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  • Rifaximin

    Description

    This page contains brief details about the drug rifaximin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Rifaximin is an antibiotic and received its initial approval from the U.S. Food and Drug Administration (FDA) on May 27, 2004.

    Mechanism of Action of Rifaximin

    Rifaximin acts by binding to the bacterial DNA-dependent RNA polymerase blocking one of the steps in the transcription process. This results in the inhibition of bacterial protein synthesis and consequently inhibits the growth of bacteria.

    Uses of Rifaximin

    It is used to treat traveler’s diarrhea caused by noninvasive strains of Escherichia coli in adults. It is also used to prevent the recurrence of episodes of overt hepatic encephalopathy (symptomatic loss of brain function) in adults with liver disease. This medicine can be used alone or in combination with medicines containing lactulose.

    Rifaximin Dosage available

    Rifaximin is available as a tablet in doses of 200mg, 400mg, and 550mg. Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and duration of the treatment. Take the tablet at the same time every day, with or without food. Swallow the tablets with a glass of water. Do not break, crush, or chew the tablets.

  • Emtricitabine+Tenofovir Disoproxil Fumarate

    Description

    This page contains brief details about the drug emtricitabine,tenofovir disoproxil fumarate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Emtricitabine, Tenofovir disoproxil fumarate contain two active substances, Emtricitabine and Tenofovir disoproxil fumarate. These medications are a part of the standard combination therapy for HIV, known as antiretroviral therapy (ART). It is a combination drug regimen that is commonly used for the effective treatment of HIV-1 infection. When used correctly and consistently, Emtricitabine and Tenofovir disoproxil fumarate have demonstrated high efficacy in HIV treatment and prevention. It is a combination medication for treating and preventing HIV infection that received FDA approval on July 12, 2012.

    Mechanism of Action of Emtricitabine+Tenofovir Disoproxil Fumarate

    Emtricitabine and Tenofovir disoproxil fumarate work by inhibiting HIV replication, reducing viral load, improving immune function, and slowing the progression of HIV disease. In individuals with HIV, these medications help control the virus, maintain a low viral load, and improve overall health outcomes.

    Uses of Emtricitabine+Tenofovir Disoproxil Fumarate

    Emtricitabine and Tenofovir disoproxil fumarate is used to treat HIV -1 Infection.

    Emtricitabine+Tenofovir Disoproxil Fumarate Dosage available To properly consume Emtricitabine and Tenofovir disoproxil fumarate, follow your healthcare provider’s instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider.

  • Eltrombopag

    Description

    This page contains brief details about the drug eltrombopag, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Eltrombopag was first approved by the U.S. FDA on November 20, 2008, for treatment of  thrombocytopenia, chronic hepatitis C, and patients with severe aplastic anemia.

    Mechanism of Action of Eltrombopag

    Eltrombopag works by stimulating megakaryocytes (the large bone marrow cells) that are responsible for producing platelets. By raising the number of platelets in the blood, Eltrompag prevents bleeding and bruising.

    Uses of Eltrombopag

    Eltrombopag has been developed to treat immune (primary thrombocytopenia (ITP) or hepatitis C virus (HCV) infection and also treats low blood counts caused by severe aplastic anemia.

    Eltrombopag Dosage available

    Eltrombopag is available as a tablet to be taken with an empty stomach (1 hour before or 2 hours after a meal). The usual starting dose of an Eltrombopag tablet is 50 mg once daily. Avoid crushing, opening, or dissolving the tablet; swallow it whole with a glass of water. Take this medication as prescribed by your physician. Avoid dairy foods (such as cheese or butter), milk or milkshakes, antacids, and supplements containing iron, aluminum, magnesium, calcium, selenium, zinc, or calcium for 2 hours after or 4 hours before taking this medication.

  • Mycophenolate Sodium

    Description

    This page contains brief details about the drug mycophenolate sodium, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Mycophenolate sodium is an immunosuppressant drug developed by the U.S. Food And Drug Administration for preventing organ rejection in individuals who have previously received an organ transplant.

