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Ampicillin, Sulbactam
Description
This page contains brief details about the drug ampicillin,sulbactam, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Ampicillin and Sulbactam is a combination antibiotic medication that contains two active ingredients, ampicillin and Sulbactam. It has been used for many years and has well-established safety profiles. They have been extensively studied and are considered safe and effective when prescribed. It is used in the treatment of various bacterial infections. Ampicillin is a penicillin-type antibiotic that works by inhibiting the growth of bacteria. It is effective against both Gram-positive and Gram-negative organisms. Sulbactam is a beta-lactamase inhibitor. Beta-lactamases are enzymes some bacteria produce that can break down certain antibiotics, including penicillins. Combining Sulbactam with ampicillin makes the medication more effective against bacteria that produce beta-lactamases. It received initial FDA approval for use in the United States on October 29, 1986.
Mechanism of Action of Ampicillin, Sulbactam
Ampicillin is a penicillin-type antibiotic that belongs to the beta-lactam class. It inhibits the synthesis of bacterial cell walls. Bacterial cell walls are essential for their survival and protection, and without a functional cell wall, bacteria cannot maintain their structure and integrity. Ampicillin interferes with the enzymes involved in synthesizing the bacterial cell wall, leading to its weakening and eventual lysis (breakdown). Sulbactam is a beta-lactamase inhibitor. Beta-lactamase is an enzyme certain bacteria produce to break down and inactivate beta-lactam antibiotics, including penicillins. Combining sulbactam with ampicillin makes the medication effective against bacteria that produce beta-lactamases. Sulbactam inhibits the action of these enzymes, preventing them from degrading ampicillin. This allows ampicillin to remain active and exert its antibacterial effect.
Uses of Ampicillin, Sulbactam
The combination of ampicillin and sulbactam is often used to treat various infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and gynecological infections. It is also sometimes used as empiric therapy for suspected mixed infections or when the specific bacteria causing the infection are unknown.
Ampicillin, Sulbactam Dosage available Ampicillin and Sulbactam is typically administered by a healthcare professional. It is usually given intravenously (IV) as an infusion or injection. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.
Ranibizumab
Description
This page contains brief details about the drug ranibizumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Ranibizumab is an anti-neovascularisation agent in the class of medications called vascular endothelial growth factor A (VEGF-A) antagonists. Initially, FDA approved this medicine on 30th June 2006 for its medical use.
Mechanism of Action of Ranibizumab
Ranibizumab specifically recognizes and binds to a protein called human vascular endothelial growth factor A (VEGF-A) present in the eye. In excess, VEGF-A causes abnormal blood vessel growth and swelling in the eye, leading to impairment of vision in certain eye diseases. This medicine can block its actions and prevent this abnormal growth and swelling. This injection can help to stabilize and improve your vision.
Uses of Ranibizumab
It is used in adults to treat several eye diseases causing vision impairment. It is used to treat wet age-related macular degeneration (AMD, a persistent eye disease that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities).
Ranibizumab is also used to treat myopic choroidal neovascularization (mCNV; a complication in near-sighted people where new blood vessels can grow in the back of the eye), and to treat macular edema after retinal vein occlusion (an eye disease caused by blockage of blood flow from the eye that leads to blurry vision and vision loss). It is also used to treat diabetic macular edema (an eye disease caused by diabetes that can lead to vision loss) and diabetic retinopathy (damage to the eyes caused by diabetes).
Ranibizumab Dosage available Ranibizumab is administered as an injection into your eye by an eye doctor under a local anesthetic. Your doctor will decide the dose and frequency of the injection based on your disease condition. Do not self-administer the medicine.
Cefoperazone, Sulbactam
Description
This page contains brief details about the drug cefoperazone,sulbactam, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Cefoperazone + Sulbactam is an antibiotic medication developed by the U.S. Food And Drug Administration and initially approved in the year 1981, for treating serious infections such as urinary tract infections, respiratory tract infections, intra-abdominal infections, septicemia, meningitis, skin infections, bone infections, and endometritis.
Mechanism of Action of Cefoperazone, Sulbactam
Cefoperazone is an antibiotic that works by interfering with bacterial cell wall synthesis, leading to the destruction of the bacteria. Sulbactam, the beta-lactamase inhibitor, helps inactivate the beta-lactamase enzymes produced by certain bacteria. This prevents the breakdown of cefoperazone by these enzymes, enhancing its effectiveness against resistant bacteria.
Uses of Cefoperazone, Sulbactam
Cefoperazone + Sulbactam this combination is effective against a wide range of bacteria and this drug is commonly used to treat serious infections such as urinary tract infections, respiratory tract infections, intra-abdominal infections, septicemia, meningitis, skin infections, bone infections, and endometritis.
Cefoperazone, Sulbactam Dosage available This injection is available with a dose of 2gm, 3gm and 1.5gm. Do not self-administer the Cefoperazone + Sulbactam injection. Your doctor will decide the duration and dose of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for unwanted side effects.
