Your cart is currently empty!
Blog
Palonosetron
Description
This page contains brief details about the drug palonosetron, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Palonosetron is an antiemetic drug that belongs to the category of medicines known as alkylating agents. It was approved by the FDA in July 2003 to treat Chemotherapy induced nausea and vomiting.
Mechanism of Action of Palonosetron
Palonosetron is an Isoquinoline derivative that interacts with 5-HT3 receptor antagonists. It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting.
Uses of Palonosetron
Palonosetron is an anti-emetic agent used to treat Postoperative nausea & vomiting. It is also used in the treatment of Chemotherapy induced nausea & vomiting.
Palonosetron Dosage available
Palonosetron is a prescription drug available only in tablet and injection form. The medicine will be administered to you by a qualified healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Palonosetron Hydrochloride Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. If you are taking palonosetron as an oral tablet, it should be swallowed whole with a glass of water, with or without food, as directed by your healthcare provider. Do not crush, chew, or break the tablet before swallowing it.
Factor Vii
Description
This page contains brief details about the drug factor vii, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Factor VII was initially approved by the United States Food and Drug Administration (FDA) on March 25, 1999.
Mechanism of Action of Factor Vii
Factor VII is a blood clotting protein that plays a pivotal role in coagulation. When tissue damage occurs, it interacts with tissue factor (TF) at the injury site, forming the FVIIa-TF complex. This complex acts as an enzyme, triggering a series of reactions that culminate in thrombin formation and the subsequent creation of a blood clot. This mechanism is essential for stopping bleeding after vascular injury.
Uses of Factor Vii
Factor VII is primarily used to treat bleeding disorders. Its key applications include managing bleeding episodes in hemophilia patients with inhibitors, addressing congenital Factor VII deficiency, controlling bleeding during surgery and trauma, managing acquired Factor VII deficiency associated with certain medical conditions, and occasionally, as part of treatment strategies for intracranial hemorrhage.
Factor Vii Dosage available
Factor VII concentrates are typically administered intravenously (IV) to individuals with bleeding disorders. A healthcare provider should determine the specific dosing and administration details based on the patient’s condition and needs.
Nintedanib
Description
This page contains brief details about the drug nintedanib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA-approved Nintedanib treated people with a lung disease such as idiopathic pulmonary fibrosis (IPF), a chronic fibrosing lung disease with a progressive phenotype, systemic sclerosis, on 15th Sept 2014.
Mechanism of Action of Nintedanib
Nintedanib works by inhibiting receptor multiple tyrosine kinases (RTKs) enzyme that develops and progresses lung fibrosis (scarring). Inhibiting these enzymes reduces the development of fibrous tissue in the lungs.
Uses of Nintedanib
Nintedanib is used to treat idiopathic pulmonary fibrosis (IPF), a chronic fibrosing lung disease with a progressive phenotype, systemic sclerosis. This interferes with the production and migration of fibroblasts responsible for lung scars and affects its signaling. This helps to reduce further scarring and stiffening of the lungs.
Nintedanib Dosage available
Take Nintedanib as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration based on your age, body weight, and disease condition. Do not stop taking Nintedanib unless your doctor advises you to stop.
Pegfilgrastim
Description
This page contains brief details about the drug pegfilgrastim, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Pegfilgrastim is a hematopoietic drug that belongs to granulocyte colony stimulated factor (G-CSF) and was approved by the FDA on January 31, 2002, for the treatment of febrile neutropenia and to increase the survival rate in patients receiving myelosuppressive doses of radiation.
Mechanism of Action of Pegfilgrastim
Pegfilgrastim is a colony-stimulating factor that exerts its action by acting on blood-forming cells by binding to specific cell surface receptors, thereby inducing cell division, multiplication, and cell functional activation.
Uses of Pegfilgrastim
Pegfilgrastim is a prescription medication used to decrease the chance of infection caused by low levels of white blood cells in patients with certain types of cancer (non-myeloid) receiving anti-cancer drugs that suppress bone marrow activity. It is also indicated to increase the survival rate in patients receiving radiation therapy that suppresses bone marrow activity.
Pegfilgrastim Dosage available
Pegfilgrastim is available as a pre-filled injection, vial for injection, and on-body injector. The medicine will be administered in the fatty tissues just under your skin (subcutaneously) by a qualified healthcare professional in a hospital setting. The dose and frequency of administration will be decided by your doctor based on your disease condition and other factors.
If your physician decides that Pegfilgrastim can be administered at home by you or your caregiver, then read the “Instructions for use” carefully from the package insert that comes with the medicine. Your doctor or other healthcare professionals will train you on self-administration. Do not administer the medicine if you have not been trained and are not sure about the administration procedure.