    Mechanism of Action of Mycophenolate Sodium

    Mycophenolate sodium works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ.

    Uses of Mycophenolate Sodium

    Mycophenolate sodium helps to treat organ rejection in individuals who have previously received an organ transplant (such as kidney, heart, or liver transplantation). It is prescribed as part of a combination therapy that includes other immunosuppressive drugs.

    Mycophenolate Sodium Dosage available

    It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Mycophenolate sodium as prescribed by your doctor. Do not open, crush, break, or chew the medicine.

  • Prucalopride

    Description

    This page contains brief details about the drug prucalopride, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Prucalopride is a stimulant purgative drug developed by the U.S. Food And Drug Administration and initially approved in 2018 for treating chronic idiopathic constipation (CIC).

    Mechanism of Action of Prucalopride

    Prucalopride works by targeting specific serotonin receptors in the digestive system, which helps to stimulate bowel movements and improve the motility of the intestines. By enhancing intestinal contractions, this drug facilitates the movement of stool through the digestive tract, thereby relieving constipation.

    Uses of Prucalopride

    Prucalopride is used to treat chronic idiopathic constipation (CIC) in adults. Chronic idiopathic constipation is a medical condition caused by infrequent bowel movements and difficulty passing stool, which persists over an extended period without an identifiable underlying cause.

    Prucalopride Dosage available

    Take the Prucalopride as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

  • Alprostadil

    Description

    This page contains brief details about the drug alprostadil, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    The U.S. FDA approved Sotalol in 1996 and used to treat erectile dysfunction (ED), peripheral arterial disease (PAD), patent ductus arteriosus (PDA) in Infants and also for diagnostic purposes.

    Mechanism of Action of Alprostadil

    Alprostadil binds to specific receptors on smooth muscle cells in blood vessels and various tissues. When it binds to these receptors, it triggers biochemical events that lead to vasodilation. It relaxes the smooth muscles in blood vessel walls, particularly in the penis, when used for erectile dysfunction. It involves promoting the relaxation of smooth muscle cells, improving blood flow to specific body areas, depending on its intended use.

    Uses of Alprostadil

    It may be used to improve blood flow in patients with peripheral arterial disease (PAD), a condition in which blood flow to the extremities (usually the legs) is reduced. In newborns with certain heart conditions, such as PDA, it can open a blood vessel called the ductus arteriosus. It can also be used in diagnostic tests to assess blood flow in specific body areas, such as during penile Doppler ultrasound studies to evaluate erectile function.

    Alprostadil Dosage available

    Alprostadil is available as an injection and can be administered through intracavernosal injection (into the penis) by the healthcare provider on scheduled appointments. Your doctor will decide the most suitable dosage for your case according to your age and physical circumstances.

  • Pomalidomide

    Description

    This page contains brief details about the drug pomalidomide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Pomalidomide is an antiangiogenic agent (a drug that blocks the formation of blood vessels) which was approved for its medical use on 8th February 2013.

    Mechanism of Action of Pomalidomide

    Pomalidomide is an antiangiogenic agent that is a derivative of thalidomide. Pomalidomide works by inhibiting the formation of blood vessels that supplies nutrition to the cancer cells and facilitates the immune system attack against cancer cells. It arrests the cell cycle and induces programmed cell death of cancer cells.

    Uses of Pomalidomide

    Pomalidomide has been developed to treat Multiple myeloma and Kaposi’s sarcoma. It is effective against cancer cells that are resistant against Lenalidomide.

    Pomalidomide Dosage available Pomalidomide is available in the form of tablet and capsule in the doses 1mg, 2mg and 4mg. You shall take Pomalidomide with or without food by swallowing the tablet or capsule with water once a day. If you are on hemodialysis treatment, take Pomalidomide after hemodialysis on dialysis days.

