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Ertapenem
Description
This page contains brief details about the drug midodrine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Midodrine is an antihypotensive drug approved for its medical use in 2001
Mechanism of Action of Ertapenem
The active metabolite of Midodrine is an alpha1-agonist that works by activating the alpha-adrenergic receptors to exert its effects. It constricts blood vessels and increases blood pressure.
Uses of Ertapenem
It helps to treat orthostatic hypotension ( low blood pressure after sitting or lying down).
Ertapenem Dosage available
The recommended starting dose of Midodrine tablet is 2.5 mg thrice daily with or without food. This dose can be increased weekly to 10 mg three times daily, which is the standard maintenance dose of 30 mg daily. Do not take this medication after the evening or less than three to four hours before bedtime.
Durvalumab
Description
This page contains brief details about the drug durvalumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Durvalumab is an anticancer drug that belongs to the category of medicines known as Anti-PD-1 monoclonal antibodies. It was approved by the FDA in May 2017 to treat certain types of cancer.
Mechanism of Action of Durvalumab
It works by blocking a protein called programmed death-ligand 1 (PD-L1), which is found on the surface of certain cancer cells. When PD-L1 binds to its receptor on T cells, it can inhibit the immune system’s ability to recognize and attack cancer cells. By blocking the interaction between PD-L1 and its receptor, durvalumab allows T cells to recognize and attack cancer cells more effectively. Durvalumab helps the immune system to fight the cancer and potentially slow or stop its growth.
Uses of Durvalumab
Durvalumab is used to treat non-small cell lung cancer(has not spread outside your chest ), small cell lung cancer(has spread within your lungs), and biliary tract cancers(cancer of the bile ducts).
Durvalumab Dosage available
Durvalumab is a prescription drug available in injection form. This injection will be given intravenously into a vein in your arm or hand by a healthcare professional in a hospital setting. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. During the infusion, you will be monitored for any side effects or reactions to the medication. The infusion usually takes a few hours to complete, and you may need to receive multiple infusions over the course of several weeks.
Rituximab
Description
This page contains brief details about the drug rituximab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Rituximab is an immunomodulatory monoclonal antibody (a protein that attaches to a specific target) that was approved for its medical use on 26th November 1997.
Mechanism of Action of Rituximab
Rituximab Injection is a biological agent that belongs to the category of medications called monoclonal antibodies. It specifically targets and binds to the CD20 receptors, resulting in a significant decrease in the inflammatory mediators. The medicine inhibits the availability of B cells by depleting them and eventually stops the growth and multiplication of cancer cells.
Uses of Rituximab
Rituximab Injection has been developed to treat non-Hodgkin’s lymphoma, mature B-cell acute leukemia, chronic lymphocytic leukemia, granulomatosis, rheumatoid arthritis, and pemphigus vulgaris in patients who have not responded adequately to other treatments.
Rituximab Dosage available
Rituximab is available as a single-use vial of injection intended for administration as an intravenous infusion. It is available in doses of 100mg and 500mg. The usual recommended starting dose is 375mg/m2. Your doctor will decide the dose, dosage, and duration of the treatment based on your medical condition.
Polymyxin B
Description
This page contains brief details about the drug polymyxin b, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Polymyxin B is an antibiotic used in gram-negative infection treatment.
Mechanism of Action of Polymyxin B
Polymyxin B acts by disrupting the outer membrane of Gram-negative bacteria. It binds to and interacts with the lipopolysaccharide layer, a crucial bacterial cell wall component, causing membrane destabilization. This leads to increased permeability, leakage of cell contents, and eventual cell death. By targeting the outer membrane, this medication effectively neutralizes Gram-negative bacteria, making it particularly valuable in treating infections caused by these bacteria, especially in cases of multidrug resistance where other antibiotics may not be effective.
Uses of Polymyxin B
Polymyxin B treats severe bacterial infections, especially those caused by Gram-negative bacteria and multi-drug resistant strains. It is commonly used for infections like urinary tract infections, pneumonia, and ventilator-associated pneumonia caused by multidrug-resistant bacteria. This medication is available in intravenous and topical formulations, making it effective for systemic and localized bacterial infections.
Polymyxin B Dosage available
Polymyxin B should be taken exactly as prescribed by a healthcare professional. It is available in various forms, such as tablets or capsules. The dosage and frequency depend on the medical condition being treated. This medication can be taken with or without food, and patients should not adjust the dosage or stop taking it without medical guidance. Following the doctor’s instructions is very important, and if you experience any possible side effects, inform your healthcare provider immediately.
Fondaparinux Sodium
Description
This page contains brief details about the drug fondaparinux sodium, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Fondaparinux sodium was initially approved by the United States Food and Drug Administration (FDA) for medical use on November 29, 2001.
Mechanism of Action of Fondaparinux Sodium
Fondaparinux sodium is an anticoagulant medication that inhibits a specific factor in the blood clotting cascade. Its mechanism of action involves blocking the activity of factor Xa, a crucial enzyme in the coagulation (blood clotting) pathway.
