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  • Midodrine

    Description

    This page contains brief details about the drug midodrine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Midodrine is an antihypotensive drug approved for its medical use in 1996

    Mechanism of Action of Midodrine

    The active metabolite of Midodrine is an alpha1-agonist that works by activating the alpha-adrenergic receptors to exert its effects. It constricts blood vessels and increases blood pressure.

    Uses of Midodrine

    It helps to treat orthostatic hypotension ( low blood pressure after sitting or lying down).

    Midodrine Dosage available

    The recommended starting dose of Midodrine tablet is 2.5 mg thrice daily with or without food. This dose can be increased weekly to 10 mg three times daily, which is the standard maintenance dose of 30 mg daily. Do not take this medication after the evening or less than three to four hours before bedtime.

  • Human Normal Immunoglobulin

    Description

    This page contains brief details about the drug human normal immunoglobulin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Human Normal Immunoglobulin is an immunomodulatory agent which was approved for its medical use in 1981.

    Mechanism of Action of Human Normal Immunoglobulin

    Human Normal Immunoglobulin Injection belongs to the class of immunostimulants. Human Normal Immunoglobulin works by restoring the immunoglobulin G (IgG) antibodies. It directly binds to the Fc fragment specific receptors, acts against inflammatory mediators and induces cell death in B cells and T cells, eventually reducing inflammation and reducing the severity of infections.

    Uses of Human Normal Immunoglobulin

    Human Normal Immunoglobulin Injection has been developed to treat adults with inflammatory disorders, primary and secondary immunodeficiencies.

    Human Normal Immunoglobulin Dosage available

    Human Normal Immunoglobulin is available as a vial containing solution for injection, intended for administration as an intravenous infusion. It is available in the doses 0.5g, 2.5g, 5g, 10g, and 16.5%. The dosing and frequency vary according to the medical condition and bodyweight.

  • Benralizumab

    Description

    This page contains brief details about the drug benralizumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Benralizumab is an antiasthmatic drug developed by the U.S. Food And Drug Administration and initially approved in Nov 2017 for treating severe eosinophilic asthma.

    Mechanism of Action of Benralizumab

    Benralizumab works by binding to a specific protein called interleukin-5 receptor alpha (IL-5Rα) on the surface of eosinophils, a type of white blood cell that plays a key role in the inflammation and narrowing of the airways in asthma. By binding to IL-5Rα, this drug reduces the number of eosinophils in the blood and airways, helping to decrease airway inflammation and improve asthma symptoms.

    Uses of Benralizumab

    Benralizumab is used to treat severe eosinophilic asthma, a subtype of asthma caused by high levels of eosinophils in the blood and airways. It is also approved for treating eosinophilic granulomatosis with polyangiitis (EGPA), a rare autoimmune disease affecting blood vessels and organs.

    Benralizumab Dosage available

    Benralizumab will be given by injection under the skin (subcutaneous). Your doctor, nurse, or other healthcare professional will show you how to inject the medicine. Do not try to administer the medicine if you are well-trained. Your physician will decide the injection dose based on your disease condition and severity.

  • Epirubicin

    Description

    This page contains brief details about the drug epirubicin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Epirubicin is an antineoplastic drug that belongs to the class anthracyclines. FDA approved epirubicin on November 15, 2006, for the treatment of breast cancer, stomach, and bowel cancer, ovarian cancer, and lung cancer.

    Mechanism of Action of Epirubicin

    Epirubicin inhibits DNA, RNA, and protein synthesis by exerting cytotoxic activity. It works by slowing or stopping the growth of the cancer cells. This medicine helps to selectively kill the cancer cells rather than the normal, healthy cells.

    Uses of Epirubicin

    Epirubicin is an intravenously administered drug. This medicine is used as adjuvant therapy in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is also useful in treating breast, ovaries, stomach, bowel, and lung cancers. In addition, this medicine is also used to treat cancers of the blood-forming tissues, such as malignant lymphomas, leukemias, and multiple myeloma.

    Epirubicin Dosage available The drug should be administered only by healthcare professionals experienced with cancer chemotherapy. Your physician will determine the dose and frequency of administration based on the type of cancer and severity of the disease.  The medicine will be given as an infusion into a vein. Do not self-administer the injection.

  • Trastuzumab Deruxtecan

    Description

    This page contains brief details about the drug trastuzumab deruxtecan, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Trastuzumab deruxetecan was first approved by the United States Food and Drug Administration (FDA) on December 20, 2019.

    In a 2021 study, researchers assessed the safety and activity of trastuzumab deruxtecan (T-DXd) in patients with various HER2-expressing or HER2-mutant solid tumours. They reported a confirmed objective response rate (ORR) of 28.3% and a median progression-free survival (PFS) of 7.2 months.

    The study highlighted promising activity in HER2-mutant non-small cell lung cancer (NSCLC) and other solid tumours.

    Mechanism of Action of Trastuzumab Deruxtecan

    Trastuzumab deruxetecan is an antibody-drug conjugate that targets HER2. It uses a humanised anti-HER2 IgG1 antibody. Trastuzumab deruxetecan includes a small molecule called DXd, which inhibits topoisomerase I and is linked to the antibody by a cleavable connector.

    Once it binds to HER2 on cancer cells, Trastuzumab deruxetecan is taken into the cell. Inside the cell, the linker is broken down by lysosomal enzymes, releasing DXd. This molecule then causes DNA damage and triggers cell death.