  • Human Rabies Immunoglobulin

    Description

    This page contains brief details about the drug human rabies immunoglobulin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Human Rabies Immunoglobulin Injection (HRIG) contains Human Rabies Immunoglobulin as an active agent. It is indicated to prevent passive, transient rabies infection after exposure to a rabid animal (dogs, mongooses, jackals, foxes). This injection is formulated from blood plasma from screened donors. Rabies infection spreads when a person is bitten, scratched, or licked by an infected animal, especially when the skin is already injured. Though this infection is 100% fatal, it is 100% preventable with timely measures and the correct use of available vaccines, immunoglobulins, or monoclonal antibodies. The first hepatitis B vaccine was approved by the US Food and Drug Administration (FDA) on December 22, 1999, for post-exposure prophylaxis against rabies.

    Mechanism of Action of Human Rabies Immunoglobulin

    The therapeutic effect of Human Rabies Immunoglobulin is to prevent or treat rabies infection. It works by providing immediate, passive immunity to the rabies virus by neutralizing the virus before it can infect the body’s cells and cause disease. It is usually given along with the rabies vaccine, which helps the body develop its own antibodies against the virus.

    Uses of Human Rabies Immunoglobulin

    Hepatitis B Vaccine is used to Prevention of rabies infection post-exposure to a rabid animal.

    Human Rabies Immunoglobulin Dosage available

    Human Rabies Immunoglobulin is administered as an injection, usually by a healthcare professional. The injection is typically given into the muscle or at the site of the bite wound.

  • Alpelisib

    Description

    This page contains brief details about the drug alpelisib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Alpelisib is an anticancer medication which was approved for its medical use on 24th May 2019.

    Mechanism of Action of Alpelisib

    Alpelisib is a targeted drug therapy for cancer that comes under the class of kinase inhibitors. It acts against the mutation of PI3K genes. PI3K genes are abundant in hormone receptor positive and human epidermal growth factor receptor 2 (HER2) breast cancers. Alpelisib works by stopping the cell signalling of PI3K genes and inhibits the growth and spread of cancer cells. It is often administered in combination with other chemotherapy agents like Fulvestrant.

    Uses of Alpelisib

    Alpelisib Tablet has been developed to treat advanced and metastatic breast cancer in men and menopausal women who have stopped responding to other treatments. It is particularly effective against hormone receptor positive and human epidermal growth factor receptor 2 (HER2) breast cancers caused by mutation in the PIK3CA gene.

    Alpelisib Dosage available Alpelisib is available as a film-coated tablets in the doses 150mg, 200mg, 200+50mg. Swallow the tablet whole with a glass of water without crushing or chewing them.

  • Triptorelin

    Description

    This page contains brief details about the drug triptorelin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Triptorelin was approved for its medical use on 15th June 2000 by the US Food and Drug Administration. It is a medication that belongs to a class of drugs known as gonadotropin-releasing hormone (GnRH) analogs. It is primarily used in the field of reproductive medicine for the treatment of various conditions related to hormonal imbalance.

    Mechanism of Action of Triptorelin

    Triptorelin exerts its therapeutic effect by suppressing the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) through its action on the pituitary gland. This suppression leads to a decrease in the production of sex hormones, such as testosterone and estrogen. By reducing the levels of these hormones, this medication is beneficial in treating hormone-dependent conditions such as prostate cancer, breast cancer, and endometriosis.

    Uses of Triptorelin

    Triptorelin is used for the treatment of Prostate cancer in men, Early onset puberty in children 2 years of age and older (precocious puberty) and used to treat Endometriosis in females – a condition in which the tissue that normally lines the uterus—grows outside of it.

    Triptorelin Dosage available

    Triptorelin is available as a vial for injection in the doses 3.75mg, 11.25mg and 22.5mg.  It is administered as an intramuscular injection into either of the buttocks. Triptorelin is typically administered via injection, either subcutaneously (under the skin) or intramuscularly (into the muscle). The specific dosing and frequency of administration will depend on the individual’s condition being treated and their response to the medication. It is important to follow the healthcare professional’s instructions regarding the administration technique and schedule.