Uses of Fondaparinux Sodium
Fondaparinux sodium is a medication with several important uses in preventing and treating blood clotting disorders. It is primarily employed to reduce the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE), particularly in situations where clot formation is more likely, such as after orthopedic surgeries like hip or knee replacements. It is also utilized to manage acute coronary syndromes (ACS). In addition to its role in preventing these serious conditions, it can be part of the treatment regimen for established cases of DVT and PE, helping to reduce the size of existing blood clots and prevent the formation of new ones.
Fondaparinux Sodium Dosage available
Fondaparinux sodium is typically administered via subcutaneous injection. It is important to follow the dosing instructions as your healthcare provider recommends.
Fludarabine
Description
This page contains brief details about the drug fludarabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Fludarabine is a chemotherapy medication that was approved to be used in 1991.
Mechanism of Action of Fludarabine
Fludarabine works by inhibiting the DNA synthesis in cancer cells, thereby decreasing or stopping them from growing.
Uses of Fludarabine
Fludarabine is a chemotherapy medication that is used in treatment of B-Cell chronic lymphocytic Leukemia (blood cancer).
Fludarabine Dosage available
Fludarabine is given into the vein using an injection and is available in two doses of 10mg and 50 mg.
Human Albumin
Description
This page contains brief details about the drug human albumin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Human Albumin Injection is an albumin solution for injection which was approved by the US Food and Drug Administration for its medical use on 4th August 2014.
Mechanism of Action of Human Albumin
The main mechanism of action of Human Albumin Injection is to increase the colloidal osmotic pressure. It reduces fluid accumulation by pulling the fluid from the intravascular space and increases circulatory blood volume.
Uses of Human Albumin
Human Albumin Injection has been developed to treat hypovolemia, hypoalbuminemia, cardiopulmonary bypass surgery and hemolytic disease of the new born.
Human Albumin Dosage available
Human Albumin is available as 5% and 20% solution for injection. Human Albumin Injection is administered as an intravenous infusion. Your physician will calculate the accurate dose based on your health status and body weight.
Rocuronium Bromide
Description
This page contains brief details about the drug rocuronium bromide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Rocuronium bromide in 1994. Rocuronium bromide is known as muscle relaxants. This medicine is used to induce muscle relaxation during surgeries and in intensive care units (ICU), used in procedures like tracheal tube insertion for artificial ventilation and short-term medical procedures requiring muscle relaxation.
Mechanism of Action of Rocuronium Bromide
Rocuronium bromide acts by blocking the signals between your nerves and muscles, competing with acetylcholine in your body. Acetylcholine normally connects with certain nicotinic cholinergic receptors to make muscles contract. But when this drug is around, it takes the place of acetylcholine, preventing muscle contractions. This happens because it stops the release of calcium ions, which are needed for muscle contraction. Thus, keeping your muscles relaxed.
Uses of Rocuronium Bromide
Rocuronium bromide is used to induce muscle relaxation in tracheal tube insertion for artificial ventilation and in intensive care unit surgery (ICU).
Rocuronium Bromide Dosage available
This medicine is given only in a hospital setup by a healthcare provider. Rocuronium bromide will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Fosaprepitant Dimeglumine
Description
This page contains brief details about the drug fosaprepitant dimeglumine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved fosaprepitant dimeglumine on 1/25/2008, It is used to prevent nausea and vomiting caused by chemotherapy (cancer treatment).
Mechanism of Action of Fosaprepitant Dimeglumine
Fosaprepitant dimeglumine injection blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting.
Uses of Fosaprepitant Dimeglumine
Fosaprepitant dimeglumine treats bacterial infections (respiratory tract, urinary tract, nervous system, digestive system, and blood poisoning. It is effective only against bacterial infection and not against viral or fungal infection.
Fosaprepitant Dimeglumine Dosage available
Fosaprepitant dimeglumine is available as an IV (intravenous) injection in the dose of 150 mg. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Somatropin/Recombinant Human Growth Hormone
Description
This page contains brief details about the drug somatropin/recombinant human growth hormone, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Somatropin is a recombinant human growth hormone which was approved for its medical use in 1987.
Mechanism of Action of Somatropin/Recombinant Human Growth Hormone
Somatropin Injection is equivalent to human pituitary hormone that helps in growth. It regulates the amount of insulin-like growth factor-I (IGF-I) and improves linear growth in patients with growth hormone deficiency.
Uses of Somatropin/Recombinant Human Growth Hormone
Somatropin Injection has been developed to treat growth failure in children due to deficiency of growth hormone, Prader Willi syndrome, Turner’s syndrome, small for gestational age and short stature of unknown cause. It is also indicated for adults with growth hormone deficiency of childhood or adult onset.
Somatropin/Recombinant Human Growth Hormone Dosage available
Somatropin Injection is available as prefilled syringe in the doses 4mg, 5mg, 10mg, 15mg, 4IU, 10IU, 16IU and 36IU. This injection is intended for administration through subcutaneous route and the dosing varies according to body weight and disease condition.