Zoledronic Acid
Description
This page contains brief details about the drug zoledronic acid, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Zoledronic Acid is an anti-resorptive medication which was approved for its medical use on 22nd February 2002.
Mechanism of Action of Zoledronic Acid
Zoledronic Acid Injection is an anti-resorptive medication that belongs to the class of bisphosphonates. Zoledronic acid works by inhibiting the cell signaling pathways that produce osteoclasts. This process further inhibits bone resorption and also induces programmed cell death of cancer cells.
Uses of Zoledronic Acid
Zoledronic Acid Injection has been developed to treat osteoporosis and prevent bone complications in patients diagnosed with bone cancer. A condition called tumor-induced hypercalcemia is common among people diagnosed with cancer. Zoledronic acid Injection is indicated to reduce blood calcium levels in such conditions.
Zoledronic Acid Dosage available Zoledronic Acid Injection is available as a single-dose vial for injection in doses 4mg and 5mg. It is intended for administration as an intravenous infusion after reconstitution. Your healthcare provider will prescribe an accurate dose depending on your health condition. If you have been diagnosed with a kidney problem, your doctor will administer a lower dose.
Abiraterone Acetate
Description
This page contains brief details about the drug abiraterone acetate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
On April 28, 2011, the U.S. FDA approved Abiraterone acetate to be used in Combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer who have received prior chemotherapy containing docetaxel.
Mechanism of Action of Abiraterone Acetate
Prostate cancer occurs due to excessive production of male hormones (androgens/ testosterone). Androgens are produced by the testicles, adrenal glands and metastatic tumor. Abiraterone acetate works by interfering and inhibiting the enzyme CYP17A1 that acts as a catalyst in the production of the androgens. Inhibition of this enzyme, reduces the amount of androgens produced in the body.
Uses of Abiraterone Acetate
Abiraterone acetate is used in treatment of prostate cancer.
Abiraterone Acetate Dosage available
This medication is to be taken as prescribed by your doctor. Abiraterone acetate is administered orally (by mouth) and the recommended dose is 1000mg (two tablets) once a day. This medication is not to be taken with food and must be consumed whole without breaking it.
Bevacizumab
This page contains brief details about the drug bevacizumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Bevacizumab is the first antiangiogenic agent (a drug that blocks the formation of blood vessels) which was approved for its medical use in 2004.
Mechanism of Action of Bevacizumab
Bevacizumab Injection is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a monoclonal antibody belonging to the class VEGF inhibitors. VEGF -A is a factor involved in the formation of blood vessels within the tumor that feed the tumors with adequate nutrition and oxygen for the tumor growth. Thus, bevacizumab selectively binds to the tumor and prevents its growth. It is often administered in combination with other chemotherapy agents.
Uses of Bevacizumab
Bevacizumab Injection has been developed to treat solid tumors by injecting it directly into the bloodstream. Bevacizumab Injection has been approved to treat several primary and advanced-stage cancers such as metastatic breast cancer, metastatic cervical cancer, Glioblastoma multiforme (brain cancer), advanced kidney cancer, metastatic colorectal cancer, advanced non-small-cell lung cancer, Liver Cancer- Hepatocellular carcinoma and the cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer.
Bevacizumab Dosage available
A healthcare professional will administer Bevacizumab injection as an intravenous infusion to the patients. The first dose will be given for 90 minutes and later the duration of the infusion will be reduced to 30 minutes if the patient is well tolerated. The number of infusions to be administered is typically based on the patient’s response to the therapy.
The oncologist will calculate the amount of Bevacizumab Injection administered based on the patients’ height, weight, body surface area, and the type of cancer being diagnosed. This injection is available in two dosages i.e bevacizumab 100mg injection and 400mg injection. Each 4ml vial contains 100mg of Bevacizumab Injection and a 16ml vial contains 400mg of Bevacizumab Injection.
Mercaptopurine
Description
This page contains brief details about the drug mercaptopurine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Mercaptopurine is an anticancer drug that belongs to the class of medicines known as purine antagonists. It was approved by the U.S. FDA on 28th of April 2014 to treat acute lymphoblastic leukaemia.
Mechanism of Action of Mercaptopurine
It works by interfering with the DNA and RNA function in cancer cells, inhibiting nucleotide synthesis, suppressing the immune system, and activating enzymes that can kill cancer cells. It is usually used in combination with other chemotherapy drugs to increase its effectiveness.
Uses of Mercaptopurine
Mercaptopurine is used in the treatment of acute lymphoblastic leukaemia.
Mercaptopurine Dosage available Mercaptopurine is to be administered orally. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose. You must take these tablets at least 1 hour before or 2 hours after having milk or dairy products.
Fluorouracil
Description
This page contains brief details about the drug fluorouracil, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Fluorouracil contains the active ingredient Fluorouracil. It belongs to a class of drugs called antimetabolites, which interfere with the genetic material (DNA and RNA) synthesis of rapidly dividing cancer cells, leading to their death. This medication is commonly used to treat breast, colorectal, stomach, esophagus, and pancreatic cancers. It can be administered in different ways, including through injection or as a cream.
