Axilieva (Axitinib) Tablet

Generic brands for Axitinib Injection  Available in India Brand Name Axilieva Generic Name Axitinib Strength 1mg, 5mg Manufacturer Allieva Pharma Pvt. Ltd.

Description

Description

This page contains brief details about the drug axitinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Axitinib is an antineoplastic agent which was approved for its medical use on 27th January 2012.

Mechanism of Action of Axitinib

Axitinib is a biological agent that acts as targeted drug therapy in cancer treatment. It is an anticancer medication that belongs to the category of tyrosine kinase inhibitors. It interferes with the growth of blood vessels inside the cancer cells and also acts against proteins called receptor tyrosine kinases to interrupt cell signaling, ultimately stopping the growth and spread of cancer cells.

 

Uses of Axitinib

Axitinib has been developed to treat a type of kidney cancer (Renal cell carcinoma) after disease progression and inadequate response to other anticancer therapies.

 

Axitinib Dosage available

Axitinib is available in the form of film-coated tablets in doses of 1mg, 3mg, 5mg, and 7mg. The usual recommended dose is 5mg twice a day. Your healthcare provider will adjust the dosing according to how well your body tolerates this medication.

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News/Updates

References

  1. Pfizer, [Revised on 13th Jan 2020] [Accessed on 23rd March 2023], https://www.pfizer.ca/sites/default/files/202001/INLYTA_PM_Approved_03Jan2020_E_DC.pdf
  2. Pfizer Labs, Electronic Medicines Compendium(EMC), [Revised on Mar 2021] [Accessed on 23rd March 2023], https://www.medicines.org.uk/emc/files/pil.4325.pdf
  3. Pfizer, Fact sheet, [Revised on Sep 2012] [Accessed on 23rd March 2023], https://cdn.pfizer.com/pfizercom/news/esmo/renal_cell_carcinoma_fact_sheet.pdf
  4. Annex I summary of Product Characteristics – European Medicines Agency. Available at:https://www.ema.europa.eu/en/documents/product-information/inlyta-epar-product-information_en.pdf (Accessed on March 25, 2023).
  5. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.