukinumab
Description
This page contains brief details about the drug secukinumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Secukinumab is a monoclonal antibody (protein which attaches to a specific target) which was approved for its medical use on 10th November 2014.
Mechanism of Action of Secukinumab
Secukinumab Injection is a biological agent that belongs to the group of human IgG1 monoclonal antibody. Secukinumab specifically targets and binds to the interleukin 17A cytokine. Interleukin 17A is an inflammatory mediator that is present in high concentrations in inflammatory diseases. Secukinumab blocks the interaction of this protein with its receptors and eventually lower the inflammatory effects.
Uses of Secukinumab
Secukinumab Injection has been developed to treat various inflammatory conditions like plaque psoriasis, psoriatic arthritis, radiographic and non-radiographic axial spondyloarthritis and ankylosing spondylosis.
Secukinumab Dosage available
Secukinumab is available as a powder for solution for injection in the dose 150mg, intended for subcutaneous administration. For adults with plaque psoriasis and psoriatic arthritis, the recommended dose is 300mg subcutaneous injection once a week for 4 weeks. For paediatric patients and adults with axial spondyloarthritis, the recommended dose is 150mg once a week for 4 weeks.
Semaglutide
Description
This page contains brief details about the drug semaglutide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Semaglutide was initially approved by the U.S. Food and Drug Administration (FDA) on December 5, 2017, for treating type 2 diabetes. Since then, it has also received additional approvals for its use in chronic weight management.
Mechanism of Action of Semaglutide
Semaglutide, a GLP-1 receptor agonist, exerts its therapeutic effects by mimicking the action of the naturally occurring hormone GLP-1. In diabetes management, this medication enhances insulin secretion, inhibits glucagon release, slows gastric emptying, and decreases hepatic glucose production. This medication effect leads to improved glycemic control and reduced HbA1c levels. Additionally, this medication promotes weight loss through increased satiety, decreased food intake, and modulation of gastric function. It has also demonstrated cardiovascular benefits, including potentially reducing major cardiovascular events.
Uses of Semaglutide
rSemaglutide is used to improve blood sugar control in type 2 diabetes and aid in weight management in individuals with obesity or overweight.
Semaglutide Dosage available
Semaglutide is typically administered as a subcutaneous injection at a convenient time once a week, on the same day each week. The injection can be given in the abdomen, thigh, or upper arm. These medication pens come with clear instructions on how to load the needle, dial the dose, and administer the injection. After injecting, dispose of the needle safely in a sharps container. Regular monitoring and follow-up with your healthcare provider are important to assess your progress and make any necessary adjustments to your treatment plan.
Romiplostim
Description
This page contains brief details about the drug romiplostim, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Romiplostim is a thrombopoietin receptor agonist which was approved for its medical use on 22nd August 2008.
Mechanism of Action of Romiplostim
Romiplostim Injection is medication belonging to the category of thrombopoietin receptor agonists. It activates human thrombopoietin receptors and induces the cells in the bone marrow to produce more platelets and arrests bleeding.
Uses of Romiplostim
Romiplostim Injection has been developed for adults and paediatric patients older than 1 year of age with immune thrombocytopenia, who have inadequately responded to corticosteroids, immunoglobulins and splenectomy.
Romiplostim Dosage available
A healthcare professional will administer Romiplostim injection to the patients through subcutaneous route. Romiplostim is available as single-dose lyophilized powder for injection in the doses 125mcg, 250mcg and 500mcg. The initial recommended dose is 1mcg/kg body weight once a week. The dose will be further adjusted according to the platelet response.