    Uses of Trastuzumab Deruxtecan

    Trastuzumab deruxetecan is used in the treatment of the following:

    HER2-positive metastatic breast cancer: Treat adult patients with inoperable or metastatic HER2-positive breast cancer who have already received a prior anti-HER2-based treatment.

    HER2-low metastatic breast cancer: Treat adult patients with inoperable or metastatic HER2-low breast cancer who have undergone prior chemotherapy in the metastatic setting or experienced cancer recurrence during or within six months of completing adjuvant chemotherapy.

    Locally advanced or metastatic gastric cancer: Treat adult patients with locally advanced or metastatic HER2-positive gastric or gastroesophageal junction adenocarcinoma who have already received a prior trastuzumab-based treatment.

    Trastuzumab Deruxtecan Dosage available

    Trastuzumab deruxtecan is available as an injection and administered intravenously (into a vein) by the healthcare provider on scheduled appointments. Your healthcare provider will decide the suitable dosage for your condition according to your age and physical circumstances.

  • Treosulfan

    Description

    This page contains brief details about the drug treosulfan, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Treosulfan was approved by the FDA for medical use on 04/08/2015 as part of a conditioning treatment for patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT).

    Mechanism of Action of Treosulfan

    Treosulfan is an alkylating agent. Its mechanism is to cause damage to the DNA structure, leading to inhibition of DNA replication and cancer cell death.

    Uses of Treosulfan

    Treosulfant is an anti-neoplastic medication belonging to the group called alkylating agents. This medicine is combined with Fludarabine to treat allogeneic hemopoietic stem cell transplant (alloHSCT) in adults with both malignant and non-malignant. In pediatric patients (older than one month), it treats malignant.

    Treosulfan Dosage available

    Treosulfan injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

  • Minocycline

    Description

    This page contains brief details about the drug minocycline, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Minocycline is an antibiotic drug developed by the U.S. Food And Drug Administration and initially approved for treating respiratory tract infections, urinary tract infections, skin infections, meningitis, syphilis, chlamydial infection, and acute ischemic stroke.

    Mechanism of Action of Minocycline

    Minocycline works by inhibiting the growth and reproduction of bacteria. It does this by interfering with the protein synthesis process within bacterial cells, ultimately preventing the bacteria from multiplying and causing infection.

    Uses of Minocycline

    Minocycline is used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, skin infections, meningitis, syphilis, chlamydial infection, and acute ischemic stroke. This medication is also valuable in cases where patients cannot receive penicillin antibiotics due to allergies or other reasons.

    Minocycline Dosage available

    Minocycline can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

  • Darunavir

    Description

    This page contains brief details about the drug darunavir, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    The U.S. FDA-approved Darunavir to treat people with HIV infection on June 23, 2006.

    Mechanism of Action of Darunavir

    Darunavir tablet inhibits the activity of the HIV protease enzyme, which is responsible for the replication of the virus. This prevents the production of mature and infectious viral particles.

    Uses of Darunavir

    Darunavir has been developed to treat Human Immunodeficiency Virus (HIV-1). Darunavir tablet is indicated as a complete regimen for treating adults and children older than three years of age infected with HIV 1.

    Darunavir Dosage available

    Take the Darunavir tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

  • Darunavir + Ritonavir

    Description

    This page contains brief details about the drug darunavir,ritonavir, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    Darunavir, Ritonavir is a combination regimen consisting of antiviral medications, which was approved for its medical use on 23rd June 2006.

    Mechanism of Action of Darunavir + Ritonavir

    Darunavir, Ritonavir Tablet is an antiviral combination of medicine that belongs to the category of protease inhibitors. The protease enzyme forms the final protein structure of the HIV. Darunavir and Ritonavir works by inhibiting the action of protease enzymes and leads to the formation of HIV proteins with poor morphology. This, in turn, stops the replication of the virus.

    Uses of Darunavir + Ritonavir

    Darunavir, Ritonavir has been developed to treat Human Immunodeficiency Virus (HIV-1). Darunavir, Ritonavir Tablet is indicated as a complete regimen for treating adults and children older than 3 years of age, infected with HIV 1.

    Darunavir + Ritonavir Dosage available

    Darunavir, Ritonavir is available as film coated tablets consisting of 600mg of Darunavir and 100mg of Ritonavir. The usual recommended dosage of this combination regimen is one tablet everyday with or without food.

  • Trypsin,Bromelain,Rutoside Trihydrate

    Description

    This page contains brief details about the drug trypsin,bromelain,rutoside trihydrate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

    Date of Approval

    The trypsin + bromelain + rutoside trihydrate is medically approved to relieve pain in rheumatoid arthritis, osteoarthritis, management of edema and inflammation and stimulate muscle contraction.

    Mechanism of Action of Trypsin,Bromelain,Rutoside Trihydrate

    Trypsin is an enzyme that helps the body build healthy tissues by removing dead skin cells. Bromelain is a pineapple extract that acts by decreasing plaque or clots at the injured site to reduce fibrin production. Trypsin and Bromelain work together to reduce edoema and inflammation by creating chemicals in the body that fight pain and swelling. Rutoside is an antioxidant that works by preventing cell damage, eliminating toxins, and protecting the body from free radicals and toxins.

    Uses of Trypsin,Bromelain,Rutoside Trihydrate

    The trypsin + bromelain + rutoside trihydrate is medically approved to relieve pain in rheumatoid arthritis, osteoarthritis, management of edema and inflammation and stimulate muscle contraction.

    Trypsin,Bromelain,Rutoside Trihydrate Dosage available

    The trypsin + bromelain + rutoside trihydrate can be administered orally. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.