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Apaluside (Apalutamide) Tablet
Generic brands for Apalutamide Injection Available in India Brand Name Apaluside Generic Name Apalutamide Strength 60mg Manufacturer Lucien Life Sciences
Description
Description
This page contains brief details about the drug apalutamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Apalutamide is an anticancer drug in the androgen receptor inhibitors class of medications. The FDA approved the medicine for its medical use on September 17, 2019.
Mechanism of Action of Apalutamide
Apalutamide is a selective androgen receptor (AR) inhibitor that binds directly to the androgen receptor binding domain. It inhibits protein transportation in the nucleus, DNA binding, and AR-mediated transcription. Treatment with Apalutamide reduces cancer cell growth and increases cell death, resulting in effective anticancer activity.
Uses of Apalutamide
It is indicated for treating patients with certain types of prostate cancer whose cancer has spread to other parts of the body and still responds to a medical or surgical treatment that lowers testosterone (male reproductive hormone) or whose cancer has not spread to other parts of the body and no longer responds to a medical or surgical treatment that lowers testosterone.
Apalutamide Dosage available
Apalutamide is an orally administered drug. Take medicine as informed by your physician. It is generally taken with or without food once a day. Take the tablet at around the same time every day. Swallow the tablets whole; do not split, chew, or crush them. Do not stop taking Apalutamide without talking to your doctor.
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References
- Highlights Of Prescribing Information – Apalutamide. (2019).Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210951s001lbl.pdf [Accessed January 13, 2023].
- 2021 (2021). Apalutamide: MedlinePlus Drug Information. [online] medlineplus.gov. Available at: https://medlineplus.gov/druginfo/meds/a618018.html [Accessed January 13, 2023].
- PATIENT INFORMATION ERLEADA ® (er lee’dah) (apalutamide). (2022). [online] Available at: https://www.janssenlabels.com/package-insert/product-patient-information/ERLEADA-ppi.pdf [Accessed January 13, 2023].
- www.cancer.gov. (2018). Apalutamide – National Cancer Institute. [online] Available at: https://www.cancer.gov/about-cancer/treatment/drugs/apalutamide [Accessed January 13, 2023].