Adstem (Plerixafor) Injection

Description

Description

This page contains brief details about the drug plerixafor, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The U.S. FDA-approved Plerixafor is used to collect blood stem cells. Additionally, it is also used in lymphoma (WBC cancer), multiple myeloma (plasma cell cancer in bone marrow), or solid tumor On 15th December 2008.

Mechanism of Action of Plerixafor

Plerixafor injection works by blocking a protein called CXCR4 (chemokine receptor) on stem cells, which helps them move from the bone marrow into the bloodstream. By blocking CXCR4, Plerixafor causes the stem cells to be released into the bloodstream where the stem cells can be collected and isolated using a machine and stored for transplantation.

Uses of Plerixafor

Plerixafor is used to collect blood stem cells for collection, storage, and transplantation., lymphoma and multiple myeloma in adults, lymphoma or solid tumors in children (aged between 1 to 18).

Plerixafor Dosage available

Plerixafor injection is administered as a subcutaneous injection (under your skin). If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.