Adpem (Pemetrexed) Injection

Generic brands for Pemetrexed Injection  Available in India Brand Name Adpem Generic Name Pemetrexed Strength 500mg Manufacturer Adley Formulations

Description

Description

This page contains brief details about the drug pemetrexed, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The U.S. FDA-approved Pemetrexed is an anticancer medication to treat malignant pleural mesothelioma and non-small cell lung carcinoma, on 04th February 2004.

Mechanism of Action of Pemetrexed

Pemetrexed inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.

Uses of Pemetrexed

Pemetrexed is used to treat non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). Pemetrexed Injection is given alone or in combination with another anticancer medicine, such as Cisplatin.

Pemetrexed Dosage available

Pemetrexed is an intravenous infusion drug that is injected through the veins. Your physician will choose the dosage and administration frequency based on your medical condition because it differs for each person.

 

News/Updates

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs,7th edition, 2013, 863.
  2. Eagle Pharmaceuticals, US Food and Drug Administration, [ Revised on Feb 2020] [ Accessed on 27 – March – 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/209472s000lbl.pdf
  3. Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc), [ Accessed on 27 – March – 2023], https://www.medicines.org.uk/emc/files/pil.8887.pdf