Adrim (Doxorubicin) Injection

Generic brands for Doxorubicin Injection  Available in India Brand Name Adrim Generic Name Doxorubicin Strength 10mg, 50mg Manufacturer Fresenius Kabi India Pvt

Description

Description

This page contains brief details about the drug doxorubicin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The  U.S. FDA-approved Doxorubicin is an anticancer medication to treat main types of cancers, on 07th September 1993.

Mechanism of Action of Doxorubicin

Doxorubicin works by interfering with the DNA in cancer cells by inserting itself into the DNA strands, which disrupts the normal structure of the DNA. This causes the DNA to break apart, leading to cell death. Additionally, doxorubicin can also cause damage to the membranes surrounding the cell’s nucleus, which further contributes to cell death.

Uses of Doxorubicin

Doxorubicin is used to treat various types of cancer, especially breast cancer, lung cancer, Malignant lymphomas, and certain types of leukemia. It is either used alone or in combination with other drugs.

Doxorubicin Dosage available

Doxorubicin is an intravenous infusion drug that is injected through the veins. Your physician will choose the dosage and administration frequency based on your medical condition because it differs for each person.

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References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1714.
  2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867.
  3. Pfizer Limited, Electronic medicines compendium (emc), [Revised on Feb 2021], [ Accessed on 25 Mar 2023], https://www.medicines.org.uk/emc/files/pil.6184.pdf
  4. Bedford Laboratories, US Food and Drug Administration, [Revised on April 2013], [ Accessed on 25 Mar 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/050467s073lbl.pdf