Vinorelbine
Description
This page contains brief details about the drug vinorelbine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Vinorelbine is a chemotherapy medication that was approved to be used in 1994.
Mechanism of Action of Vinorelbine
Vinorelbine works by inhibiting the microtubule structures within the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth and multiplication of cancer cells.
Uses of Vinorelbine
Non-small cell lung cancer (NSCLC)
Breast cancer
Vinorelbine Dosage available
Vinorelbine is available as solution for infusion in two doses of 10mg and 50mg.
Midostaurin
Description
This page contains brief details about the drug midostaurin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Midostaurin is an anticancer medication which was approved for its medical use on April 2017.
Mechanism of Action of Midostaurin
Midostaurin is an anticancer medication belonging to the category of medications called kinase inhibitors. It acts against the receptors and proteins that facilitate the mutation of FLT3 gene, interrupts cancer cell signaling, and eventually stops the growth and spread of cancer cells.
Uses of Midostaurin
Midostaurin is a prescription medicine developed to treat acute myeloid leukemia caused by a mutation in FLT3 genes. It is also indicated to treat aggressive system mast cytosis, systemic mast cytosis with hematological neoplasm, and mast cell leukemia.
Midostaurin Dosage available
Midostaurin is available in form of Capsules in the dose 25mg. The usual recommended dosing is 50mg twice daily with food for acute myeloid leukemia and 100mg twice daily for aggressive systemic mast cytosis and systemic mast cytosis. Swallow Midostaurin Capsule whole with a glass of water.
Desmopressin
Description
This page contains brief details about the drug desmopressin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Desmopressin was first approved by the U.S. Food and Drug Administration (FDA) for medical use on November 1, 1978.
Mechanism of Action of Desmopressin
Desmopressin is a medication that mimics the action of the hormone vasopressin in the body. Its therapeutic effect primarily focuses on regulating water balance and reducing excessive urine production. By increasing water reabsorption in the kidneys, it helps alleviate symptoms of conditions such as central diabetes insipidus and bedwetting (nocturnal enuresis). It can also aid in treating mild to moderate von Willebrand disease by promoting the release of von Willebrand factor, a clotting protein.
Uses of Desmopressin
Desmopressin treats conditions such as diabetes insipidus, bedwetting (nocturnal enuresis), and von Willebrand disease.
Desmopressin Dosage available Desmopressin can be administered orally in tablet form, as a nasal spray, or through injection. The specific usage instructions may vary depending on the condition being treated and the form of the medication. Oral tablets are typically taken with water, as directed by the healthcare provider. The nasal spray is administered by spraying into the nostrils, alternating nostrils with each dose. A healthcare professional usually gives injections under the skin or into a vein.
Mesalamine
Description
This page contains brief details about the drug mesalamine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Mesalamine on January 16, 2007. Mesalamine is an anti-inflammatory drug that belongs to the family known as amino salicylates.
Mechanism of Action of Mesalamine
Mesalamine works by reducing gut inflammation. It inhibits inflammatory compounds, counters free radicals, and adjusts the immune response, providing relief, promoting healing, and managing these conditions.
Uses of Mesalamine
Mesalamine is used to treat ulcerative colitis and Crohn’s ileocolitis. Ulcerative colitis and Crohn’s ileocolitis are inflammatory bowel diseases (IBD). Ulcerative colitis mainly inflames the colon and rectum, causing diarrhea and rectal bleeding. Crohn’s ileocolitis affects the small intestine and colon, involving deeper layers of the intestinal wall and leading to abdominal pain, weight loss, and complications.
Mesalamine Dosage available Take the Mesalamine as your physician advises. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Methotrexate
Description
This page contains brief details about the drug methotrexate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Methotrexate is an anti-metabolite and immunosuppressant drug. The FDA approved this for its medical use on 26th February 1999.
Mechanism of Action of Methotrexate
Methotrexate inhibits dihydrofolic acid reductase. Therefore, methotrexate interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow and spread. In treating rheumatoid arthritis, methotrexate is thought to stop or reduce inflammation in the joints by altering the body’s defense mechanism in the immune system.
Uses of Methotrexate
It treats certain types of cancer, such as acute lymphocytic leukemia (ALL), meningeal leukemia, non-hodgkin’s lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer in adults. It is also used to treat severe psoriasis in adults (a skin disease in which red, scaly patches form on some body areas). It is also indicated to treat rheumatoid arthritis in adults.
Methotrexate Dosage available
Methotrexate is available as an injection and tablet. Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this injection. Methotrexate is injected into a vein (intravenously) or into muscle (intramuscularly). Do not self-administer this medicine. If you are prescribed with tablets, do not chew, crush or dissolve the tablets. The score line is only there to help you break the tablet if you have difficulty swallowing it whole. Swallow the tablets whole with water.