Aprelieva (Aprepitant) Capsule

Generic brands for Aprepitant Injection  Available in India Brand Name Aprelieva Generic Name Aprepitant Strength 125mg/80mg Manufacturer Allieva Pharma Pvt. Ltd.

Description

Description

This page contains brief details about the drug aprepitant, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The U.S. FDA-approved Aprepitant to prevent nausea and vomiting due to chemotherapy on 26th March 2003.

Mechanism of Action of Aprepitant

Aprepitant capsule blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.

Uses of Aprepitant

Aprepitant is used to prevent nausea and vomiting due to chemotherapy in adults and children of twelve years and older.

Aprepitant Dosage available

Swallow the Aprepitant capsule as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the dosage based on your medical condition because it differs for each person. Only stop taking Aprepitant if your doctor advises you to stop.

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References

  1. KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
  2. Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1345.
  3. Ethypharm, Electronic Medicines Compendium (EMC), [Revised on Oct 2022]; [Accessed on 19th April 2023], https://www.medicines.org.uk/emc/files/pil.14650.pdf
  4. Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date April 2015], [Accessed on 19th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021549s025lbl.pdf