Fluorouracil (5-fluorouracil or 5-FU) was first approved by the US Food and Drug Administration (FDA) in 1959 for treating colon and rectal cancer. Since then, it has been approved for treating other types of cancer, including breast, stomach, and pancreatic cancer. The drug is also approved in many other countries around the world. Over the years, many studies proved the effectiveness of fluorouracil in combination with other cancer treatments, and the drug continues to be an important chemotherapy medication for cancer patients.
Mechanism of Action of Fluorouracil
Fluorouracil work by interfering with the DNA and RNA synthesis of rapidly dividing cancer cells, leading to their death. It is an antimetabolite chemotherapy drug that mimics the structure of normal DNA and RNA building blocks. Still, its incorporation into DNA and RNA leads to errors in formation and causes damage to the DNA and RNA strands.
Uses of Fluorouracil
Fluorouracil is a chemotherapy medication commonly used to treat different types of cancer, including breast, colon, rectal, stomach, and pancreatic cancers. It works by interfering with the growth and division of cancer cells, ultimately causing them to die.
Fluorouracil Dosage available
Fluorouracil is a medication typically administered under a healthcare provider’s supervision, usually in a hospital or clinic setting. The method of administration can vary depending on the type of cancer and the individual patient’s condition. The injection can be given in a vein (intravenous) or muscle (intramuscular) injection. If a patient misses a scheduled dose, they should contact their healthcare provider immediately to determine the next steps. Sometimes, the missed dose may be rescheduled, or a new treatment plan may be recommended. It is important to follow the healthcare provider’s instructions closely and not make any changes to the treatment plan without first consulting with them. Patients should never take a double dose to make up for a missed dose, as this can increase the risk of side effects and toxicity.
5FU GLS
Description
This page contains brief details about the drug fluorouracil, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Fluorouracil contains the active ingredient Fluorouracil. It belongs to a class of drugs called antimetabolites, which interfere with the genetic material (DNA and RNA) synthesis of rapidly dividing cancer cells, leading to their death. This medication is commonly used to treat breast, colorectal, stomach, esophagus, and pancreatic cancers. It can be administered in different ways, including through injection or as a cream.
Fluorouracil (5-fluorouracil or 5-FU) was first approved by the US Food and Drug Administration (FDA) in 1959 for treating colon and rectal cancer. Since then, it has been approved for treating other types of cancer, including breast, stomach, and pancreatic cancer. The drug is also approved in many other countries around the world. Over the years, many studies proved the effectiveness of fluorouracil in combination with other cancer treatments, and the drug continues to be an important chemotherapy medication for cancer patients.
Mechanism of Action of Fluorouracil
Fluorouracil work by interfering with the DNA and RNA synthesis of rapidly dividing cancer cells, leading to their death. It is an antimetabolite chemotherapy drug that mimics the structure of normal DNA and RNA building blocks. Still, its incorporation into DNA and RNA leads to errors in formation and causes damage to the DNA and RNA strands.
Uses of Fluorouracil
Fluorouracil is a chemotherapy medication commonly used to treat different types of cancer, including breast, colon, rectal, stomach, and pancreatic cancers. It works by interfering with the growth and division of cancer cells, ultimately causing them to die.
Fluorouracil Dosage available Fluorouracil is a medication typically administered under a healthcare provider’s supervision, usually in a hospital or clinic setting. The method of administration can vary depending on the type of cancer and the individual patient’s condition. The injection can be given in a vein (intravenous) or muscle (intramuscular) injection. If a patient misses a scheduled dose, they should contact their healthcare provider immediately to determine the next steps. Sometimes, the missed dose may be rescheduled, or a new treatment plan may be recommended. It is important to follow the healthcare provider’s instructions closely and not make any changes to the treatment plan without first consulting with them. Patients should never take a double dose to make up for a missed dose, as this can increase the risk of side effects and toxicity.
Abacavir
Description
This page contains brief details about the drug abacavir, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The FDA approved Abacavir for medical use on 12/17/1998 for the treatment of HIV-1 infection.
Mechanism of Action of Abacavir
Abacavir works by inhibiting the reverse transcriptase enzyme, which is necessary for the replication of HIV. By blocking this enzyme, the drugs help reduce the viral load in the body, slow the progression of HIV infection, and improve the immune system’s function.
Uses of Abacavir
Abacavir is typically used in combination with other HIV medications to manage HIV infection effectively. It works by reducing the HIV levels in the body, thereby enhancing the functioning of the immune system. This reduction in HIV levels helps to lower the risk of HIV-related complications, such as new infections and cancer, ultimately improving the overall quality of life for those affected.
Abacavir Dosage available Abacavir is available as a 300mg tablet in different brands administered under physician direction. Your doctor will decide the most suitable dosage for your case according to your age and physical circumstances.